Ginepriston

Kliniko-pharmakologichesky group

Ginepriston – drug which belongs to group of gestagen and also is among the emergency contraceptives.

Release form, packaging and Ginepriston's list

The analyzed means is issued in ploskotsilindrichesky tablets (1 tablet contains 10 mg of mifepristone), which color passes from light yellow to a greenish shade.

It is possible to carry microcrystallic cellulose, calcium stearate, and also sodium carboxymethylstarch to auxiliary components of Ginepriston.

In drugstores it is released in strip planimetric packagings or cardboard boxes in number of 1-2 pieces. Also medicine is sold in polymeric banks in which there are also 1 or 2 tablets.

Pharmacological action of Ginepriston

In the instruction to Ginepriston it is accurately specified that this drug is intended for the emergency prevention of approach of pregnancy. The main operating component of such means is mifepristone.

Mifepristone possesses such chemical structure which Ginepriston allows to carry to synthetic steroid means (at the same time it should be noted that adrenal glands are responsible for production of the sterodny hormones which are in a human body).

Ginepriston's action consists in blocking of receptors of progesterone (the main women's hormone which is responsible for successful and correct pregnancy). In a uterus the bad environment for fertilization of an ovum, and also its impossible attachment to uterus walls is caused by similar processes. In the instruction to Ginepriston it is noted that this drug also slows down maturing of an ovum (ovulation). To understand pharmacological action of Ginepriston, it is necessary to remember what represents process of an ovulation. First of all, this release of an ovum from completely ready, mature follicle of an ovary to prepare it for passing to a fallopiyeva a pipe (oviduct). In an oviduct also there occurs fertilization. An ovulation – continuous, monthly process which happens every 19-45 days. Accepting Ginepriston, process of an ovulation is slowed down. Also in a uterus unfavorable conditions for fertilization which are shown in a slime condensation on a neck of uterus, and also the changes concerning a functional layer of a uterus are created. Thus, Ginepriston for abortion is very effective and well-tried remedy.

Indications to Ginepriston's use

The instruction to Ginepriston contains detailed information which will prompt that this drug should be accepted as means of an emergency contraception. Ginepriston will help to protect the woman from unplanned pregnancy right after the unprotected sexual intercourse.

As it is told in responses to Ginepriston to achieve the most positive take, it is necessary to take one pill of means right after sexual intercourse or not later than in 72 hours after it. Also in responses to Ginepriston it is noted that it is the best of all to accept means in 2 hours prior to food or in 2 hours after it.

Contraindications

In the instruction to Ginepriston a number of contraindications with which surely it is necessary to get acquainted before beginning to use this means is specified.

1. It is not necessary to accept drug if insufficiency of function of adrenal glands, kidneys and a liver is found in the woman.

2. In responses to Ginepriston the undesirable use of drug by that to persons who have chronic diseases is specified or throughout a long time accepted Prednisolonum, a hydrocortisone or dexamethasone.

3. At detection of any serious illness Ginepriston is also not recommended to accept.

4. Additional consultation at the specialist is necessary also when the woman has problems with a cordial rhythm if heart failure or disturbance of coagulability of blood is found.

5. Ginepriston for abortion it is not necessary to accept if previously the woman used medicines which active ingredient was directed to blood coagulation process.

6. It is not necessary to accept Ginepriston together with nonsteroid means which action is directed to elimination of process of an inflammation (indometacin, analginum, paracetamol, aspirin, etc.).

Having completed to accept Ginepriston, feeding process by a breast should be continued only after 14 days.

Ginepriston's dosage

Ginepriston it is necessary to use orally in 72 hours after completion of the unprotected sexual intercourse.

Ginepriston for abortion will work most effectively if in 2 hours prior to administration of drug is not and not to drink, and also to refrain from meal within 2 hours after its use.

In responses to Ginepriston it is specified that drug does not influence a menstrual cycle therefore it is possible to accept it when necessary.

Side effects of Ginepriston

The most widespread side effects after Ginepriston's reception are nausea, pain in the bottom of a stomach, dizziness, a headache, vomiting, bloody allocations, skin rashes, temperature increase, weakness, disturbance of a menstrual cycle.

Reviews of Ginepristona say about what after administration of drug of strongly expressed side effects practically never happens.

Before getting Ginepriston in drugstores, it is necessary to consult in addition at the qualified gynecologist.

Overdose by Ginepriston

For a human body Ginepriston's reception in volume to 2 g is considered safe.

The overdose is resulted sometimes by adrenal insufficiency. At the same time it is recommended to conduct the corresponding course of treatment.

Pregnancy period

During pregnancy Ginepriston it is strictly forbidden to accept.

The period of a lactation can be renewed only after 2 weeks after the drug use.

Storage conditions

The period of validity of drug makes no more than 3 years. It is necessary to store it in the dry, protected from light place at a temperature up to 30 degrees.

Special instructions

Ginepriston for abortion cannot be a constant contraceptive.

The analyzed means will not protect the woman from AIDS and other diseases, sexually transmitted.