Оспамокс

Оспамокс – the antibiotic relating to penicillinic group.

Ospamoks's list and form of release

Оспамокс release in shape:

• Tablets, the film coated, containing 500 or 1000 mg of active ingredient – trihydrate amoxicillin, and also auxiliary components: sucrose, sodium saccharin, Natrium benzoicum. On 12 pieces in packaging;
• Granules for preparation of peroral suspension. In 5 ml of granules the operating components – amoxicillin trihydrate 125 or 250 mg and Natrium benzoicum of 25 mg, and also auxiliary components contain: sucrose, sodium saccharin, Natrium benzoicum. In bottles on 60 ml of suspension.

Pharmacological action

Оспамокс is the antibiotic relating to penicillinic group, possessing a wide range of antimicrobic action.

Ospamoks's use is efficient concerning the microorganisms sensitive to penicillin G, including stafilokokk which are not producing a penicillinase, streptococci of the group A, B, C, G, H, L and M, Streptobacilli spp., Streptococcus pneumoniae, Neisseria spp., Actinomycetes spp., Erysipelothrix rhysiopathiae, Pastereulla multocida, Spirochaeta, Listeria spp., Corynebacterium spp., Spirillium minus, Bacillus anthracis.

Also apply Ospamoks to gram-negative microorganisms: Leptospira, Chlamydia, Bordetella pertussis, Campilobacter spp., Haemophilus influenzae, Salmonella spp., Escherichia coli, Shigella spp., Proteus mirabilis; concerning anaerobic microorganisms, including Fusobacter spp., Peptococcus spp., Clostridium spp.

Indications to Ospamoks's use

According to the instruction of Ospamoks appoint for treatment of the diseases of infectious and inflammatory character caused by microorganisms, sensitive to amoxicillin, namely:

• bacterial meningitis;
• infections of lower parts of respiratory tracts (a chronic and acute bronchitis, abscesses of lungs, whooping cough in an initial stage and in the period of an incubation, pneumonia);
• infections of ENT organs and upper respiratory tracts;
• gynecologic infections (endometritis, adnexitis, septic abortion);
• digestive tract infections (paratyphoid, typhoid);
• infections of urinogenital bodies (gonorrhea, an urethritis, an epididymite, an asymptomatic bacteriuria during pregnancy, cystitis, prostatitis, a pyelitis, chronic pyelonephritis);
• hay fever;
• infectious endocarditis, including enterokokkovy;
• infections of bilious ways (cholecystitis, cholangitis);
• carriage of a salmonella;
• infections of skin and soft tissues;
• acute and latent listeriosis;
• septicaemia.

Also according to the instruction of Ospamoks appoint in the preventive purposes to patients during the postoperative period (for example, at operations in an oral cavity).

Route of administration of Ospamoks and mode of dosing

Ospamoks's dosage according to the instruction depends on localization and sensitivity of an infection. The daily dose is divided into several receptions.

Treatment duration: before disappearance of symptoms plus 2-5 days.

For suspension preparation the bottle with granules is filled with drinking water, stirred up, and then added by water to a ring tag. Before the use the bottle with ready suspension needs to be stirred up well.

Dosages of tablets and suspension are presented in the instruction to Ospamoks:

• children up to one year of life – suspension of 125 mg / 5 ml – 5 ml (1 spoon) twice a day;
• children from one to six years – suspension of 250 mg / 5 ml – 5-7,5 ml (1-1,5 spoons) twice a day;
• children from six to ten years – suspension of 250 mg / 5 ml – 7,5-10 ml (1,5-2 spoons) twice a day;
• children from ten to fourteen years – 1 tablet of 500 mg twice a day;
• teenagers – 1,5 tablets of 500 mg twice a day;
• adults – 1 tablet of 1000 mg twice a day.

Contraindications to Ospamoks's use

According to the instruction of Ospamoks it is contraindicated at:

• lymphoid leukosis;
• the heavy infections of digestive tract which are followed by vomiting or diarrhea;
• to hay fever;
• infectious mononucleosis;
• allergic diathesis;
• respiratory viral infections;
• to bronchial asthma;
• hypersensitivity to antibiotics of a penicillinic row.

Side effects of Ospamoks

According to Ospamoks causes the following by-effects:

• Central nervous system: increased fatigue, headache.
• Alimentary system: glossitis, nausea, stomatitis, diarrhea. The single reviews of Ospamoksa testimonial of insignificant increase in aminotransferases in blood serum arrived.
• Urinary system: seldom there is intersticial nephrite.
• System of a hemopoiesis: eosinophilia, agranulocytosis, thrombocytopenia.
• Leukopenia.
• Allergic reactions: seldom there is a joint pain, a small tortoiseshell, a Quincke's edema, fever. In isolated cases – exfoliative dermatitis, a mnogoformny erythema, an acute anaphylaxis. Reviews of Ospamoksa from the patients treating syphilis, leptospirosis or a typhoid about development of the reaction of Yarisha-Gerkskheymer caused by a lysis of bacteria arrived.

Special instructions

It is necessary to consider probability of development of a cross allergy in the patients having hypersensitivity to cephalosporins.

During Ospamoks's use an important role is played by maintenance of a sufficient diuresis and adequate consumption of liquid. To patients with cholecystitis or a cholangitis antibiotics are appointed only at easy forms of a disease.

At long therapy of Ospamoks according to reviews can cause the excess growth of resistant mushrooms and microorganisms.

Оспамокс according to the instruction do not appoint or appoint with care a sick diabetes mellitus as at its structure there is a sugar.

Reviews of Ospamoksa from patients with meningitis and epilepsy about developing of spasms arrived.

Periods of storage

At observance of conditions of a tablet of Ospamoks it is necessary to store not longer than four years, and a granule – not longer than three years.