Angiozil ретард
Application instruction:
Angiozil ретард – the medicine of group of antigipoksant improving utilization of the oxygen circulating in an organism, and increasing resistance to oxygen insufficiency (hypoxia), influencing directly neurons of a brain and cardiomyocytes, optimizing their metabolism and function.
Form of release and structure
Dosage form of Angiozil ретард – tablets of the prolonged action, coated: biconvex, round, a cover of pink color (on 10 or 14 pieces in a blister strip packaging, in a cardboard pack of 3 or 6 packagings on 10 pieces or 2 or 4 packagings on 14 pieces).
In 1 tablet of the prolonged action, coated, contains:
- active ingredient: a trimetazidina dihydrochloride – 35 mg;
- auxiliary components: gipromelloza, magnesium stearate, silicon dioxide colloid, cellulose microcrystallic, опадрай II (lactoses monohydrate, gipromelloz, triacetin, titanium dioxide, macrogoal, ferrous oxide yellow and red).
Indications to use
- Ischemic heart disease (coronary heart disease) – as a part of complex therapy for prevention of attacks of stenocardia;
- kokhleovestibulyarny disturbances of the ischemic nature (sonitus, dizziness, hearing disorder);
- chorioretinal vascular pathologies.
Contraindications
- lactose intolerance, deficit of lactase, syndrome of glyukozo-galaktozny malabsorption;
- renal failures (clearance of creatinine of ≤15 ml/min.);
- the expressed liver failure;
- period of pregnancy and lactation (breastfeeding);
- children's and teenage age up to 18 years (the profile of efficiency and safety for this age group was not investigated);
- hypersensitivity to drug components.
Route of administration and dosage
Pill Angiozil ретард is taken inside.
The recommended dosing mode (if there are no other instructions): on 1 piece (35 mg) 2 times a day, in the morning and in the evening, during meal.
Duration of a course of treatment is established for each patient individually.
Side effects
Frequency of the side effects observed at reception of a trimetazidin from bodies and systems (according to gradation: very often –> 1/10; often –> 1/100-<1/10; infrequently –> 1/1000-<1/100); seldom –> 1/10 000-<1/1000); very seldom – <1/10 000 (including separate messages)):
- alimentary system: often – diarrhea, dyspepsia, an abdominal pain, nausea, vomiting;
- central nervous system: often – a headache, dizziness, an adynamy; very seldom – extrapyramidal frustration (rigidity, a tremor, an akineziya) (these reactions are reversible and pass after drug withdrawal);
- integuments: often – urticaria, an itch, skin rash;
- cardiovascular system: seldom – orthostatic hypotension, rushes of blood to face skin.
Special instructions
Trimetazidin do not apply to stopping of attacks of stenocardia, at development of heart attack therapy is recommended to be reconsidered and adapted.
Do not use drug in an initial course of treatment of a myocardial infarction or unstable stenocardia.
Owing to lack of these clinical trials of use of drug at heavy abnormal liver functions, it is not recommended to appoint antigipoksant of this category of patients.
Angiozil ретард on ability to driving of motor transport and performance of work, demanding increased concentration of attention and speed of psychomotor reactions, influences slightly.
Medicinal interaction
Information on interaction of a trimetazidin with other medicinal substances / drugs is absent.
Terms and storage conditions
To store in the dry, dark place at a temperature not above 25 °C. To protect from children.
Period of validity – 3 years.
Name of drug
Price
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