Curantyl

Curantyl – the drug used for the purpose of improvement of blood circulation, the prevention of a thrombogenesis and recovery of immunity.

Pharmacological action

Curantyl is active agent Dipiridamolum by which action are caused antiagregantny (interferes with a thrombogenesis), vazodilatiruyushchy (expands vessels) and immunomodulatory properties of drug.

Use Curantyl allows to expand heart vessels, to increase the speed and volume of a blood-groove, to improve supply of a myocardium with oxygen. Drug interferes with formation of blood clots that causes efficiency of drug at many cardiovascular diseases.

Use Curantyl at pregnancy is connected with ability of drug to prevent obstruction of blood vessels of a placenta that allows to avoid many heavy complications connected with a hypoxia (a lack of oxygen) of a fruit.

The immunomodulatory effect Curantyl is expressed in ability of drug to excite synthesis of interferon and to increase its activity that is of great importance at prevention and treatment of viral diseases, including flu.

The maximum concentration Curantyl is observed in an hour after reception of its peroral forms.

Indications to Curantyl use

The instruction recommends to appoint Curantyl at:

• disturbances of blood circulation of a brain on ischemic type;
• distsirkulyatorny encephalopathy;
• to prevention of venous and arterial thromboses, and also at treatment of their complications;
• to prevention of coronary heart disease, especially, so far as concerns intolerance of acetylsalicylic acid;
• the prevention of a thromboembolism after the undergone operation on prosthetics of heart valves;
• disturbances of a mikrutsirkulyation, as part of complex therapy;
• viral diseases, SARS, flu.

Responses characterize curantyl as the effective drug used at the complicated pregnancy for the purpose of the prevention of placental insufficiency.

Contraindications

Curantyl, use assumes familiarity with the instruction, is not appointed at:

• unstable stenocardia;
• acute myocardial infarction;
• the widespread stenosing atherosclerosis of coronary arteries;
• heart failure in a decompensation stage;
• subaortal stenosis of an aorta;
• arterial hypotension;
• heavy arterial hypertension;
• collapse;
• heavy disturbances of a cordial rhythm;
• chronic renal failure;
• chronic obstructive diseases of lungs;
• liver failure;
• hemorrhagic diathesis;
• diseases at which development of bleeding is possible;
• hypersensitivity to Dipiridamolum or auxiliary components of drug.

As responses and clinical trials refer Curantyl to category of rather safe drugs, its use during pregnancy and in the period of a lactation perhaps only according to indications.

Application instruction of Curantyl

Curantyl 25 is represented by the dragees containing 25 mg of Dipiridamolum. Tablets, coated, are presented by the drugs Curantyl 25 and Curantyl 75 which numbers in the name correspond to amount of active ingredient in them. Drug is accepted on an empty stomach, without crushing, washing down with water. The doses recommended by the instruction to Curantyl are counted on adults and children 12 years are more senior.

At drug Curantyl coronary heart disease the instruction recommends to accept 75 mg 3 times a day. If necessary the daily dose can be modified by the doctor towards increase. Disturbances of cerebral circulation assume use Curantyl of 3-6 times a day on 75 mg, at the same time the daily dose should not exceed 450 mg. For the purpose of reduction of aggregation of thrombocytes usually in days appoint 75-225 mg of drug, if necessary the daily dose Curantyl can be increased to 600 mg.

Curantyl 25 and Curantyl 75 is recommended to be accepted for prevention of a SARS and flu according to the following scheme: within 4-5 weeks once a week at one time take 2 pill or 2 dragees. The prevention of a recurrence of viral infections, including SARS, assumes reception Curantyl 25 and Curantyl 75 according to the scheme: within 8-10 weeks once a week accept 2 units of drug twice a day with an interval between receptions at 2 o'clock.

The scheme of reception Curantyl at pregnancy is defined by the doctor.

It is necessary to know that the use of tea or coffee reduces efficiency Curantyl while acetylsalicylic acid on the contrary strengthens effect of drug.

Side effects

Responses and clinical trials refer Curantyl to undesirable effects:

• tachycardia, heartbeat, bradycardia, lowering of arterial pressure, dermahemia of the person, rushes of blood to the person;
• diarrhea, vomiting, nausea, pains in epigastric area;
• thrombocytopenia, bleedings, the raised bleeding in time or after operations;
• headache, sonitus, dizziness;
• urticaria, skin rash;
• rhinitis, mialgiya, arthritis, ear congestion, weakness.

Additional information

The instruction recommends to store Curantyl at a temperature which is not exceeding ^300C.

Period of validity Curantyl of 25 - 5 years, drug in the form of tablets – 3 years.