Protopeak

The protopeak belongs to group of drugs which remove inflammations on integuments.

Release form, structure, packaging

Is issued in the form of homogeneous ointment of 0,03%. It is appointed only for external use. Has white, white-yellow tsvet.100 Protopika contains ointments 30 mg of a takrolimus.

In the instruction to Protopik it is specified that liquid paraffin (11 mg), white beeswax (3,5 mg), white soft paraffin (77,47 mg), propilencarbonate (5 mg), hard paraffin (3 mg) belongs to his additional components.

Besides, Protopik is made in the form of homogeneous ointment 0,1%. Has white, white-yellow color. 100 g of a product contain 100 mg of a takrolimus.

Liquid paraffin (11 mg), white beeswax (3,5 mg), white soft paraffin (77,47 mg), propilencarbonate (5 mg), hard paraffin (3 mg) belongs to additional substances.

Is on sale in plastic tubas of 10 g, 30 g and 60 g.

Pharmacological action of Protopik

In the instruction to Protopik it is noted that this medicine belongs to antiinflammatory drugs which are used only for outside use. Advantage of this drug is that its main component does not exert impact on synthesis of collagen and does not cause an atrophy of integuments.

Indications to Protopik's use

Most often Protopik and Protopik's analogs appoint to those patients at whom atopic dermatitis (a severe and average form) is observed. It becomes also in those cases if other drugs do not help patients or not side reactions on Protopik's components. To children at the age of 2-16 years appoint only 0,03% Protopik. To adults and children 16 years are more senior it is possible to use ointment of 0,1% and 0,03%.

Contraindications

Ointment Protopik is contraindicated:

• At a lamellar ichthyosis.
• In responses to Protopik it is told that ointment is forbidden to be used at pregnancy and in the period of a lactation.
• It is impossible to apply in the presence at a sick syndrome of Neterton or other genetic diseases of skin.
• If skin badly reacts to ointment.
• It is forbidden to put to children at the age of 2-16 years 0,1% ointment Protopik.
• It is strictly forbidden to put to children up to 2 years.
• If at patients hypersensitivity to the main thing and auxiliary components of drug is noted.

Patients with a liver failure, very big defeats of integuments, children, and also those patients who quite long time use this drug need additional consultation.

Route of administration of Protopik and mode of dosing

In the instruction to Protopik it is told that this ointment is applied to adults and children by a thin layer on affected areas of integuments (including a neck, a face, skin folds). It is necessary to avoid hit of ointment on mucous membranes, and also under the occlusive dressings used on various parts of a body.

Children aged from 2 up to 16 years have to begin treatment with Protopik's use of 0,03% to 2 times a day. The general course of treatment makes at most 3 weeks. After that ointment is applied before full clarification of skin once a day.

To adults and children 16 years a course of treatment are more senior begin with drawing 0,1% of means to 2 times a day. In case of bystry improvement, it is possible to use 0,03% drug or to reduce a dosage.

People of old age concerning Protopik's dosage do not need additional consultation.

Usually improvements at patients are noticeable after 7 days of therapy. If there is no improvement after 14 days of use of drug, then it is necessary to consult with the specialist.

Overdose

In responses to Protopik it is recorded that today cases of overdose were not observed.

At drug hit inside it is not necessary to cause vomiting or to wash out a stomach. It is necessary to ask for the help the doctor who will carry out control of the general condition of an organism.

Interaction with other medicines

In the instruction to Protopik it is specified that drug is not metabolized in skin.

Simultaneous drawing Protopik with such drugs as кетоконазол, erythromycin, diltiazem, итраконазол if the patient has a serious illness of extensive sites of integuments or the erythrosis is recorded is not excluded.

So far medical researches which would confirm influence of ointment on vaccination process were not conducted. However, despite it, at Protopik's use vaccination can become less effective. To avoid similar results, she will be seen to use of ointment or in 2 weeks after its use. If to the patient enter a live attenuirovanny vaccine, then this process has to begin 28 days later after the last day Protopik's uses. If this interval does not manage to be sustained, it is necessary to apply other vaccine.

Numerous experiments confirm that children from 2 to 11 years can apply on skin Protopik and at the same time to enter the conjugated vaccine.

Reaction of a human body to simultaneous use of Protopik with other ointments intended for external use and also immunodepressants is not known.

Side effects of Protopik

In responses to Protopik it is noted that most often after use of this means can arise burning sensation of integuments, an itch, reddening, rash and pain, and also hypostases in a specific site of application of drug. They pass within the first week of treatment and have poorly expressed character.

In responses to Protopik it is told that during the putting ointment and simultaneous alcohol intake in the increased quantities it is possible to provoke irritation of skin to skin.

Using ointment it is possible to provoke developing of an acne (meets extremely seldom), a folliculitis and a herpes infection. As for a nervous system, quite often there is a hyperesthesia and paresthesia.

During all the time after Protopik's appearance and Protopik's analogs in medical practice only several cases when at patients the carcinoma cutaneum, a rozatsea and other infections of integuments developed were noted.

Conditions and Protopik periods of storage

Drug and Protopik's analogs need to be stored far away from children in the place protected from light at a temperature which will not exceed 25 degrees. Not to use after a period of validity (3 years).

Special instructions

Patients who accept immunodepressants, and also to those which suffer from the inborn or acquired immunodeficiency cannot use protopeak.

When using Protopik's and Protopik's analogs it is impossible to visit sunbeds. It is necessary to avoid hit on a body of sunshine, and also it is impossible to carry out procedures with UV rays.

The protopeak is strictly forbidden to be applied on sites of skin which defeats are defined as malignant. Within 2 hours after Protopik's drawing on these sites of skin it is impossible to apply the softening ointments and creams. After ointment use surely it is necessary to wash up hands.