Tiaprid
Application instruction:
Tiaprid – the drug with an antipsychotic orientation intended for treatment of diseases of a nervous system.
Pharmacological action
Tiaprid by the nature is an atypical neuroleptic. 
It renders the antipsychotic, anesthetizing, sedative, anxiolytic and somnolent action. The mechanism of its action consists in blocking of receptors of various structures of a brain. It is capable to contact selectively dopamine receptors 2 types in mesolimbic and mesocortical zones, practically without influencing receptors of 1 type thanks to what antipsychotic action is implemented. Influencing the same receptors in a hypothalamus (in the center of thermal control), Tiaprid renders hypothermal effect, in the emetic center - antiemetic effect. Sedative action is caused by blocking of adrenoceptors in a reticular formation of a brain.
Tiaprid well eliminates somatic and visceral pain. It suppresses productive symptomatology, eliminates central dyskinesia, strengthens action of other neuroleptics, lowers a threshold of epileptic activity at patients with epilepsy and improves cognitive abilities at elderly.
Drug gets almost at once to blood at intake, and the concomitant use of food worsens Tiaprid's absorption. It well passes through a blood-brain barrier. Tiaprid is brought from an organism in not changed look by kidneys.
Release form
Tiaprid according to the instruction produce in tablets 100 mg and in solution for intramuscular and intravenous administration in ampoules on 2 ml (50 mg/ml).
Indications to Tiaprid's use
Drug is used for treatment of hyperkinesias and diskineziya, including at parkinsonism. Apply it at a nervous tic, a tremor, in case of an acute and chronic chorea, at behavior disorders at senile age, at psychomotor excitement and alcoholism.
According to reviews Tiaprid well eliminates pains in case of a chronic pain syndrome, at oncological patients, pains of a neurogenic origin, a headache. It is capable to eliminate behavior disorders with aggression and agitation.
Contraindications
Tiaprid it is impossible to use in the presence at patients of prolaktinzavisimy tumors, a pheochromocytoma, at hypersensitivity to drug, during pregnancy and a lactation, at children up to 7 years. With care it is applied in case of epilepsy, dekompensirovanny heart diseases, a chronic renal failure. During treatment by drug it is necessary to refrain from the work demanding concentration of attention.
Application instruction of Tiaprid
Tiaprid accept inside in minimum effective dose, begin treatment with a low dose. For adults it averages 2 – 4 tablets a day.
In case of motive frustration the dose makes 1 – 2 tablets 3 times a day, at psychomotor excitement the most admissible dose of 12 tablets in days.
At headaches, alcoholism begin with 200 – 400 mg/days, gradually reducing a drug dose to 100 – 200 mg/days.
At a chorea Tiaprid according to the instruction accept since 25 mg/days, gradually bringing it to 300 – 800 mg/days.
The children's dosage is calculated on body weight, and since 7 years makes 3 – 6 mg/kg/days.
At intravenous and intramuscular administration in case of severe pains 200 – 400 mg/days, to children from 7 years – 100 – 150 mg/days there are enough. Duration of treatment is individual, it is determined by the doctor depending on dynamics of symptoms.
Side effects of Tiaprid
According to reviews Tiaprid is capable to cause drowsiness, dizzinesses, headaches, disturbances of a menstrual cycle, increase in mammary glands, a galactorrhoea.
Name of drug
Price
Drugstore
Tiaprid тбл 100 mg No. 30, Organic chemistry (Novokuznetsk)
1419 rub.
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