Flemoksin солютаб

Flemoksin солютаб is the antibiotic from group of semi-synthetic penicillin possessing a broad spectrum of activity. Active ingredient – amoxicillin trihydrate. Drug has bactericidal effect. Flemoksin солютаб has high activity concerning many microorganisms, in particular S.pneumoniae, Staphylococcus aureus, Moraxella catarralis, Streptococcus pyogenus, Staphylococcus spp, Neisseria gonorrhoeae, Clostridium tetani, N.meningitidis, Bacillus anthracis, Haemophilus influenzae, Listeria monocytogenes, Helicobacter pylori, and also a little smaller efficiency concerning causative agents of some intestinal infections: Escherichia coli, Enterococcus faecalis, Shigella sonnei, Proteus mirabilis, Salmonella typhi, Vibrio cholere. Flemoksin солютаб and analogs of drug are inactive concerning the bacteria capable to produce beta lactamazu.

Flemoksin солютаб has ability to be absorbed quickly in digestive tract at oral administration, the maximum concentration of active ingredient in plasma is reached in 1-2 hours. At reception of this form of drug higher concentration of amoxicillin in a blood plasma is reached, than when using an insoluble form.

Active ingredient of drug Flemoksin солютаб in number of 20% contacts plasma proteins. In a therapeutic dose drug collects in a bone tissue, a phlegm, intraocular liquid, mucous. Concentration of drug in bile is 2-4 times higher, than in blood. In meningeal liquid no more than 20% of the plasma contents of active ingredient concentrate.

Drug removal Flemoksin солютаб and analogs happens only kidneys. About 90% of amoxicillin are removed with urine in 8 hours after reception. At decrease in clearance of creatinine below 15ml/mines time of semi-removal of active ingredient considerably increases, up to 8,5 hours at an anury.

Drug can be used at children already from age of 1 year, and taking into account its high performance pediatricians give good comments on Flemoksin солютаб.

Indications to Flemoksin's use солютаб

Flemoksin солютаб is applied at the following diseases caused by microorganisms, sensitive to active ingredient:

• infections of respiratory system,
• gastrointestinal diseases,
• infections of an urinary system,
• infectious diseases of soft tissues and skin.

The instruction to use

According to the instruction Flemoksin солютаб it is possible to accept irrespective of the meal mode. It is possible either to swallow a tablet entirely, or previously having divided into parts. To wash down with a large amount of water. It is also possible to dissolve a tablet in 200 ml of water, at the same time suspension with citrus taste is formed.

At slight and medium-weight infectious diseases Flemoksin солютаб in the following doses is recommended to apply:

• for adults and children of 10 years: 500-750mg twice a day or 500 mg three times a day;
• for children of 3-10 years: 250 mg three times a day;
• for children of 1-3 years: 250 mg twice a day or 150 mg three times a day.

The average daily dose for children makes 30mg/kg.

At heavy infectious pathology, and also in case of chronic diseases and a recurrence the dose can be increased.

In each specific clinical situation Flemoksin солютаб and analogs defines a drug dosage the attending physician.

Duration of use of Flemoksin солютаб

According to the instruction Flemoksin солютаб at infections easy or moderate severity accept 5-7 days, in cases of the infections caused by a streptococcus - not less than 10 days.

At heavy infections and chronic pathology duration of reception of Flemoksin солютаб and analogs depends on disease.

Contraindications to Flemoksin's use солютаб

In the instruction to Flemoksin солютаб the following contraindications to its use are described:

• hypersensitivity to penicillin and cephalosporins,
• leukemoid tests of lymphatic type,
• infectious mononucleosis.

Side effects

At administration of drug emergence of certain side effects about which tell also comments on Flemoksin солютаб from patients is possible. These are such effects as:

• from gastrointestinal system: diarrhea, vomiting, nausea, an itch in the field of an anus, antibiotikoassotsiirovanny colitis,
• from skin: itch, urticaria,
• from kidneys: intersticial nephrite,
• very seldom there are heavy allergic reactions: Stephens's syndrome – Johnson, a multiformny erythema, a toxic epidermal necrolysis.

Special instructions

Patients with heavy allergic pathology in the anamnesis have a high risk of development of an anaphylaxis at administration of drug Flemoksin солютаб.

The patients suffering from an infectious mononucleosis at reception of this drug have a rash which is not connected with hypersensitivity to drug. Such episodes in the anamnesis are not a contraindication to Flemoksin's use солютаб.

At purpose of drug Flemoksin солютаб and analogs it is necessary to consider existence of cross hypersensitivity between cephalosporins and drugs of a penicillinic row.

At administration of drug in a high dosage it is necessary to pay attention to the use of a large amount of water for the purpose of prevention of a crystalluria.

Drug storage conditions

According to the instruction Flemoksin солютаб it is necessary to store at the room temperature in the place unavailable to children.

Flemoksin's use солютаб at pregnancy

Use of this drug during pregnancy is possible, however has to take place under strict control of the attending physician and only on his appointment.

Analogs

In drugstores the following analogs of Flemoksin солютаб meet: Amoksisar, Amoksitsillin, Amosis, Gonoform, Gramoks-D, Gryunamoks, Danemoks, Ospamoks, Hikontsil, Ekobol.

Reviews of drug

Thanks to high performance of drug, a broad spectrum of activity, a possibility of appointment in different clinical situations the practicing doctors give very good comments on Flemoksin солютаб. Efficiency of drug is proved in a number of clinical tests. Resistance of microorganisms to active ingredient low. Comments on Flemoksin солютаб from patients also speak about its efficiency, and the form of release is very convenient in use, including in pediatric practice.

Before use of drug it is necessary to study in detail the instruction to Flemoksin солютаб, to pay special attention to contraindications. Often negative comments on Flemoksin солютаб are connected with non-compliance with recommendations about its use therefore the risk emergence of side effects significantly increases.