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Alexander disease

Alexander disease:

  1. (The modern American doctor V. of Alexander) – a hypoproconvertinemia: the heredo-familial disease caused by deficit of proconvertin (blood-coagulation factors of VII) – hemorrhagic diathesis; inheritance on autosomal recessively type;
  2. (Modern English neuropathologist of W. S. Alexander; synonym: Rosenthal a leukodystrophy) – the hereditary disease of the central nervous system which is characterized by disintegration of a myelin. Clinically the disease is shown by spasms, the progressing hydrocephaly and the central paralyzes.
 
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