Furacilin

Furacilin – antibacterial and antiprotozoan agent for external and topical administration.

Pharmacological action

Active component of Furacilin has antimicrobic effect.

Unlike other chemotherapeutic means, Furacilin possesses other mechanism of action and forms the high-reactive amin derivatives causing conformational changes of proteins of macromolecules that leads to death of cells.

Furacilin is active concerning the majority of gram-positive and gram-negative bacteria, for example:

• Streptococcus spp.;
• Salmonella spp.;
• Staphylococcus spp.;
• Shigella (flexneri spp., dysenteria spp., boydii spp., sonnei spp.);
• Clostridium perfringens;
• Escherichia coli.

Stability to active component of Furacilin develops slowly and, as a rule, does not reach high degree. Besides, means promotes increase in activity of reticuloendothelial system and strengthening of phagocytosis.

Form of production of Furacilin

The drug Furacilin is produced in a look:

• Spirit 0,067% of solution for topical and external use, in bottles on 10 and 25 ml;
• Tablets for preparation of solution for topical administration, on 20 and 100 mg;
• Solution of 0,02% for topical and external use, in bottles on 200 and 400 ml;
• Pastes for external use, on 1 and 2 kg;
• Ointments of 0,2% for topical and external use, on 25 g.

Analogs of Furacilin are the following medicines:

• On active agent – Lifuzol, Furaplastum, Furatsilin-Lekt;
• On a way of action – Combutecum-2.

Indications to Furacilin use

According to the instruction Furacilin is appointed outwardly at treatment:

• Decubituses;
• Purulent wounds;
• Small injuries of skin, including scratches, grazes, cuts and cracks;
• Freezing injuries of the II-III degree;
• Burns of the II-III degree.

Locally Furacilin according to the instruction is applied at:

• Conjunctivitis;
• Ulitis;
• Blepharitis;
• To empyema of a pleura and adnexal bosoms of a nose;
• Osteomyelitis;
• Acute outside and average otitis;
• Infections of urinary tract;
• Stomatitis;
• Acute tonsillitis.

Contraindications

Use of Furacilin is contraindicated in the following cases:

• At bleedings;
• Against the background of the existing allergodermatoz;
• At hypersensitivity to Furacilin components.

Furacilin route of administration

According to indications Furacilin can be used in various dosage forms.

At treatment of a blepharitis and conjunctivitis Furacilin according to the instruction is applied:

• Aqueous solution – in the form of instillation in a conjunctival sac;
• Ointment – for greasing of edges a century.

Furacilin of a mouth and throat recommends to apply the solution received from one tablet dissolved in 100 ml of water to rinsing.

Furacilin in the form of ointment is applied to treatment of burns and freezing injuries of the I-II degree, and also mucous membranes and superficial wounds of skin. Use duration – up to three days.

Use of Furacilin in the form of spirit solution (on 5-6 drops) is effective at treatment of otitises. Before use solution should be warmed to body temperature. Means is recommended to be used daily before disappearance of symptoms of a disease.

Outwardly it is possible to apply both spirit, and aqueous solution of Furacilin to irrigation of wounds and imposing of water dressings.

Washing by Furacilin effectively at an empyema of adnexal bosoms of a nose, including antritis what apply the ready or prepared from tablets aqueous solution to.

Besides, washing by Furacilin effectively:

• At osteomyelitis after operation (with the subsequent imposing of water dressing);
• For washing of a bladder and an urethra (with exposure by aqueous solution for 20 minutes);
• After removal of pus at a pleura empyema (with use of aqueous solution in number of 20-100 ml for washing of a pleural cavity).

Side effects of Furacilin

At use of Furacilin according to indications dermatitis and allergic reactions in certain cases can develop.

Storage conditions

According to indications Furacilin is released from drugstores without medical appointment. A drug period of storage – up to two years (at observance of requirements to storage).