Tablets, coated: round, with a white kernel and a plain brilliant surface, white (20 + 50 + 60 mg) or orange (60 + 100 + 60 mg) colors (on 10 pieces in blisters, on 3 (20 + 50 + 60 mg) or 5 (60 + 100 + 60 mg) blisters in a cardboard pack);
Solution for intravenous and intramuscular administration: colourless, transparent (on 2 ml in ampoules, on 5 ampoules in blister strip packagings, on 1 packaging in a cardboard pack).

Active agents are a part of 1 tablet:

Hexobendinum dihydrochloride – 20/60 mg;
Etamivan – 50/100 mg;
Etofillin – 60/60 mg.

Auxiliary components: magnesium stearate – 2/3 mg; prezhelatinizirovanny starch – 7,67/17,12 mg; talc – 4/8 mg; monohydrate of lactose – 10/12 mg; corn starch – 36,33/29,88 mg.

Cover: K30 povidone – 1,2/1,4 mg; glycolic mountain wax – 0,1/0,1 mg; a macrogoal 6000 – 2,4/2,8 mg; acacia gum – 4,75/5,6 mg; sucrose – 34,33/39,3 mg; talc – 26,75/28 mg; titanium dioxide – 0,47/1,4 mg; in addition for tablets 60 + 100 + 60 mg: dye yellow "Sunset" – 1,4 mg.

The structure of 1 ampoule (2 ml) of solution for intravenous and intramuscular administration includes active agents:

Hexobendinum dihydrochloride – 10 mg;
Etamivan – 50 mg;
Etofillin – 100 mg.

Auxiliary components: propylene glycol – 416 mg, эдетат dinatrium – 0,08 mg, water for injections – to 2 ml.

Indications to use

The brain diseases having vascular genesis and connected with age changes;
Postinsultny states;
The dizzinesses connected with functional disorders of a brain;
Effects of insufficiency of brain blood supply.

Contraindications

Convulsive syndrome;
Condition of strong excitement;
Symptoms of the increased intracranial pressure (vomiting, long headache, vision disorders);
Hematencephalon;
Epilepsy;
Hypersensitivity to drug components.

Care is demanded by Instenon's use after recently had stroke and at a stenosis of a carotid artery owing to arteriosclerosis.

The feeding and pregnant women can use drug only according to strict indications.

Route of administration and dosage

Instenon in the form of tablets accept inside, in time or after food, without chewing and washing down with liquid in a small amount.

Depending on indications drug is appointed by 3 times a day on 1-2 tablets (20 + 50 + 60 mg) or on 1 tablet (60 + 100 + 60 mg). In case of need a daily dose it is possible to increase to 5 tablets (60 + 100 + 60 mg), divided into several receptions.

Duration of therapy has to make not less than 6 weeks.

Instenon in the form of solution for injections enter intramusculary or intravenously kapelno or slowly.

Depending on weight of a state the drug is administered by 1-2 times a day on 1 ampoule (intramusculary or intravenously slowly or in the form of drop infusion from 5% glucose solution (250 ml)). After improvement of a state therapy can be continued by Instenon's reception inside in the form of tablets, coated.

At bystry administration of solution at some patients the arterial pressure in this connection duration of intravenous administration of 1 ampoule has to make not less than 3 minutes can go down.

Side effects

In some cases during use of high doses of Instenon can decrease arterial pressure, develop a hyperemia of the person and a headache.

Special instructions

During Instenon's use it is necessary to be careful when performing potentially dangerous types of the works requiring special attention and bystry psychomotor reactions.

Medicinal interaction

At simultaneous use of Instenon with the drugs reducing activity of thrombocytes (including acetylsalicylic acid), strengthening of antiagregantny action is possible (it is caused by influence of Hexobendinum).

Decrease in efficiency of Instenon it can be observed at use of high doses of caffeine (it is recommended to avoid the use of tea and coffee in large numbers).