Adapalen
Application instruction:
Adapalen – local drug for therapy of an acne, has antiinflammatory and komedonolitichesky activity, normalizes process of keratinization (a specific differentiation of epidermal cells).
Form of release and structure
Dosage form of Adapalen – gel for external use of 0,1%: substance of white color (on 15 or 30 g in plastic tubas, in a cardboard pack 1 tuba).
In 100 g of gel contains:
- Active ingredient: адапален – 0,1 g;
- Auxiliary components: propylene glycol, карбопол (carbomer), dinatrium эдетат, phenoxyethanol, sodium hydroxide, methylparaben, half-oxameasures, the water purified – to 100 g.
Indications to use
Adapalen gel is recommended to use for therapy of acne rash.
Contraindications
Absolute:
- Pregnancy and period of breastfeeding (lactation);
- Children's age up to 12 years;
- The increased individual sensitivity to gel components.
Relative (gel is applied with care because of the increased probability of complications): seborrhea, dermatitis, eczema.
Route of administration and dosage
Gel is applied outwardly, once a day (for the night), on previously cleared dry skin, evenly distributing light touches and avoiding hit of drug on lips and in eyes.
Considerable clinical improvement occurs 4-8 weeks later from the beginning of use of gel, the resistant result is observed after 3 months of therapy.
Side effects
The peeling and hyperemia of integuments in the place of application of Adapalen is possible.
Special instructions
It is necessary to avoid stay in the sun, and at the planned long stay gel cannot be applied on the sun a day before it, in day of solar exposure and next day.
It is not recommended to use along with Adapalen cosmetics with the irritating and drying action on skin (for example, with the ethanol content).
In case of irritation of integuments it is necessary to interrupt therapy for a while or to completely stop gel use.
Medicinal interaction
Simultaneous use of an adapalen from benzoyl is allowed by peroxide or clindamycin.
It is necessary to be careful in case of combined use of gel with the drugs drying or irritating skin, including containing Resorcinolum, sulfur or salicylic acid as they can strengthen side effects.
Terms and storage conditions
To store at a temperature up to 25 °C, in unavailable to children, the dry, dark place.
Period of validity – 2 years.
Blood of the person "runs" on vessels under huge pressure and at disturbance of their integrity is capable to shoot of distance to 10 meters.
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