Azitsid – an antibiotic of a broad spectrum of activity from group of azaleads (subgroup of macroleads), active concerning some gram-positive cocci, streptococci, gram-negative bacteria, anaerobic microorganisms; it is not effective at the diseases caused by the gram-positive bacteria steady against erythromycin.
Dosage form – tablets, coated: white color, round biconvex – 250 mg; white color, oblong shape – 500 mg (on 3 pieces in the blister, in a pack cardboard 1 or 2 blisters).
Contains in 1 tablet:
Azitsid is applied to treatment of the diseases caused by microorganisms, sensitive to azithromycin:
Relative (it is required to be careful at administration of drug):
Azitsid it is necessary to accept in 1 times a day, between meals – in 1 hour prior to food or in 2 hours later.
The recommended dosing modes for adults:
The dose for children is defined depending on their weight: on 10 mg/kg of 1 times a day within 3 days or 10 mg/kg in the first day, for the next 3-4 days – on 5-10 mg/kg/days.
At an erythema to children appoint creeping: the 1st day – 20 mg/kg, 2-5 days – on 10 mg/kg.
In case of the admission of the next reception it is necessary to accept the passed dose as soon as possible, and the subsequent – with 24-hour intervals.
At co-administration of antacids between administrations of drugs it is necessary to observe a break of ≥2 hours.
At some patients after Azitsid's cancellation hypersensitivity reactions which demand performing specific therapy under medical control can remain.
The food, ethanol and antacids containing magnesium or aluminum slow down and reduce azithromycin absorption.
Linkozamina reduce Azitsid's efficiency, tetracycline and chloramphenicol – increase.
Azithromycin at simultaneous use increases concentration of digoxin, strengthens toxic effect of ergotamine and dihydroergotamine, reduces clearance and strengthens pharmacological action of a triazolam.
Azithromycin slows down removal, than increases concentration in a blood plasma and toxicity of the following medicines: indirect anticoagulants, фелодипин, Cycloserinum, Methylprednisolonum, and also the drugs which are exposed to a microsomal oxidation such as ergot alkaloids, peroral hypoglycemic means, valproic acid, терфенадин, hexobarbital, Bromocriptinum, Disopyramidum, Phenytoinum, cyclosporine, carbamazepine, theophylline and other ksantinovy derivatives.
As macroleads strengthen anticoagulating effect of warfarin, the similar effect can be expected also at simultaneous use of azithromycin therefore at use of this combination it is necessary to control a prothrombin time.
To store at a temperature up to 25 °C. To protect from children.
Period of validity – 2 years.
At regular visit of a sunbed the chance to develop a carcinoma cutaneum increases by 60%.
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