Sangviritrin

Sangviritrin – antimicrobic medicine of a plant origin.

Pharmacological action

Active components of Sangviritrin possess a wide range of antimicrobic action, and also antikholinesterazny activity.

Drug is active in the relation:

• Pathogenic fungi of the sort Trichophyton, Microsporum, Aspergillus, Nocardia;
• Gram-positive and gram-negative bacteria – Cryptococcus spp., Streptococcus spp., Antracoides spp., Staphylococcus spp., Shigella spp., Enterococcus spp., Salmonella spp., Escherichia spp., Acinetobacter spp., Proteus spp., Pseudomonas spp., Citrobacter spp., Klebsiella spp., Serratia spp.;
• Many polyresistant strains of microorganisms;
• Some pathogenic protozoa – Trichomonas vaginalis, Entamoeba histolytica;
• Drozhzhepodobny mushrooms of the sort Candida.

Release form

Mix of bisulphates – a heleritrin hydrosulphate and a sangvinarin hydrosulphate which is received from a grass of a maklea microcarpous also by makle heart-shaped is Sangviritrin's part.

Dosage forms of Sangviritrin:

• The dark orange tablets of a round form covered with a kishechnorastvorimy cover containing 5 mg of active ingredient;
• Orange color spirit solution for external and topical administration (0,2%), in bottles on 10, 25 and 50 ml;
• Linimentum for external use, in banks from orange glass on 10 g (0,5%) and 20 g (0,5% or 1%).

For preparation of aqueous solutions use Sangviritrin's tablets which dissolve before use in hot water.

Sangviritrin's analogs on a way of action are: solution for external use the Dioxidin, Diksin, tincture of Galenofillipt, tablet 5-HOK, Geksametilentetramin, Zivoks, Nitroksolin, Zeniks, Nitroksolin-AKOS.

Indications to Sangviritrin's use

According to the instruction Sangviritrin appoint for treatment:

• Infectious and inflammatory diseases of a uterus and vagina, including a colpitis, an endocervicitis, an erosion of a neck of uterus, the vulvitis infected postoperative wounds. At these indications Sangviritrin it is possible to apply also at pregnant women;
• Diseases of a middle ear, and also outside acoustical pass.

In complex therapy of chronic and acute pyoinflammatory diseases Sangviritrin according to the instruction appoint at:

• Acute intestinal infections, including salmonellosis, dysentery and food toxicoinfections;
• Dysbacterioses;
• Wound fevers;
• Diseases which cause a pathogenic fungi, including candidiasis, a pharyngomycosis, a microsporia;
• Various infectious complications which are caused by pathogenic microflora (a rekonvalestsentny bacteriocarrier).

Also Sangviritrin according to the instruction apply at treatment of cerebral palsy and poliomyelitis (as a part of a combination therapy).

Besides, Sangviritrin is according to reviews effective for prevention of pyoinflammatory wound fevers after operations and diseases of skin at newborns at:

• Pyoderma, dermatomycosis, eczema, onychomycosis, superficial zymonematosis;
• Infectious and inflammatory diseases of skin and mucous membranes, including periodontosis, contaminated wounds, an alveolar pyorrhea, a periodontal disease, aphthous stomatitis, an ulcer and necrotic gingivostomatitis;
• The burns open the infected changes, it is long not healing wounds and trophic ulcers;
• Tonsillitis and otitis.

Contraindications

According to the instruction Sangviritrin it is contraindicated to apply in the following cases:

• At epilepsy;
• At bronchial asthma;
• At stenocardia;
• In the presence of fungal infections of skin against the background of eczematization;
• At hyperkinesias;
• At a liver or renal failure;
• In cases if there is a hypersensitivity to Sangviritrin's components.

Route of administration of Sangviritrin

In a tablet Sangviritrin is recommended to accept after food.

The daily dose for adults varies from 30 to 45 mg of Sangviritrin divided into 3-4 receptions.

To children of 1-3 years Sangviritrin appoint at the rate of 5 mg to every year of life.

To children up to 10 years reception of 5 mg of drug 3-4 times a day, but no more than 20 mg a day is recommended, to children up to 15 years – to 30 mg a day.

Duration of a course of treatment Sangviritrin averages:

• At a bacteriocarrier – one-two weeks;
• At acute intestinal infections, including salmonellosis, dysentery and food toxicoinfections – from 5 to 10 days;
• At a microsporia prolonged treatment – 4-5 weeks;
• At dysbacterioses, a pharyngomycosis and candidiasis – up to two weeks.

At a superficial zymonematosis Sangviritrin apply outwardly, greasing daily the defeat centers with linimentum one - twice a day within a week.

At treatment of ulcers it is also long not healing wounds Sangviritrin in the form of linimentum impose on a wound surface daily or once in two days.

Locally Sangviritrin according to the instruction apply as follows:

• At stomatitises – applications by linimentum for 5 days on affected areas of a mucous membrane of an oral cavity to three times a day;
• At chronic purulent average otitis – 5-8 drops of 0,2% of spirit solution dig in up to three times a day;
• In gynecology 1-2 times a day apply lotions of 0,005-0,01% of warm aqueous solution of Sangviritrin up to 10 days;
• At outside otitis for 10-15 minutes enter the turundas moistened with spirit solution of Sangviritrin (0,2%) to three times a day into acoustical pass;
• At newborns at pyoinflammatory diseases of skin for the first week of life moisten folds of skin of 0,2% with aqueous-alcoholic solution;
• At the open infected changes use aqueous solution (0,01-0,1%);
• At parodontita apply turundochka which moisten in 0,2% aqueous-alcoholic solution of Sangviritrin.

The maximum daily dose of Sangviritrin at topical and external use at adults and children is more senior than 5 years:

• Aqueous solutions – 30 ml;
• Aqueous-alcoholic solutions – to 15 ml.

At children up to 5 years the maximum daily dose of Sangviritrin makes:

• Aqueous solutions – 20 ml;
• Aqueous-alcoholic solutions – no more than 10 ml.

Side effects

Sangviritrin according to reviews can lead to insignificant frustration of the alimentary system which are shown in the form of diarrhea, an abdominal pain, nausea and vomiting. Side effects decrease at Sangviritrin's reception after food, along with sugar or syrup.

At sensitivity to active components allergic reactions can be shown. In a site of application Sangviritrin according to reviews can cause morbidity, an itch, burning and a dermahemia. Morbidity and burning at use of solution decrease at addition of 0,5% of solution of Procainum.

Storage conditions

Sangviritrin treats OTC antimicrobic medicines of a plant origin with a period of storage of 36 months.