B13 vitamin (orotovy acid) was discovered at the beginning of the 20th century, namely, in 1904. Researchers revealed that it contains in milk of the person and animals. From the point of view of biochemistry B13 vitamin is rather vitaminopodobny substance as it not only comes to a human body together with food, but also is synthesized under influence of the beneficial bacteria which are in intestines.
Purely orotovy acid looks as crystal substance without color. In a human body it is designed to carry out a number of important physiological processes.
On average, the daily need for B13 vitamin of the adult makes 500-1500 mg. Pregnant women women and nursing mothers need twice more orotovy acid in days. Also athletes as it positively affects preservation and growth of muscle bulk need bigger amount of B13 vitamin.
B13 vitamin is present practically at all fabrics and members of the body and takes part in a number of the vital biochemical processes.
Orotovy acid helps production of special substances – phospholipids which are extremely necessary for creation and full work of cellular membranes. B13 vitamin by means of participation in biosynthesis of nucleic acids provides favorable conditions for separate cells and an organism in general. The positive impact of orotovy acid on processes of a krovoobrazovaniye is proved, in particular, B13 vitamin is capable to strengthen synthesis of blood cells (leukocytes and erythrocytes). This property allows to use it at treatment of the anemia caused by influence of the ionizing radiation when processes of a krovoobrazovaniye are broken.
It should be noted anabolic effect of orotovy acid, i.e. its ability to strengthen the speed of development of proteinaceous molecules, stimulating rapid growth of muscle bulk. Here pertinently will be to remember that many athletes accept drugs for the intensive growth of muscles as a part of which there are substances having anabolic effect. And, though, orotovy acid is not hormone, and represents connection of the nonsteroid nature, nevertheless, it also significantly stimulates growth of muscle fibers. Quite often it is appointed after long starvation and at decrease in body weight for the purpose of the fastest recovery of biosynthesis of protein in an organism.
Favorably B13 vitamin influences pregnancy development, promotes the correct fetation. Also orotovy acid improves work of a liver, promotes recovery of its cells that protects this vital from regeneration. B13 vitamin promotes decrease in level of cholesterol in blood therefore is quite good prevention of development of the atherosclerotic plaques narrowing a gleam of blood vessels and breaking work of cardiovascular system.
Medicines as a part of which there is a B13 vitamin are appointed to patients during the postoperative period and for recovery after a serious illness. Also orotovy acid is appointed for recovery of work of biliary tract and reduction of work of a cardiac muscle.
B13 vitamin in products contains in a type of potassium, magnesian and calcic salt. These connections, coming to a human body together with food, are soaked up in blood from intestines. In blood from these salts orotovy acid which spreads afterwards on fabrics and bodies of a human body is released.
The most widespread products with B13 vitamin are a yeast, liver and milk, and also various dairy products (kefir, cottage cheese, curdled milk, cheese). Quite often requirement of this vitamin is satisfied due to development with its microorganisms living in intestines.
Today pharmaceutical industry produces B13 vitamin in a dosage form in the form of salts – an orotat of magnesium or an orotat of potassium. But it is necessary to remember that first of all these drugs are medicinal, and it is not recommended to apply them without appointment of the doctor as additive to food. Uncontrolled reception of the medicines containing B13 vitamin in the structure can lead to undesirable effects and deterioration in health of the person. If you consider that reception of these drugs is necessary, previously consult with the doctor on existence of contraindications and definition of an optimum dosage.
At a lack of B13 vitamin of an organism there are irreversible disturbances of biochemical reactions. First of all, there is a deterioration in a current of skin diseases. However development of any specific states caused by a lack of B13 vitamin, medicine is unknown now.
It is necessary to consider that at a lack of B13 vitamin other vitamins of group B can partially fill shortage, to some extent providing reorganization of exchange processes.
As a rule, excess of B13 vitamin in a human body is observed at uncontrolled reception of medicines as a part of which there is orotovy acid. Excess of B13 vitamin can cause development of allergic reactions (an itch, reddening of integuments), and also digestive disturbances. After the termination of administration of drugs with the content of orotovy acid above-mentioned symptoms, as a rule, completely disappear.
Orotovy acid badly a rastvorima in organic solvents and water. B13 vitamin collapses under the influence of light.
It is established that digestion of B9 vitamin happens most effectively at enough orotovy acid in an organism. Besides, orotovy acid is capable to fill somewhat shortage in an organism of B12 vitamin (cyanocobalamine), providing thereby, full performance of some fermental reactions.
Sometimes doctors appoint B13 vitamin reception for improvement of portability of some antibiotics.
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