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Alpha нормикс – the antibiotic of a broad spectrum of activity belonging to group of Rifamycinum.
Active agent – рифаксимин with polymorphic structure an alpha:
Additional components of tablets:
Auxiliary components of granules: karmelloza of sodium, sucrose, kaolin, pectin, cellulose microcrystallic, Natrium benzoicum, sodium saccharinate, fragrance cherry (wild sweet cherry).
Alpha нормикс – drug for treatment of the gastrointestinal infections caused by microorganisms, sensitive to a rifaksimin, including:
Also the Alpha нормикс is applied to prevention of infectious complications when carrying out colorectal surgical interventions.
Alpha нормикс it is necessary to accept inside, washing down with a large amount of water (200 ml). Meal does not influence efficiency of drug.
From granules prepare suspension. For this purpose to a mark add water to a bottle and well stir up. If necessary add a little more water until the level of suspension reaches a point of 60 mg. Before reception drug should be shaken up well. For convenience of dosing the measured cup is provided in a set.
The recommended dosages depending on indications:
In some cases the doctor can change a dose and/or frequency of reception.
At diarrhea of travelers duration of treatment should not exceed 3 days, in other cases – 7 days. If necessary with an interval of 20-40 days carry out a repeated course of treatment.
For prevention of post-operational complications at colorectal surgical interventions appoint 2 tablets or 20 ml of suspension each 12 hours in 3 days prior to operation.
According to clinical data, the Alpha нормикс it is inefficient at the intestinal infections caused by Shigella spp, Salmonella spp., Campylobacter jejuni which cause fever, diarrhea and release of blood with a chair.
If within 48 hours symptoms of diarrhea amplify or remain, it is necessary to cancel the Alpha нормикс and to appoint other antibacterial therapy. The same concerns cases of development of the superinfection caused by microorganisms, insensitive to a rifaksimin.
As well as at use practically of all other antibacterial agents, during treatment the Alpha normiksy development of the diarrhea associated with Clostridium difficile is possible. It is impossible to exclude potential probability of development of pseudomembranous colitis.
Rifaksimin can paint urine in red color.
Owing to influence on an indestinal flora рифаксимин can reduce efficiency of the oral contraceptives containing estrogen (especially in concentration less than 50 mkg) therefore during treatment it is recommended to use additional measures of contraception.
At the combined use with absorbent carbon the Alpha нормикс it is necessary to accept not earlier than in 2 hours after it.
Drug in certain cases can cause drowsiness and dizziness. Such patients should refrain from driving and performance of potentially dangerous types of works.
At patients with abnormal liver functions рифаксимин, presumably, can reduce exposure of medicines of CYP3A4 substrates, for example, of anticonvulsant and antiarrhythmic drugs, warfarin.
To store at a temperature up to 30 ºС in the place, unavailable to children.
Period of validity – 3 years.
The suspension prepared from granules can be stored within 7 days at the room temperature (to 30 ºС).
Name of drug
Alpha Normiks of a tablet 200 of mg of 12 pieces
Alpha нормикс тбл п/пл/о 200 mg No. 12, Alfa-Wassermann
Alpha Normiks of a tablet of 200 mg 28 pieces
Alpha нормикс тбл п/пл/о 200 mg No. 36, Alfa-Wassermann
Alpha Normiks of a tablet 200 of mg of 36 pieces
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