Nozepamum
Application instruction:
Nozepamum – drug with the anxiolytic, calming, somnolent, weak anticonvulsant and myorelaxation action.
Form of release and structure
Dosage form – tablets (on 10 pieces in blister strip packagings, in a pack of cardboard 5 packagings; on 50 pieces in banks from light-protective glass or in polymeric banks, in a pack of cardboard 1 bank).
Active ingredient: Nozepamum (oxazepam), its contents in 1 tablet makes 10 mg.
Excipients: potato starch, sugar milk (lactose), talc, calcium stearate.
Indications to use
- Tension, concern and fears of any nature of an origin;
- Vegetative lability at women;
- Neurosises, frustration of a dream and a hyperexcitability at an alcoholism.
Contraindications
Absolute:
- Acute respiratory insufficiency;
- The expressed myasthenia;
- Acute renal or liver failure;
- Psychoses;
- Heavy depression;
- Shock;
- Coma;
- Closed-angle glaucoma;
- Intoxication alcohol or medicines;
- Children's age up to 6 years;
- Period of pregnancy and lactation;
- Hypersensitivity to drug components.
Route of administration and dosage
Nozepamum should be accepted inside. Meal does not influence efficiency of drug.
Therapy there begin with a dose 10 mg 2-3 times a day. The average effective dose at out-patient treatment makes 30-50 mg a day, at hospitalization, especially in serious and acute conditions, can reach 120 mg a day.
At sleeplessness appoint on 10-30 mg in 45-60 minutes prior to a dream.
At alcoholic abstinence – on 10-30 mg 3-4 times a day.
For elderly people the initial dose makes on 10 mg 3 times a day. Depending on indications it is possible to accept 10 mg of 1 times a day. If there is a need, but on condition of good tolerance, the single dose is increased to 20 mg by 3 times a day. For patients 65 years the highest resolved daily dose – 40 mg are more senior.
Duration of therapy is defined individually depending on a condition of the patient and efficiency of therapy. Average duration makes 14-28 days.
Side effects
- Frequent: general weakness, drowsiness, increased fatigue, headache, concern, weakness of muscles, ataxy, paradoxical reactions, decrease in a libido, disturbance of an urination, hypotonia, skin allergic reactions (itch, rash, urticaria), accustoming, medicamentous dependence;
- Rare: dyspepsia, yellowness, disturbance of work of a liver, dryness in a mouth, a photophobia, an alalia, a tremor, euphoria, a photophobia, bulimia, disturbance of memory, coordination of movements and gait, a leukopenia.
At exceeding of the recommended dose are possible: block of work of the central nervous system (drowsiness, confusion of consciousness, decrease in reflexes, lethargy and even coma), ataxy, hypotonia, hypnotic state.
Special instructions
Nozepamum oppresses work of the central nervous system therefore during therapy it is necessary to refrain from driving of the car and performance of potentially dangerous works requiring special attention and high speed of reactions.
Drug should not be cancelled sharply, it is necessary to reduce a dose gradually.
Medicinal interaction
Nozepamum can influence efficiency of anticoagulants of indirect action.
Drug strengthens effect of alcohol, the cholinolytics and other medicines influencing the central nervous system (sedative, somnolent, antiepileptic, psychotropic).
Terms and storage conditions
To store at a temperature up to 30 ºС in protected from light, the place, unavailable to children.
Period of validity – 5 years.
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