Tserepro

Tserepro treats nootropic drugs, cholinomimetics of the central action. The operating component – sincaline альфосцерат. As a part of Tserepro 40,5% of sincaline contain in metabolic protected look (metabolic protection provides release of sincaline in a brain). In an organism under the influence of fermental systems drug is split on glycerophosphate and sincaline. Sincaline takes part in processes of biosynthesis of acetylcholine (one of the most important mediators of nervous excitement). Glycerophosphate – the predecessor of phospholipids of a neural membrane (phosphatidylsincaline).

Tserepro provides sufficient synthesis of phosphatidylsincaline and acetylcholine in neural membranes, improvement of a blood-groove and strengthening of the metabolic processes proceeding in TsNS. Also drug activates a reticular formation, provides improvement of linear speed of a blood-groove in the field of traumatic damage of a brain, normalizes spatio-temporal characteristics of bioelectric spontaneous activity of a brain, positively influences behavioural and cognitive reactions at patients with vascular pathology of a brain.

At Tserepro's use functions of a brain by impact on pathogenetic links of an involutional psychoorganic syndrome improve, the phospholipidic structure of neural membranes changes, cholinergic activity decreases. Drug дозозависимо strengthens allocation of acetylcholine, taking part in phosphatidylsincaline synthesis, improves plasticity of neural membranes, synoptic transfer, function of receptors.

Thanks to high neurophysiological activity of this drug reviews of Tserepro from neurologists positive. Experience of use of Tserepro testifies to its efficiency at organic pathology of TsNS.

Absorption of drug after oral administration makes 88%. Tserepro gets through a blood-brain barrier, concentration of drug in a brain makes about 45% of plasma concentration. Drug is removed by lungs (85%), and also with urine and a stake (15%).

Indications to Tserepro's use

According to the instruction to Tserepro, this drug is used at:

• acute and recovery period of heavy ChMT, ischemic stroke;
• recovery period of a hemorrhagic stroke;
• psychoorganic syndrome against the background of involutional and degenerative changes of a brain;
• chronic insufficiency of cerebral circulation;
• cognitive frustration (disturbance of memory, cogitative function, confusion of consciousness, disorientation, decrease in initiative, motivation, concentration of attention);
• senile pseudo-melancholy.

Contraindications to Tserepro's use

According to the instruction to Tserepro, contraindications to its use are:

• hypersensitivity to components;
• pregnancy, lactation.

Side effects

Side effects at Tserepro's use arise quite seldom. Emergence of nausea (owing to dopaminergic activation), and also allergic reactions is registered.

Route of administration of Tserepro and dosage

At acute conditions of Tserepro enter intravenously slowly or intramusculary. The daily dosage makes 1 g (this dose contains in 1 ampoule). Duration of parenteral treatment – 10-15 days. Further transition to oral administration of drug on 1,2g in days (2 capsules in the morning and 1 capsule in the afternoon) for half a year is recommended.

At chronic pathology of Tserepro it is appointed inside in a dosage of 400 mg three times a day. Capsules are recommended to be accepted before food.

Duration of treatment of Tserepro and analogs in a specific clinical case is determined by the doctor.

Overdose

At Tserepro's overdose there are dyspepsia phenomena. Therapy is nonspecific: carry out a gastric lavage, symptomatic therapy, enterosorbents are appointed.

Tserepro's use at pregnancy and a lactation

Tserepro's drug is contraindicated during pregnancy, a lactation.

Special instructions

In case of developing of nausea after Tserepro's reception it is recommended to lower a drug dosage.

Responses

This drug has high performance at the pathology of a brain proved in clinical trials; it is safe, at use in the recommended dosages extremely seldom causes side effects therefore reviews of Tserepro from doctors and patients positive.

Tserepro's analogs

The following analogs of Tserepro are registered: Gliatilin, Gliatser, Glitserilfosforilkholin hydrate, Nookholin Romfarm, Deletsit, Fosal, Holina альфосцерат hydrate, Tsereton, Holitilin.

This drug is used exclusively on doctor's orders.

Before administration of drug it is recommended to study the instruction to Tserepro.