Dazolik
Application instruction:
Dazolik – antiprotozoan medicine with antibacterial activity.
Form of release and structure
Dazolik release in the form of tablets, film coated: almost white or white color, biconvex, round, with risky on one of the parties; on a break – the kernel of almost white or white color surrounded with a cover (on 10 pieces in blisters, on 1 or 5 blisters in a cardboard pack).
Is a part of 1 tablet:
- Active agent: орнидазол – 500 mg;
- Auxiliary components: starch, the purified talc, microcrystallic cellulose, sodium carboxymethylstarch (type A), sodium lauryl sulfate, titanium dioxide, K90 povidone, magnesium stearate, colloid silicon dioxide, copolymer of butylmethacrylate, methylmethacrylate and dimethylaminoethylmethacrylate [1:1:2] (eudragit E100), a macrogoal 6000.
Indications to use
- Trichomoniasis;
- Lambliasis;
- Amoebic dysentery, amebiasis, abenteric amebiasis (including amoebic abscess of a liver);
- The infections caused by anaerobic bacteria (for prevention when carrying out operations in gynecology and on a colon).
Contraindications
- Age up to 3 years;
- Hypersensitivity to drug components.
Dazolik need to take with caution the feeding and pregnant women, and also at diseases of the central nervous system (including epilepsy, multiple sclerosis), alcoholism and diseases of a liver.
Route of administration and dosage
Pill should be taken inside after food.
The scheme of use of drug is defined by indications:
- Trichomoniasis: adult – once 1500 mg or 1000 mg in a combination with intravaginalny introduction of vaginal tablets on 500 mg for the night. It is possible to carry out therapy within 5 days, accepting drug in 2 times a day (in morning and evening) on 500 mg along with use for night of 1 vaginal tablet on 500 mg. To children Dazolik appoint once, establishing a dose at the rate of 25 mg/kg of body weight;
- Lambliasis: adults and children with body weight from 35 kg – on 1500 mg once a day, children of 3 years and with body weight to 35 kg – on 40 mg/kg a day. Therapy duration – 1-2 days;
- Amoebic dysentery: children with body weight from 35 kg and adults – once a day on 1500 mg, with body weight from 60 kg – on 2000 mg a day. To children of 3 years and with body weight to 35 kg the daily dose is defined at the rate of 40 mg/kg of body weight. Therapy duration – 3 days;
- Other forms of an amebiasis: children of 12 years and adults – on 500 mg 2 times a day; children of 3 years and with body weight to 35 kg – at the rate of 25 mg/kg of body weight, frequency rate of use – once a day. Therapy duration – 5-10 days.
For prevention of the infections caused by anaerobic bacteria Dazolik appoint 500-1000 mg before operation and 2 times a day on 500 mg within 3-5 days after operation.
Side effects
During therapy development of the following side effects is possible:
- Alimentary system: increase in activity of liver enzymes, nausea;
- Central and peripheral nervous system: the temporary loss of consciousness, a headache, drowsiness, a peripheral neuropathy (mixed or touch), a tremor, dizziness, muscle tension, spasms, an incoordination of movements, fatigue, a perversion of flavoring feelings;
- Others: allergic reactions.
Special instructions
At trichomoniasis both sexual partners need to carry out simultaneous therapy.
As орнидазол depressing influences the central nervous system, it should not be applied during control of motor transport or when working, the movements demanding accurate coordination.
Medicinal interaction
Unlike other imidazolny derivatives (metronidazole), Dazolik does not inhibit an atsetaldegiddegidrogenaza and therefore it is compatible to ethanol.
At simultaneous use орнидазол can strengthen effect of indirect anticoagulants of a coumarinic row and extend myorelaxation action a bromide vekuroniya.
Terms and storage conditions
To store at a temperature up to 25 °C in protected from light, the place, dry, unavailable to children.
Period of validity – 3 years.
Name of drug
Price
Drugstore
Dazolik тбл п / about 500 mg No. 10, Sun Pharmaceuticals
341 rub.
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