Anaprilin
Application instruction:
Anaprilin – the drug of a synthetic origin relating to group of β-adrenoblockers and applied at treatment of supertension and disturbances of cardiac performance.
Form of release and structure
- Tablets: on 10 and 40 mg (in blister strip packagings on 10 or 20 pieces, in a cardboard pack of 5 or 10 packagings; on 100 pieces in banks of dark glass, in a cardboard box of 1 bank);
- Solution for intravenous administration (in ampoules on 1 ml and 5 ml).
Active ingredient of tablets and solution for in/in – propranolol.
Auxiliary components of tablets: potato starch, sugar milk, calcium stearate, talc.
Indications to use
Anaprilin appoint according to the following indications:
- Stenocardia;
- Various disturbances of a heart rhythm connected with damages of heart of rheumatic character (arrhythmia, Bouveret's and sinus disease, premature ventricular contraction, a ciliary tachyarrhythmia);
- Idiopathic hypertensia;
- Pheochromocytoma (Anaprilin apply with alpha adrenoblockers);
- Intoxication foxglove drugs;
- Thyrotoxicosis;
- Coronary heart disease.
Anaprilin also strengthens reductions of a uterus, reduces bleedings at childbirth and during the postoperative period.
Contraindications
- Myocardial infarction in an acute stage;
- Diabetes mellitus with ketoacidosis;
- Disturbances of a peripheral arterial blood-groove;
- Spastic colitis;
- Sinus bradycardia;
- Hay fever;
- Total and incomplete atrioventricular block (with left-and right ventricular heart failure).
Anaprilin's use along with hypoglycemic means is appointed only under strict control of the doctor (in order to avoid development of a hypoglycemia).
Route of administration and dosage
Doses of drug are appointed by the doctor.
In the form of tablets drug is used in 10-30 minutes prior to food. Tablets should be washed down with a large amount of water. An initial dose of means – 10 mg, at good tolerance increase in the specified dose on 20 mg a day is possible. It is possible to lift a daily dose to 80-100 mg (in 4 receptions), at a subtle effect – to 160-180 mg of 4-6 times a day.
At intake Anaprilin is quickly soaked up and brought from an organism. Semi-removal of drug takes place in 3-5 hours, and at prolonged use – 12 hours (90% of means are removed by kidneys as metabolites, in an invariable look there is about 1%).
Side effects
Anaprilin's use can cause the following side effects: vomiting, nausea, diarrhea, deterioration in a dream, dizziness, the general weakness, hypotonia, Reynaud's syndrome, an itch of integuments, bradycardia, symptoms of insufficient blood circulation, impotence (at prolonged use), a bronchospasm.
Special instructions
Anaprilin's use has to be appointed with care at the following diseases / states:
- Predisposition to a bronchospasm;
- Pregnancy and lactation;
- Children's and advanced age;
- Renal and liver failure;
- Diabetes mellitus;
- Bronchial asthma;
- Depression;
- Occlusal diseases of peripheral vessels.
Analogs
Analogs of drug are Vero-Anaprilin, Inderal, Obsidanum, Propranolol and Propranobene.
Terms and storage conditions
It is necessary to store Anaprilin at a temperature of 8-25 °C in the dry and dark place unavailable to children.
Period of validity – 4 years.
Name of drug
Price
Drugstore
Anaprilin тбл 10 mg No. 56 *, Updating of CJSC PFK
22 rub.
Network of the Moscow drugstores of IFCAnaprilin тбл 40 mg No. 56 *, Updating of CJSC PFK
38 rub.
Network of the Moscow drugstores of IFCAnaprilin тбл 10 mg No. 112 *, Updating of CJSC PFK
42 rub.
Network of the Moscow drugstores of IFCThe weight of a human brain makes about 2% of all body weight, however it consumes about 20% of the oxygen coming to blood. This fact does a human brain extremely susceptible to the damages caused by shortage of oxygen.
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