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from 24 rub.

Метоклопрамид в таблеткахMetoclopramidum – drug with antiemetic action.

Form of release and structure

Metoclopramidum is released in the following dosage forms:

  • Tablets: ploskotsilindrichesky, round, with a facet, almost white or white, the mramornost is allowed (on 50 pieces in blister strip packagings, on 1 packaging in a cardboard pack; on 10 pieces in blister strip packagings or blisters, on 1-5, 10 packagings or blisters in a cardboard pack; on 14 pieces in blister strip packagings, on 4 packagings in a cardboard pack; on 50 pieces in polymeric or dark glass jars, on 1 jar in a cardboard pack);
  • Solution for intravenous and intramuscular administration (in ampoules on 2 ml, on 5 or 10 ampoules in a cardboard pack or on 5 or 10 ampoules in plastic or strip planimetric packagings (pallets), on 1 or 2 packagings in a cardboard pack).

Is a part of 1 tablet:

  • Active agent: Metoclopramidum hydrochloride – 10 mg (in the form of monohydrate hydrochloride Metoclopramidum in terms of dry matter);
  • Auxiliary components: monohydrate of lactose – 60 mg, the Extra potato starch – 28,47 mg, povidone – 0,53 mg, calcium stearate – 1 mg.

Active agent is a part of 1 ml of injection solution: Metoclopramidum hydrochloride – 5 mg.

Indications to use

  • The nausea, vomiting, hiccups having various etiology (in certain cases Metoclopramidum can be effective at treatment of the vomiting caused by reception of tsitostatik or performing radiation therapy);
  • Functional pyloric stenosis;
  • Meteorism;
  • Hypotonia and atony of a stomach and intestines, including postoperative;
  • Reflux esophagitis;
  • Dyskinesia of biliary tract on hypomotor type;
  • Peptic ulcer of a stomach and duodenum (at an aggravation, along with other medicines).

Also Metoclopramidum is appointed when carrying out X-ray contrast researches of digestive tract (for strengthening of a vermicular movement) and as the means facilitating duodenal sounding (for the purpose of acceleration of gastric emptying and advance of food on a small bowel).



  • Glaucoma;
  • Stomach pyloric stenosis;
  • Bleedings from digestive tract;
  • Perforation of walls of a stomach or intestines;
  • Prolaktinozavisimy tumors;
  • Parkinson's disease;
  • Mechanical intestinal impassability;
  • Pheochromocytoma;
  • Extrapyramidal disturbances;
  • Epilepsy;
  • The vomiting connected with treatment or overdose by neuroleptics and also at patients with cancer of a mammary gland;
  • Bronchial asthma against the background of hypersensitivity to sulfites (injection solution);
  • Deficit of lactase, glyukozo-galaktozny insufficiency, lactose intolerance (tablets);
  • I trimester of pregnancy and period of a lactation;
  • Age up to 2 years (any dosage forms of Metoclopramidum); up to 6 years (injection solution); up to 14 years (tablet);
  • Hypersensitivity to drug components.

Metoclopramidum in any dosage form should not be applied after carrying out operations on digestive tract (an intestines anastomosis, a pyloroplasty) as vigorous muscular contractions interfere with healing.

Relative (Metoclopramidum should be applied with care in the presence of the following diseases / states):

  • Bronchial asthma;
  • Arterial hypertension;
  • Liver and/or renal failure;
  • Children's and elderly (of 65 years) age;
  • II-III trimesters of pregnancy.

Route of administration and dosage

Injection solution:
Metoclopramidum is entered intravenously or intramusculary.

Drug is appointed depending on age:

  • Adults: 1-3 times a day on 10-20 mg (as much as possible – 60 mg a day);
  • Children of 6 years: 1-3 times a day on 5 mg.

In 30 minutes prior to reception of tsitostatik or performing radiation therapy for the purpose of treatment and prevention of nausea and vomiting Metoclopramidum is entered intravenously in a dose of 2 mg/kg of body weight. In case of need in 2-3 hours perhaps repeated administration of solution.

In 5-15 minutes before carrying out X-ray inspection intravenously enter 10-20 mg of Metoclopramidum.

At clinically expressed liver and/or renal failure the dose needs to be reduced twice, the subsequent dose is defined by individual reaction of the patient to therapy.

Metoclopramidum is accepted inside, in 30 minutes prior to meal, washing down with a small amount of water.

Drug is appointed depending on age:

  • Adults: a single dose – 10 mg; as much as possible in days – 30 mg or 0,5 mg on 1 kg of body weight;
  • Children of 14 years: 0,1-0,15 mg on 1 kg of body weight, as much as possible in days – 0,5 mg on 1 kg of body weight.

The maximum duration of therapy – 5 days.

At a renal failure it is necessary to carry out dose adjustment:

  • End-stage (at clearance of creatinine it is less than 15 ml in a minute): 25% of a daily dose;
  • Moderate and heavy stage (at clearance of creatinine of 15-60 ml a minute): 50% of a daily dose.

At a heavy stage of a liver failure the dose should be lowered by 50%.

Side effects

  • Cardiovascular system: atrioventricular block;
  • Central nervous system: extrapyramidal frustration – a lockjaw, a spasm of facial muscles, a spastic wryneck, bulbar type of the speech, a rhythmic protrusion of language, a spasm of extraocular muscles (including okulogirny crisis), a muscular opisthotonos, a hyper tone; parkinsonism (muscular rigidity, a hyperkinesia – manifestation of dofaminblokiruyushchy action, risk of development in children increases at exceeding of a dose of 0,5 mg/kg a day), dyskineses (at a chronic renal failure and at elderly patients), a depression, a headache, drowsiness, uneasiness, fatigue, confusion, a sonitus;
  • Endocrine system: seldom (at long therapy in high doses) – a galactorrhoea, a gynecomastia, disturbance of a menstrual cycle;
  • Alimentary system: diarrhea, lock; seldom – dryness in a mouth;
  • System of a hemopoiesis: a leukopenia, a neutropenia, a sulfhemoglobinemia at adults;
  • Metabolism: porphyria;
  • Allergic reactions: Quincke's disease, bronchospasm, small tortoiseshell;
  • Others: in an initiation of treatment – an agranulocytosis; seldom (at use of high doses) – a hyperemia of a mucous membrane of a nose.

In case of the above described symptoms, their aggravation or development of other side effects it is necessary to see a doctor.

Special instructions

At vomiting of vestibular genesis Metoclopramidum is not effective.

At use of Metoclopramidum data of laboratory indicators of function of a liver and definition of concentration of prolactin and Aldosteronum in plasma can be distorted.

Side effects in most cases develop for 36 hours after use of drug and take place without additional treatment within 24 hours after its cancellation.

Therapy, whenever possible, has to be short-term.

During use of Metoclopramidum it is not recommended to take alcohol.

During treatment it is necessary to be careful during the work with potentially dangerous mechanisms demanding the increased concentration of attention and bystry psychomotor reactions and also at control of motor transport.

Medicinal interaction

At simultaneous use of Metoclopramidum with some medicines there can be following effects:

  • Ethanol: strengthening of action on the central nervous system;
  • Cholinesterase inhibitors: weakening of action of Metoclopramidum;
  • Hypnagogues: strengthening of sedation;
  • Blockers of H2-histamine receptors: increase in efficiency of therapy;
  • Diazepam, tetracycline, ampicillin, paracetamol, acetylsalicylic acid, levodopa, ethanol: increase in absorption;
  • Digoxin, Cimetidinum: absorption delay;
  • Neuroleptics: increase in risk of development of extrapyramidal symptoms.

Before simultaneous use of Metoclopramidum with other medicines it is necessary to consult with the doctor.

Terms and storage conditions

To store in protected from light, the place, dry, unavailable to children, at a temperature up to 25 °C.

Period of validity:

  • Tablets – 2 years;
  • Injection solution – 4 years.
The prices in Internet drugstores:

Name of drug



Metoclopramidum of a tablet 10 of mg of 50 pieces

24 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Metoclopramidum of a tablet of 10 mg 56 pieces

33 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Metoclopramidum тбл 10 mg No. 56, Updating of CJSC PFK

35 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC
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