Main > Drugs> Espa-Lipon

Espa-Lipon

The prices in Internet drugstores:

from 718 rub.

Espa-Lipon – a gepatoprotektor, Капсулы Эспа-Липонthe drug increasing resistance of a liver to influence of adverse factors. Besides, Espa-Lipon's action extends to regulation of lipidic and carbohydrate metabolism in an organism.

Dosage forms of means – biconvex round tablets of yellow color, coated and transparent solution for injections of a chartreuse shade.

Espa-Liponav active ingredient tablets – thioctic acid (200 and 600 mg). Auxiliary components: povidone, monohydrate of lactose, microcrystallic cellulose, colloid silicon dioxide, sodium carboxymethylstarch, silicon dioxide, magnesium stearate. For Espa-Lipon's injections contains in one ampoule of solution 300 and 600 mg of active ingredient.

Pharmacological action of Espa-Lipon

According to the instruction to Espa-Lipon, drug has disintoxication, hypoglycemic, gipokholesterinemichesky and hepatoprotective activity, taking part in adjustment of a metabolism. The thioctic acid which is Espa-Lipon's part participates in oxidizing reactions of alpha ketonic acids and pyruvic acid, improves work of a liver, promotes cholesterol exchange stimulation.

In the nature of action thioctic acid is similar to group vitamins V. Espa-Lipon promotes increase in a glycogen in liver cells, to decrease in concentration of glucose in blood, to overcoming disturbance of a susceptibility of cells to effect of insulin. Drug promotes removal of toxins from an organism, protects liver cells from influence of toxic substances, protects body at poisoning with salts of heavy metals.

Neurotyre-tread action of Espa-Lipon consists in inhibition of peroxide oxidation of lipids in nervous tissue, activation of an endoneural blood-groove, simplification of process of carrying out nervous impulses on cells.

Administration of drug by the patients having motor neuropathy, according to reviews to Espa-Lipon provokes emergence of a large number of makroergichesky connections in muscles.

At oral administration Espa-Lipon is well and quickly soaked up from a GIT, and the simultaneous use of means with food reduces the speed and quality of absorption of drug.

Metabolization of thioctic acid is carried out by conjugation and oxidation of side chains. Active agent of Espa-Lipon with urine in the form of metabolites is removed. A medicine elimination half-life from a blood plasma – 10-20 minutes.

Espa-Lipon has effect of "the first passing" through a liver – that is active properties of drug partially decrease under the influence of the natural defender from the alien substances coming to an organism.

Indications to Espa-Lipon's use

According to the instruction Espa-Lipon is appointed at the following conditions of patients:

  • Polyneuropathy (including diabetic and alcoholic etiologies);
  • Liver diseases (including cirrhosis and chronic hepatitis);
  • The chronic or acute intoxications connected with poisoning with salts of heavy metals, mushrooms and so forth.

Also drug is effective concerning atherosclerosis, being applied to treatment and prevention of a disease of arteries.

Contraindications

Espa-Lipon is not appointed to the patients suffering from chronic alcohol addiction, a glucose galactose sprue and also the persons having deficit of lactase in an organism.

With care Espa-Lipon's reception is recommended by a sick diabetes mellitus – at obligatory correction of a dose of gipoglikemiziruyushchy means. It is not necessary to perform treatment by Espa-Lipon to children up to 18 years – because of lack of data on safety of use of means for this category of patients. In case of existence of important indications administration of drug by persons of this age group can strictly be carried out according to the recommendation of the doctor, taking into account an individual dosage.

Also full safety of Espa-Lipon for health of a fruit at administration of drug is not proved during pregnancy. In need of treatment of the woman by Espa-Lipon during a lactation it is necessary to resolve an issue of a temporary excommunication of the baby from a breast.

Side effects of Espa-Lipon

According to responses Espa-Lipon is well had by an organism, however, in isolated cases perhaps emergence of the following side effects:

  • Nausea, vomiting, headache, the complicated breath;
  • The increased sweating, spasms;
  • Allergic reactions in the form of eczema, a small tortoiseshell, hemorrhagic rash and an acute anaphylaxis.

The patients having Ампулы Эспа-Липонperipheral polyneuropathy can feel feeling of "goosebumps" on skin at the beginning of therapy. At bystry intravenous administration of drug increase in intracranial pressure, dot hemorrhages in skin and mucous membranes, a vision disorder is possible.

Medicinal interaction

The concomitant use of Espa-Lipon with peroral hypoglycemic drugs and insulin can provoke strengthening of hypoglycemic effect – increase in sensitivity of peripheral body tissues to insulin.

Espa-Lipon's use according to the instruction together with alcohol reduces activity of thioctic acid. During treatment drug recommends to refrain from reception of the means containing ethanol and alcoholic beverages.

Besides, activity of thioctic acid concerning binding of metals therefore Espa-Lipon's reception along with the medicines containing ions of iron, calcium, magnesium is possible with observance of a two-hour interval between administrations of drugs is revealed.

Espa-Lipon's reception with Cisplatinum reduces medicinal efficiency of the last.

Route of administration

The coated pill is taken inside, orally, without chewing and without crushing. For convenience of use it is possible to wash down medicine with simple water.

Solution for intravenous administration is prepared from the concentrate divorced in isotonic solution of sodium of chloride.

At diabetic polyneuropathy 600 mg of means once a day or on 200 mg of drug 2-3 times a day are appointed.

At a severe form of diabetic polyneuropathy the dosage of 600 mg of drug 3 times a day is applied.

Espa-Lipon's dose and duration of a course of treatment depends on character and the course of a disease, and also personal features of an organism of the patient. The optimum dosage of drug is selected only the doctor.

Reviews to Espa-Lipon of overdose by drug did not arrive. At reception of medicine in much the quantities exceeding the recommended dose emergence of nausea, headache and vomiting is possible. As the specific antidote of Espa-Lipon does not exist, treatment of this state is performed symptomatic.

Attention! This instruction to Espa-Lipon is submitted in the fact-finding purposes. Before use of drug consult with the doctor!

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Espa-Lipon solution 600 of Mg of 24 Ml 5 pieces

718 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Espa-Lipon solution for инъ konts.25mg/ml 24 ml No. 5, Esparma

750 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC

Espa-Lipon N10 SOLUTION 300mg/12ml

787 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Espa-Lipon solution for инъ konts.25mg/ml 12 ml No. 10, Esparma

809 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC
 
 
Whether you know that:

The most rare disease – a disease the Kura. Only representatives of the tribe Faure in New Guinea are ill it. The patient dies of laughter. It is considered that eating of a human brain is an origin of a disease.