KALTSIY-D3 NIKOMED

Kaltsy-D3 Nikomed – the regulator of calcium-phosphorus exchange compensating for the deficiency of an organism of calcium and D3 vitamin.

Kaltsy-D3 Nikomed treats pharmacological groups of proofreaders of metabolism of a cartilaginous and bone tissue in combinations, to vitamins and vitaminopodobny means in combinations.

Pharmacological action

Kaltsy-D3 Nikomed – drug of a combination of calcium and D3 vitamin (cholecalciferol), is necessary in a case:

• Regulation of phosphorus-calcium exchange;
• Completions of deficit of calcium in hair, teeth, muscles, bones, nails;
• Decrease in a resorption (rassasyvaniye) and increase in density of bone tissues;
• Completions of deficit of calcium and D3 vitamin necessary for a mineralization of teeth;
• Regulation of muscular contractions, nerve conduction;
• Normalization of coagulability of blood;
• Decrease in production of the parathyroid hormone stimulating washing away of calcium from bones.

D3 vitamin in drug promotes increase in absorbability and distribution of calcium in fabrics and bodies. Coming to an organism, components of drug are absorbed by digestive tract: D3 vitamin – a small intestine, calcium – proximal department of a small intestine. Biological availability of calcium in the drug Kaltsy-D3 Nikomed about 30%. In extracellular space and in cells about 1% of calcium is distributed, other calcium is distributed in a bone tissue. D3 vitamin is partially metabolized by a liver, turning into calcitriol (an active metabolite).

Active components of drug through kidneys and digestive tract are removed from an organism, in addition calcium is removed through sweat glands.

Form of release Kaltsy-D3 Nikomed

Kaltsy-D3 Nikomed – a round form chewable tablets, white color, biconvex, without cover, are possible uneven edges and small impregnations:

• Tablets with an orange flavor – 20, 50, 100 pieces. A plastic bottle in cardboard packaging;
• Tablets with menthol taste – 20, 50, 100 pieces. A plastic bottle in cardboard packaging;
• Tablets with taste of a lemon (Kaltsy-D3 Nikomed Forte) – 30, 60, 120 pieces. A plastic bottle in cardboard packaging.

Analogs of Kaltsy-D3 Nikomed

Analogs of Kaltsy-D3 Nikomed on active component – Calcium + D3 vitamin Vitrum, Kaltsy-D3-MICK, D3 Calcium complivit, Natekal of D3, Revital D3 Calcium, D3 Calcium the Classic.

Drug analogs on the influence mechanism – Vitrum Osteomag, Kalkokhel (homeopathic), Kaltsemin, Kaltsemin Advans, Kaltsy-D3 Aktavis.

Indications to use of Kaltsy-D3 Nikomed

According to the instruction, Kaltsy-D3 Nikomed is appointed for treatment and prevention of a lack of an organism of calcium and D3 vitamin in a case:

• Osteoporosis (menopauzny, steroid, senile, idiopathic, etc.) for prevention and in a complex with the main treatment;
• Osteomalacy – a softening of bones as a result of disturbance of mineral exchange;
• Hypocalcemias – at decrease in content in blood serum of the ionized calcium;
• The increased need of an organism for drug components – the period of intensive growth of children after 12 years.

Kaltsy-D3 Nikomed at pregnancy

According to the instruction, Kaltsy-D3 Nikomed at pregnancy and feeding by a breast is recommended to accept for completion of deficit of D3 vitamin and calcium. The hypercalcemia owing to overdose of drug can exert adverse impact on fetation. The maximum daily dose of components of drug – calcium of 1500 mg, and D3 600 ME vitamin.

Drug can be accepted during a lactation, but it is necessary to know that cholecalciferol and calcium are capable to get into breast milk. For calculation of a daily dose of drug in that case it is necessary to consider also other sources of these components in an organism of mother and child.

Kaltsy-D3 Nikomed at pregnancy and feeding by a breast it is necessary to accept only to destination the attending physician and under his control.

Contraindications

According to the instruction, Kaltsy-D3 Nikomed do not appoint in a case:

• The increased individual sensitivity to drug components, a peanut and soy;
• D3 hypervitaminosis;
• Hypercalcemias;
• Hypercalcurias;
• Nefrotiliaza;
• The expressed renal failure;
• Active form of tuberculosis;
• Fenilketonuriya;
• Sarcoidosis;
• Hereditary intolerance of fructose;
• Glyukozo-galaktozny malabsorption;
• Sakharazno-izomaltazny insufficiency.

With care it is necessary to appoint Kaltsy-D3 Nikomed at a moderate renal failure, by force to motionless patients, elderly people, children aged up to 12 years.

Route of administration of Kaltsy-D3 Nikomed

According to the instruction, Kaltsy-D3 Nikomed accept orally, chewing or swallowing entirely. Adults and children after 12 years 1 tablet 2 times a day in the morning and in the evening during meal or according to the scheme appointed by the attending physician taking into account specific features of an organism.

Medicinal interaction

According to the instruction, Kaltsy-D3 Nikomed at a concomitant use as follows interacts with such drugs:

• Cardiac glycosides – drug exponentiates toxic effects of glycosides at a hypercalcemia. Control of content of calcium in blood serum and an ECG is necessary;
• Tetracycline drugs – calcium reduces their absorption from a GIT. It is necessary to accept tetracyclines in 2 hours prior to or 4-6 hours later after administration of drug;
• Bisfosfonata – calcium reduces their absorption. To accept not less than for an hour to drug;
• GKS – reduce absorbability of calcium. Increase in a dose of drug is possible;
• Diuretics of a thiazide row – increase risk of a hypercalcemia. Regular control of calcium in blood serum is necessary;
• Left thyroxine – calcium reduces its absorption. A gap between administrations of drugs not less than 4 hours;
• Antibiotics of group of hinolon – calcium reduces their absorption. Are accepted in 2 hours prior to or 4 hours later after administration of drug.

Absorbability of calcium reduces reception of foodstuff with the maintenance of oxalates and phytin. Therefore, according to the instruction, Kaltsy-D3 Nikomed can be accepted in 2 hours after consumption of grain, spinach, a sorrel, a rhubarb.

Side effects

At reception of Kaltsy-D3 Nikomed, according to reviews, the stomach ache, nausea, diarrhea, a meteorism, locks are possible. Uncontrollable administration of drug can sometimes become the reason of a hypercalcemia or a hypercalcuria.

At strong overdose of Kaltsy-D3 Nikomed, according to reviews, can cause thirst, a polyuria, a loss of appetite, nausea, vomiting, locks, a headache, weakness, dizziness, unconscious states. At prolonged use formation of calcification of vessels and fabrics is possible.

Storage conditions

Kaltsy-D3 Nikomed is stored at the room temperature, in the dry place unavailable to hit of direct sunshine.

Period of validity – 3 years of date on packaging.