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Ekstentsillin

Ekstentsillin is the natural Экстенциллин во флаконахantibiotic of a penicillinic row received from mold mushrooms of Penicillium chysogenum.

Pharmacological action

According to the instruction Ekstentsillin has bactericidal effect on microbic cells. Drug possesses rather long action. It is effective concerning gram-positive (Corynebacterium diphtheriae, Streptococcus pneumoniae, Staphylococcus spp), gram-negative (Neisseria meningitidis, Neisseria gonorrhoeae) and anaerobic spore-forming (Actinomyces israelii, Clostridium spp., Bacillus anthracis) bacteria. Also to Ekstentsillin possesses a high susceptibility of Treponema spp.

In the instruction to Ekstentsillin it is noted that the strains of bacteria producing (developing) a penicillinase – substance Staphylococcus spp destroying Benzilpenitsillin, for example are steady against this medicine.

Indications

  • The diseases caused by pale treponemas including syphilis;
  • The infectious diseases caused by streptococci (except group B streptococci) – an erysipelatous inflammation, scarlet fever, tonsillitis;
  • Treatment of wound complications which development is caused by the microflora sensitive to this drug.

According to the instruction Ekstentsillin can be also used for prevention of an exacerbation of rheumatism and prevention of purulent postoperative complications.

Contraindications

  • Hay fever;
  • Bronchial asthma;
  • Individual hypersensitivity.

Drug is contraindicated also for treatment of patients in whose anamnesis there is an instruction on intolerance beta лактамных antibiotics (Penicillin, Cephalosporin, etc.).

Side effects

According to the instruction Ekstentsillin can result in the following side effects:

  • Acute anaphylaxis;
  • Hay fever;
  • Small tortoiseshell;
  • Quincke's disease (Quincke's edema);
  • Arthralgia;
  • Exfoliative dermatitis;
  • Multiformny exudative erythema;
  • Headache;
  • Glossitis;
  • Stomatitis;
  • Leukopenia, thrombocytopenia, anemia;
  • Hypocoagulation.

At prolonged Аналог Экстенциллинаtreatment by Ekstentsillin the superinfection caused by mushrooms or microbic flora, steady against action of an antibiotic, can develop.

Application instruction

The drug is administered deeply intramusculary. The adult for prevention of an exacerbation of rheumatism appoint 2400000 PIECES once in 15 days. For treatment of syphilis Ekstentsillin enter once in eight days on 2400000 Units appoint 2 – 3 injections to a course of treatment.

The dosage for children depends on their age and body weight (from 600000 to 1200000 PIECES).

Special instructions

At emergence of allergic reactions treatment by Ekstentsillin should be stopped immediately. It is strictly forbidden to administer this medicine intravenously, subcutaneously, endolyumbalno or in a perigastrium. At accidental introduction of Ekstentsillin to a gleam of a blood vessel Uanye's syndrome which is shown a vision disorder, feeling of alarm and depression can develop.

According to the instruction Ekstentsillin it is necessary to appoint along with vitamins of group B and ascorbic acid that he allows to reduce risk of development of fungal superinfection. If necessary to the patient also antifungal medicines (Levorin, Nistatin) can be appointed.

Ekstentsillin's analogs

Similar action with this drug Bicillinum-1 possesses. It is Ekstentsillin's analog. However a dosage at this medicine other. Therefore before using Ekstentsillin's analog it is necessary to consult with the specialist.

Dosage form

Ekstentsillin is issued in the form of the lyophilized powder in sterile bottles. Powder just before an injection gets divorced in aseptic conditions water for injections.

Storage conditions of Ekstentsillin

Ekstentsillin store in the place, dry and unavailable to children, protected from hit of direct sunshine at the room temperature.

 
 
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