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Mebendazolum

Таблетки МебендазолMebendazolum – protivogelmintny drug with a broad spectrum of activity, is especially effective at an enterobiosis.

Form of release and structure

Dosage form – tablets (on 6 pieces in a blister strip packaging, in a cardboard pack 1 packaging).

Active agent – Mebendazolum, in 1 tablet – 100 mg.

Indications to use

Use of Mebendazolum is shown at treatment of the mixed helminthoses, an enterobiosis, an ankilostomidoz, an ascaridosis, a strongyloidosis, a trichinosis, a trichuriasis, a teniosis, an alveococcosis, a kapillyarioz, an echinococcosis, a gnatostomoz.

Contraindications

  • Heavy abnormal liver functions;
  • Period of pregnancy and breastfeeding;
  • Age up to 2 years;
  • Individual intolerance of Mebendazolum.

Route of administration and dosage

Pill is taken orally.

The recommended dosing:

  • Enterobiosis (use of tablets by all family members at the same time is necessary): patients of 10 years are also more senior – 100 mg, children from 2 to 10 years – 25-50 mg once. For an exception of a repeated invasion in 2-4 weeks it is recommended to repeat reception in the same dose;
  • The mixed helminthoses, ascaridosis, анкилостомидоз, a trichuriasis, a strongyloidosis, a teniosis: on 100 mg 2 times a day (in the morning and in the evening), a course of treatment – 3 days;
  • Trichinosis: on 200-400 mg 3 times a day during the first 3 days, then on 400-500 mg 3 times a day during the next 7 days;
  • Echinococcosis: on 500 mg with frequency rate of reception in the first 3 days of therapy 2 times and in the next 3 days – 3 times a day. Further treatment is continued in the daily dose corresponding of 25-30 mg on 1 kg of weight of the patient divided into 3-4 receptions.

Side effects

  • Nervous system: at high doses against the background of long therapy – a headache; seldom – dizziness;
  • Alimentary system: seldom – abdominal pains, nausea; at high doses against the background of long therapy – diarrhea, vomiting, tranzitorny increase in activity of liver enzymes in blood serum;
  • Urinary system: at high doses against the background of long therapy – a hamaturia, a cylindruria;
  • System of a hemopoiesis: at high doses against the background of long therapy development of anemia, a leukopenia, an eosinophilia is possible;
  • Others: at high doses against the background of long therapy – a hair loss, development of allergic reactions.

Special instructions

Prolonged use of Mebendazolum needs to be accompanied with careful control of indicators of function of kidneys and a liver, peripheral blood.

Alcohol intake within 24 hours from the moment of reception of tablets is contraindicated.

It is impossible to apply laxative in combination with Mebendazolum.

After the end of use of drug periodic carrying out laboratory researches a calla and smears of proctal area is required. Efficiency of therapy defines absence at the patient of helminths and their eggs within 1 week after completion of therapy.

Medicinal interaction

Reception of Mebendazolum at a diabetes mellitus causes the need for an insulin dose decline.

Simultaneous use with lipophilic means is not recommended.

Level of maintenance of Mebendazolum in blood at the accompanying therapy by metabolism inductors, including carbamazepine, can decrease, Cimetidinum – to raise.

Terms and storage conditions

To store in the place, unavailable to children, at a temperature up to 25 °C.

Period of validity – 4 years.

 
 
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