Benzonal
Application instruction:
Benzonal – synthetic drug with anticonvulsant action.
Form of release and structure
Benzonal is produced in the form of tablets (on 10 pieces in blister strip packagings, on 3 or 5 packagings in a cardboard pack; on 50 pieces in bottles).
Active ingredient: petrolbarbital, in 1 tablet – 0,05 g (tablets for children) or 1 g.
Indications to use
- Epilepsy of various genesis;
- Generalized and partial attacks;
- Epileptic syndrome.
Contraindications
- Hypersensitivity to the components which are a part of tablets;
- Chronic heart failure of the II-III Art.;
- Liver failure (including chronic);
- Adrenal insufficiency;
- Bronchial asthma;
- Thyrotoxicosis;
- Hyperkinesia;
- Anemia;
- Porphyria;
- Diabetes mellitus;
- Respiratory insufficiency;
- Depressions (with suicide attempts).
Route of administration and dosage
It is necessary to accept the tablets Benzonal 3 times a day (after food).
The one-time dosage for adults makes 0,1 g, maximum one-time – 0,3 g. In days it is impossible to accept more than 0,8 g of drug.
To children usually appoint (a one-time dose / a daily dose):
- 3-6 years – on 0,025-0,05 g / 0,1-0,15;
- 7-10 years – on 0,05-0,1 g / 0,15-0,3;
- 11-14 years – on 0,1 g / 0,3-0,4;
- 14 years – on 0,15 g / 0,45 are more senior.
As a rule, for achievement of therapeutic effect it is necessary to carry out prolonged continuous treatment which duration is defined by the doctor.
Side effects
At use of Benzonal can arise:
- Medicinal dependence, accustoming, withdrawal;
- Drowsiness, slackness, block;
- Headache;
- Bronchospasm;
- Lowering of arterial pressure;
- Nystagmus;
- Loss of appetite;
- Anemia;
- Thrombocytopenia;
- Thrombophlebitis;
- Delay of mental reactions;
- Difficulty of the speech, ataxy;
- Allergic reactions.
Special instructions
It is necessary to consider that Benzonal:
- Strengthens effect of narcotic analgetics, medicines for the general anesthesia, hypnotic drugs and antipsychotic drugs (neuroleptics), anxiolytics, ethanol, tricyclic antidepressants;
- Reduces effect of tetracyclines, anticoagulants, vitamin D, paracetamol, griseofulvin, glucocorticosteroids, quinidine, cardiac glycosides, xanthines.
If prior to therapy of the patient accepted other barbiturates, the sleep disorder can be observed. In this case usually appoint 50-100 mg of phenobarbital or other somnolent medicines.
Now at treatment of epilepsy Benzonal is appointed usually in cases when other antiepileptic medicines (carbamazepine, valproic acid) are inefficient.
Analogs
On the action mechanism analogs of Benzonal are: Hexamidine, Primidonum, Phenobarbital.
Terms and storage conditions
Drug is released according to the recipe of the doctor. A period of validity – 4 years at a temperature up to 25 °C.
The well-known drug "Viagra" was initially developed for treatment of an arterial hypertension.
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