Fenotropil

Fenotropil – nootropic drug. Active ingredient - N-karbamoil-methyl-4-phenyl-2-пирролидон. Drug has ability in the direct way to improve integrative function of a brain. It leads to improvement of mental capacities, learnability, memory consolidation, improvement of attention. Besides, Fenotropil has anticonvulsant effect, anxiolytic properties, improves mood, normalizes processes of braking and excitement in a brain, possesses anorexigenic action. At course use Fenotropil increases stability of tissues of brain in the conditions of a hypoxia. Thanks to neurotyre-tread properties of Fenotropil of the indication to its appointment include also the pathology caused by influence of toxic substances, hypoxias. Drug improves blood supply of a brain, stimulates exchange processes in neurons.

Fenotropil has ability to raise a regional blood stream at a hypoxia. Improvement of energy potential of neurons is provided with the strengthened glucose utilization. Fenotropil does not influence CCC and a respiratory organs. It is noted that at course reception of Fenotropil visual acuity improves, perception of brightness of flowers amplifies.

Drug Fenotropil has adaptogenny properties (increases resistance to a stressful situation) that is especially shown at essential emotional and exercise stresses.

Fenotropil moderately influences motor reactions, reduces the inhibiting impact of ethanol and hexenal on brain tissues. Is an antagonist of cataleptic influence of neuroleptics.

Fenotropil has some analgesic effect thanks to increase in a threshold of painful sensitivity. Also this drug improves a blood stream in vessels of the lower extremities. Lack of teratogenic, cancerogenic, mutagen, embriotoksichesky influence and a hypotoxicity belongs to positive properties of Fenotropil.

At course reception of this drug the withdrawal phenomena were not noted that supports positive reviews about Fenotropile. Besides, tolerance and medicinal dependence to drug does not develop. Fenotropil – the patented drug. There are no Fenotropil's analogs yet.

At oral administration drug is quickly soaked up in a GIT, gets through a blood-brain barrier. The maximum concentration is reached in an hour after reception. It is not metabolized in an organism. An elimination half-life – 3-5 hours. 60% of drug are removed with then and bile, 40% – with urine. Fenotropil's bioavailability is characteristic 100%.

Indications to Fenotropil's use

In the instruction to Fenotropil such indications to appointment are specified:

• the neurotic states which are characterized by deterioration in a psychophysical activity, excessive fatigue, slackness, decrease in memory, disturbance of cognitive functions;
• depressions;
• TsNS pathology associated with disturbance of metabolism in a brain and blood supplies and also other diseases which are followed by disturbance intellectual мнестической functions;
• convulsive diseases;
• need of inverting of the mode of a dream wakefulness (in connection with professional activity);
• alimentary and constitutional obesity;
• schizophrenia (vyaloapatichesky current);
• with the preventive purpose at stressful situations, extreme influences of professional activity, at a hypoxia, for stimulation of intellectual and physical effeciency;
• alcoholism (for reduction of an adynamy, a depression, increase intellectual мнестических functions);
• psychoorganic syndrome with the phenomena of slackness, apathy, abulichesky frustration.

Contraindications to Fenotropil's use

According to the instruction to Fenotropil, a contraindication to use of this medicine – the increased individual sensitivity to the components which are a part of drug.

Route of administration, dosage

Fenotropil is intended for oral administration. The pill should be taken after food. The drug dosage, and also duration of therapy is defined by the doctor depending on a clinical situation. The average dosage of Fenotropil on one reception makes 100-250mg. The maximum daily dosage – 750 mg. The daily dosage is recommended to be divided into two receptions. If the daily dosage makes 100 mg, we will allow a single dose in days. The average duration of a course of treatment – month. At alimentary and constitutional obesity Fenotropil is applied on 100-200mg within one-two months.

It is desirable to accept Fenotropil no later than 15:00.

Side effect

Fenotropil has a number of side effects: at late reception of a tablet night sleeplessness is possible, emergence in the first three days of treatment of such phenomena as erubescence, psychomotive arousing, feeling of inflows of heat, arterial hypertension is also noted.

Fenotropil's use at pregnancy

Teratogenic and embriotoksichesky influence of drug is not revealed, however in view of insufficient clinical experience Fenotropil's use during pregnancy and a lactation is not recommended. Due to the same reason Fenotropil is not applied in pediatrics.

Fenotropil's interaction with other drugs

Fenotropil exponentiates effect of the anxiolytics and means exciting TsNS.

Responses

Thanks to high activity of drug reviews of Fenotropila positive both from patients, and from doctors. Patients note rather easy portability of Fenotropil. Indications to drug use quite extensive, and the set of pharmacological effects gives the chance to achieve desirable clinical result.

Fenotropil's analogs

There are no Fenotropil's analogs now.

Persons of the instruction

At a chronic stress, overfatigue, considerable psychoemotional exhaustion increase in need of an organism for a dream in the first days of reception of Fenotropil is possible. In such cases it is recommended to begin use of drug on the weekend. With care it is necessary to appoint Fenotropil at atherosclerosis, pathology of a liver, kidneys, existence of the panic attacks in the anamnesis, in the period of an acute psychotic state, and also in the presence in the anamnesis of an allergy to other nootropa.

Before use of this drug it is necessary to study the instruction to Fenotropil.

Use of this drug is possible exclusively on doctor's orders.