Main > Drugs> Midriatsil

Midriatsil

Application instruction:

Form of release and structure

Indications to use

Contraindications

Route of administration and dosage

Side effects

Special instructions

Medicinal interaction

Terms and storage conditions

Капли глазные 0,5% Мидриацил Midriatsil – the anticholinergic causing blocking M-holinoretseptorov.

Form of release and structure

Dosage form – drops eye 0,5% and 1%: transparent colourless solution (on 15 ml in ^{"Droptainer™"} bottles droppers from polyethylene of low density, 1 bottle in a pack cardboard).

Active agent: тропикамид, 1 ml of its solution contains 0,005 or 0,01 g.

Excipients: a benzalkoniya chloride, hydrochloric concentrated acid and/or sodium hydroxide, dinatrium эдетат, sodium chloride, the water purified.

Indications to use

Complex therapy of inflammatory diseases of eyes;
Prevention of development of synechias in the postoperative period;
Mydriasis before surgical (extraction of a cataract, operation on a vitreous and a retina) and laser (a lazerkoagulyatsiy retina) operations;
Mydriasis when carrying out a diagnostic oftalmoskopiya and determining a refraction.

Contraindications

Absolute:

Glaucoma, especially closed-angle and mixed primary;
Children's age up to 6 years (for solution of 1%);
Hypersensitivity to drug components.

Relative:

Inflammatory ophthalmologic diseases;
The increased intraocular pressure;
Superficial anterior chamber of an eye;
Prostatitis.

There are no data on safety of use of Midriatsil during pregnancy and a lactation therefore drug can be used only to destination the attending physician if the expected effect surpasses possible risks.

Route of administration and dosage

Midriatsil is applied locally.

For a diagnostic mydriasis dig in 1-2 drops of 0,5% of solution in 15-20 minutes prior to survey. At strong pigmentation of irises of the eye the dose can be increased.

For definition of a refraction 1-2 drops of 1% of solution dig in 2 times with a 5-minute interval. It is possible to make one more instillation for prolongation of effect.

Side effects

Local: short-term burning after an instillation, decrease in visual acuity, photophobia, increase in intraocular pressure, accommodation disturbance, a hyperemia and a chemosis, allergic reactions;
System (is more often at children and elderly people): dryness in a mouth, tachycardia, arrhythmias, tachycardia, a xeroderma, вертиго, a headache, decrease in a tone and motility of digestive tract (leads to a lock), a dysuria, psychotic reactions, rash, abdominal distention, hallucinations, lacks of coordination, fervescence, change of behavior, convulsion, a cardiopulmonary collapse.

Special instructions

Midriatsil is not intended for injection introduction.

For prevention of system absorption of a tropikamid and reduction of risk of development of system effects squeezing of a dacryocyst at an internal corner of an eye after instillation of drug within 1-2 minutes is recommended.

The patients carrying contact lenses should remove them before an instillation and to dress not earlier than in 15 minutes.

Owing to change of width of a pupil and accommodation Midriatsil can reduce visual acuity therefore during use of drug it is necessary to refrain from control of motor transport and the performance of work demanding the clearness of visual perception.

Medicinal interaction

Antihistamines derivative fenotiazina, quinidine, alpha and beta-adrenergic agonists: the risk of system reactions of a tropikamid increases;
Nitrates, glucocorticoids: there is a dangerous increase in intraocular pressure;
Antidepressants: mutual potentiation of effect of drugs is noted;
M-holinoblokatory: their effects amplify;
M-cholinomimetics: action of a tropikamid is weakened.

Terms and storage conditions

To store in the place, unavailable to children, at a temperature from 8 to 30 ºС.

Period of validity – 3 years. After the first opening of a bottle it is possible to store drops within 4 weeks.

Whether you know that:

In our intestines are born, millions of bacteria live and die. They can be seen only at strong increase, but if they gathered, then would be located in a usual coffee cup.

Тромбоз глубоких вен: 8 симптомов, сигнализирующих об опасности

Deep vein thrombosis: 8 symptoms signaling about danger

The varicosity has familiarly many, statistically, this disease more than a half of all adult population. As...