Lerkamen

Lerkamen – the blocker of slow calcium channels applied at treatment of diseases of cardiovascular system.

Pharmacological action of Lerkamen

Drug Lerkamen inhibits cells of smooth muscles of vessels and transmembrane current of calcium in cardiomyocytes, possesses the prolonged anti-hypertensive action and hypotensive effect, thanks to the direct running-down action on unstriated muscles of vessels.

Form of release of Lerkamen

According to the instruction, Lerkamen release in the form of biconvex, round, film coated pale yellow or light yellow color of tablets, with risky on one of the parties, light yellow color on a break, in blisters, in packs cardboard. One tablet of Lerkamen contains 10 mg of a lerkanidipin of a hydrochloride, 30 mg of lactose of monohydrate, 39 mg of cellulose of microcrystallic, 15,5 mg of carboxymethylstarch of sodium (type A), 4,5 mg of K30 povidone and 1 mg of magnesium of stearate.

3 mg opadry OY-SR-6497, 1,913 mg of a gipromelloza, 0,3 mg of a macrogoal 6000, 0,15 mg of talc, 0,6 mg of titanium of dioxide and 0,037 mg of dye of ferrous oxide yellow are a part of a film cover of Lerkamen.

Also according to the instruction, Lerkamen release in the form of biconvex, round, film coated tablets of reddish-pink color, with risky on one of the parties, light yellow color on a break, in blisters, in packs cardboard. One tablet of Lerkamen contains 20 mg of a lerkanidipin of a hydrochloride, lactose monohydrate, cellulose microcrystallic, sodium carboxymethylstarch (type A), K30 povidone and magnesium stearate.

Dioxide, macrogoal 6000, iron oxide, talc and gipromelloza is a part of a film cover of Lerkamen опадрай 02F25077, titanium.

Lerkamen's analogs

Lerkamen's analog on active ingredient are Zanidip-Rekordati's drug.

On the mechanism of action and belonging to one pharmacological group carry medicines to Lerkamen's analogs:

• Agin;
• Vero-Amlodipin;
• Zanifed;
• Kardilopin;
• Latsipil;
• Nimopin;
• Omelar кардио;
• Plendil;
• Oriental cherries;
• Tinox;
• Foridon;
• Eskordi Kor.

Indications to Lerkamen's use

According to the instruction, Lerkamen appoint at essential hypertensia of easy and moderate severity.

Lerkamen route of administration

According to the instruction, Lerkamen accept in 15 minutes prior to meal of morning in, without chewing and plentifully washing down with water. The initial dose of drug makes 10 mg with gradual increase up to 20 mg once a day.

Contraindications

According to the instruction, Lerkamen is contraindicated to use at:

• Hypersensitivity to drug components;
• Aortal stenosis;
• Lactose intolerance, galactosemia, syndrome of the broken absorption of glucose and a galactose;
• Chronic heart failure;
• The expressed abnormal liver functions and kidneys;
• Unstable stenocardia.

Also Lerkamen's use is contraindicated at pregnancy and in the period of a lactation, for a month after the postponed myocardial infarction, to children aged up to 18 years and to the women of childbearing age who are not using reliable contraception.

With care Lerkamen appoint at a liver and renal failure, to patients of advanced age, coronary heart disease and dysfunction of a left ventricle.

Side effects of Lerkamen

Lerkamen's use, according to reviews, causes side effects from various systems of an organism, namely:

• Peripheral hypostases, heartbeat, tachycardia, lowering of arterial pressure, stethalgia, stenocardia, adynamy, myocardial infarction, fatigue, headache and dizziness (cardiovascular system);
• Dyspepsia, vomiting, reversible increase in activity of liver enzymes, pain in epigastriums, nausea, diarrhea and a hyperplasia of gums (alimentary system).

Also Lerkamen, according to reviews, sometimes causes a polyuria, skin rash, a mialgiya and drowsiness.

Storage conditions

According to the instruction, Lerkamen it is necessary to store in the unavailable to children and protected from light hit, dry place, at the room temperature up to 30 °C. The medicine period of storage at observance of recommendations makes 3 years.