Solution for intramuscular (in oil) and hypodermic (п / to) introductions: transparent colourless liquid (on 5 or 10 ampoules in a blister strip packaging, in a cardboard pack 1 or 2 packagings);
Suppositories for rectal use: a torpedo-shaped form with homogeneous structure from color, white to white with a yellowish shade, can have a slight specific smell (on 5 or 10 pieces in a blister strip packaging, in a cardboard pack 1 or 2 packagings);
Spray for nasal use dosed: colourless, transparent or poorly opalescent liquid, is allowed existence of a slight specific smell (on 8,5 ml in a plastic bottle with the portioning device, in a cardboard pack 1 bottle).

Active agent – имунофан:

1 ml of solution – 50 mkg;
1 suppository – 100 mkg;
1 dose of spray – 50 mkg.

Auxiliary components:

Solution: sodium chloride, glycine, water for injections;
Suppositories: glycine, the twin 80, solid fat, the water purified;
Spray: a benzalkoniya chloride, sodium эдетат (Trilonum of B), sodium chloride, glycine, the water purified.

Indications to use

Imunofan's use is shown for prevention and treatment of chronic inflammatory diseases of various etiology, immunodeficient and toxic states.

Besides, drug is appointed:

Solution for injections and suppositories rectal – at vaccination against viral and bacterial infections as adjuvant (only the adult);
Spray nasal – at therapy of acute forms of infectious and inflammatory pathologies.

Contraindications

Age up to 2 years;
Hypersensitivity to drug components.

In addition, solution and suppositories rectal it is contraindicated to apply to injections at the pregnancy complicated a Rhesus factor conflict.

With care it is recommended to apply spray nasal during pregnancy and breastfeeding.

Route of administration and dosage

Solution is intended for п / to or injections in oil, drug is appointed courses, a daily (one-time) dose – 50 mkg.

Suppositories apply rektalno in a daily (one-time) dose – 100 mkg.

Spray is used intranazalno, for this purpose it is necessary (at vertical position of a bottle and the patient's head) to insert the sprayer into the nasal course and to press against the stop a wide rim of the device. Use of a new bottle should be begun with filling of a dispensing pump, having pressed 3-4 times a wide rim of the device of spraying. One dose of spray contains 50 mkg of an imunofan. The maximum daily dose – 200 mkg.

Frequency rate of reception of Imunofan in the form of solution and suppositories – 1 time a day, spray – 1-2 times. The course of treatment depends on clinical testimonies and age of the patient:

Oncological pathologies in the scheme combined radical (operation, himioluchevy therapy) treatments: 8-10 injections or suppositories (on 1 dose of spray in each nasal course within 8-10 days) before operation and himioluchevy therapy, then with breaks on 15-20 days between courses throughout the entire period of therapy;
Widespread tumoral process (III-IV stage of an oncological disease) of various localization (complex or symptomatic therapy): 8-10 injections or suppositories (on 1 dose in each nasal course within 8-10 days), this course it is necessary to repeat after a break in 15-20 days throughout the entire period of therapy;
Malignant diseases of lymphoid and hemopoietic systems at children: 10-20 injections or suppositories throughout the entire period of himioluchevy therapy and after end for prevention of development of toxicosis;
Papillomatosis of a throat and stomatopharynx at children (as a part of complex therapy): 10 injections or suppositories;
Cytomegaloviral and herpes infection, cryptosporidiosis, toxoplasmosis, pneumocystosis, clamidiosis: 15-20 injections or suppositories, or on 1 dose of spray in each nasal course 2 times a day within 10-15 days, repetition of courses perhaps after a break in 2-4 weeks;
HIV infection (as a part of complex therapy): 15-20 injections or suppositories (on 1 dose in each nasal course for 10-15 days), carrying out repeated courses perhaps after a break in 2-4 weeks;
Chronic forms of a viral hepatitis and brucellosis: 15-20 injections or suppositories (on 1 dose in each nasal course within 10-15 days), for prevention of a recurrence in 2-3 months are recommended to carry out repeated courses of treatment (for spray nasal – in 4-6 months);
Diphtheria: 8-10 injections or suppositories, to carriers of bacteria of diphtheria – 1 time in 3 days, the treatment period – 3-5 injections or suppositories;
Psoriasis: 15-20 injections or suppositories;
Burns of the III-IV degree with signs of a toxaemia and a septicotoxemia, a septic endocarditis, it is purulent - septic complications after surgeries, is long not healing wounds of extremities: 7-10 injections or suppositories, in hard cases treatment it is recommended to continue up to 20 days;
Vaccinal prevention: only the adult – 1 injection (1 suppository) in day of vaccination.

At treatment of a bronkhoobstruktivny syndrome, pseudorheumatism, holetsistopankreatit Imunofan appoint 1 time in 3 days, the period of treatment consists of 8-10 suppositories or injections, in case of need the course should be prolonged according to the same scheme up to 20 procedures.

Use of spray at acute and chronic infectious and inflammatory diseases with symptoms of intoxication and an immunodeficiency is made as a part of complex therapy daily on 1 dose in each nasal course by 2 times a day, within 10-15 days.

Side effects

Development of side effects is possible at individual intolerance of drug.

Special instructions

Owing to activation of phagocytosis the short aggravation of the centers of a chronic inflammation supported thanks to preservation of functional activity of viral or bacterial antigens can be observed.