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Antagonism of I (antagonism of substances)

Antagonism of I (antagonism of substances) (Greek antagonisma – rivalry, fight) – the type of interaction in an organism of substances (vitamins, amino acids, medicinal substances) which is characterized by the fact that because of one of them action of another is weakened.

Allocate the following types of antagonism of substances:

  • Absolute – effect of simultaneous effect of substances is less, than effect of each of them separately;
  • Bilateral – any of two substances removes or weakens action of another;
  • Competitive – substances interact with the same receptors of cells (has reversible character);
  • Non-competitive – direct antagonism, is characterized by the fact that one of the interacting substances affects a receptor out of its active center;
  • Indirect (synonym: antagonism indirect) – effect of substances is directed to various elements of cells;
  • Nonequilibrium – one of substances is irreversible interacts with receptors;
  • Unilateral – effect of one substance removes action of another, but not on the contrary;
  • Relative – effect of simultaneous effect of substances is more, than separate effects of each of them, but there is less summing of effects of the same substances operating separately;
  • Straight line – effect of substances is directed to the same cellular elements.
 
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