Acetone at pregnancy

During incubation of the child the organism of future mother works, at least, one and a half times stronger, than for the woman out of pregnancy. Load of all bodies and systems raises not since then as the placenta is formed and the third circle of blood circulation forms, and from the moment of conception. The increased intensity of work of an organism is followed by development of surplus of metabolites. Therefore emergence in analyses of acetone at pregnancy is possible on any term. Normal ketonic bodies (simply, acetone) appear in cells as necessary elements of feedback by means of which cells signal about a lack of glucose. As soon as there is an acetone at pregnancy, to the central nervous system there is a signal that the additional mechanism of development of energy turned on. The way of neoglucogenesis reserve, also works it in extreme situations. The fact that the woman bears the child is not pathology therefore emergence of acetone at pregnancy demonstrates exchange disturbances.

Normal incubation of an embryo provides an additional metabolic cost for formation of bodies of a fruit. Carbohydrates, proteins, mineral substances are spent. Fatty tissues are connected to a metabolism when the stock of a glycogen and the mobile proteins circulating in blood comes to an end. When splitting of fatty acids begins, a significant amount of intermediate products of biochemical reaction – ketones appears. In normal conditions they are right there processed in a cell with receiving additional molecules ATP. When the amount of ketones becomes critical, reserves of intracellular processing are exhausted, in an organism acetone so appears, at pregnancy it testifies to disbolism. First ketones appear in blood. Some time they are filtered by cells of a liver and neutralized. At further education of intermediate metabolites, the reserve power of hepatic cells becomes insufficiently, then there is an acetone in urine at pregnant women that is an important diagnostic character.

Acetone in urine at pregnant women

The certificate on what in an organism was earned by an energy development side-track, this emergence of acetone at pregnancy in analyses of urine. The following states can serve as the reasons of pathology:

• Alcoholism, both acute poisoning with alcohol, and chronic;
• Hobby for fasting days for the purpose of weight reduction;
• Infectious diseases;
• Condition of a chronic stress;
• The increased body temperature.

Under the influence of alcohol it is disconnected additional (not reserve!) a way of development of energy – anaerobic. It leads to release of a small amount of energy and several molecules of alcohol which call endogenous. As the additional way is blocked, immediately joins reserve – neoglucogenesis. As a result there is in an organism an acetone, at pregnancy when the liver works at full capacity, ketonic bodies without processing come to blood. Then they are brought with urine as potentially dangerous elements.

Fasting days are appointed at a pathological increase of weight, for the purpose of identification of the obscure edemas. When the pregnant woman excludes flour, sweet products from a diet, there is a deficit of glucose in blood. Naturally, neoglucogenesis process is started.

Infectious agents: bacteria, viruses, protozoa and parasites – demand an additional metabolic cost, not only for providing immune responses, but also that is called for own use. Cellular membranes of microbes consist of polysaccharides, and at reproduction, they include the glucose circulating in blood of the person in the structure. Start of the mechanism of neoglucogenesis provokes emergence in acetone blood at pregnancy therefore infectious diseases are followed by a ketonuria.

Stressful reactions are followed by emission of hormones – glucocorticoids. Their name speaks for itself: "causing a gluconeogenesis". So at injuries, exercise and psychological stresses acetone appears, at pregnancy it comes to light at once as women to each dispensary appearance make the general tests of urine.

The mechanism of formation of acetone at pregnancy at the increased body temperature is explained by emergence in blood of the pyrogenic substances which neutralization also requires additional energy.

The raised acetone at pregnancy

Ketones or acetone (these are synonyms) in blood tests and urine should not be defined in any quantities. Education and neutralization of intermediate metabolites normal comes to the end at the level of cells therefore, so far as concerns the raised acetone at pregnancy, it is meant or its existence in analyses of urine, or the increased quantity in dynamics.

As reaction to acetone qualitative, results of analyses are noted by the sign "+", with a growth of amount of ketones two and three pluses are put. The lowest border is noted as "acetone traces".

At treatment of a ketonuria steady falling of amount of acetone is considered positive dynamics, at pregnancy its emergence is dangerous to a fruit brain. Therefore at identification of "traces of ketonic bodies" in urine additional inspection in the conditions of a hospital is necessary.

Acetone smell at pregnancy

The expressed ketonuria form, as a rule, accompanies the following complications:

• Heavy degree of toxicosis;
• Progressing of a gestosis to a preeclampsia stage;
• Diabetes mellitus debut.

The increased content of ketones in blood leads to emergence of a smell of acetone at pregnancy which is not similar to evaporations of chemical solvent with the same formula at all. It is a smell of baked or soaked apples. The reason of its emergence – secretory function of lungs. In such cases inspection in a hospital is also recommended.