The prices in Internet drugstores:
from 115 rub.
L-thyroxine – thyritropic drug, hormone of a thyroid gland.
Medicine is produced in the form of tablets (on 10 pieces in blister strip packagings, on 2, 3, 4, 5, 6, 8 or 10 packagings in a cardboard pack; on 20 or 50 pieces in polymeric containers, on 1 container in a cardboard pack; on 50 pieces in blister strip packagings, on 1, 2, 4, 5, 6, 8 or 10 packagings in a cardboard pack; on 50 pieces in blisters, on 1 blister in a cardboard pack).
1 tablet contains active agent: sodium left thyroxine – 50 or 100 mkg.
Relative (drug needs to be taken with caution):
The overdose of L-thyroxine is shown by the symptoms characteristic of a thyrotoxicosis: disturbance of a heart rhythm, heartbeat, heartaches, tremor, concern, sleep disorder, increase in appetite, hyperhidrosis, diarrhea, weight reduction. The doctor can recommend (depending on symptomatology): decrease in a daily dose of drug, several days of a break in treatment, purpose of β-adrenoblockers.......... Therapy should be continued with care after passing of side effects from lower dose.
Pill is taken inside in the morning on an empty stomach, at least in 1/2 hours prior to meal, without chewing and washing down with a small amount (1/2 glasses) of water.
The daily dose of L-thyroxine is defined by the attending physician individually and depends on indications.
For performing replacement therapy of a hypothyroidism at patients 55 years, in case of absence of cardiovascular diseases, the recommended daily dose of L-thyroxine – 1,6-1,8 mkg/kg of body weight are younger. To patients 55 years are more senior or in the presence of cardiovascular diseases the dose is defined at the rate of 0,9 mkg/kg of body weight. Calculation is made by the patient with a gross obesity (IMT – a body weight index ≥ 30 kg/sq.m) on "the ideal weight".
At the initial stage of replacement therapy at a hypothyroidism the recommended left thyroxine dose:
In case of emergence or aggravation of symptoms from cardiovascular system it is necessary to carry out correction of a course of treatment of cardiovascular diseases.
The recommended daily doses of L-thyroxine for therapy of an inborn hypothyroidism, depending on age of the child (a dose a left thyroxine left thyroxine/dose per body weight):
The recommended daily doses of L-thyroxine depending on a state/disease:
Children from the birth and up to 3 years a daily dose of left thyroxine are given in 1/2 hours prior to the first feeding (in one step). Just before use the tablet needs to be dissolved in water before formation of a thin suspension.
In case of a hypothyroidism L-thyroxine is accepted, as a rule, throughout all life. For treatment of a thyrotoxicosis medicine is used in a complex with anti-thyroid drugs after achievement of an euthyroid state. Duration of a course of therapy by left thyroxine at any states / diseases is defined by the attending physician.
At use of L-thyroxine with observance of all recommendations and under medical control side effects were not noted.
In case of hypersensitivity to left thyroxine allergic reactions are possible. Other side effects can develop only at drug overdose.
In case of the hypothyroidism caused by damage of a hypophysis it is necessary to carry out diagnosing and to find out whether there is no insufficiency of bark of adrenal glands at the same time. At a positive take it is necessary to begin replacement therapy of GKS (glucocorticosteroids) before reception of thyroid hormones for treatment of a hypothyroidism to avoid development of acute adrenal insufficiency.
Periodically it is necessary to control concentration of TTG in blood, increase in this indicator speaks about insufficiency of a dose of L-thyroxine.
Left thyroxine does not influence concentration of attention and speed of the psychomotor reactions necessary for control of difficult mechanisms and vehicles.
Mutual influence of the following substances / drugs and left thyroxine at simultaneous use:
To store in dry, protected from light, the place, unavailable to children, at a temperature not above 25 °C.
Period of validity – 3 years.
Name of drug
L-thyroxine таб. 100 mkg of n50
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