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Naproxenum

Application instruction:

Form of release and structure

Indications to use

Contraindications

Route of administration and dosage

Side effects

Special instructions

Medicinal interaction

Terms and storage conditions

The prices in Internet drugstores:

from 222 rub.

In more detail

Naproxenum – drug with febrifugal, analgeziruyushchy and antiinflammatory action.

Form of release and structure

Naproxenum is released in the form of tablets (on 50 pieces in dark glass bottles, on 1 bottle in a cardboard pack; on 10 pieces in blisters, on 5 (on 250 mg) or 2 blisters (500 mg) in a cardboard pack).

Active agent is a part of 1 tablet: Naproxenum – 250 or 500 mg.

Indications to use

Primary dysmenorrhea;
Joint syndrome at rheumatism;
Periarthritis;
Pseudorheumatism;
Ankylosing spondylarthritis;
Injuries and inflammatory diseases of soft tissues and musculoskeletal system;
Gout;
Osteoarthrosis;
The feverish states connected with infectious and inflammatory diseases.

Contraindications

Aggravation of a peptic ulcer of a stomach and duodenum;
The bronchospasm attacks connected using non-steroidal anti-inflammatory drugs in the anamnesis;
Hemorrhagic diathesis;
Pregnancy and period of a lactation;
Hypersensitivity to drug components.

Route of administration and dosage

Naproxenum is accepted inside, it is more preferable – during food.

In an initiation of treatment and at acute states the adult drug appoint in a daily dose 500-1000 mg, frequency rate of reception – 2 times a day (in morning and evening). The maintenance dose makes 500 mg a day in 1 or 2 receptions. At bad attacks of gout accept once 750 mg of Naproxenum, then for 2-3 days each 8 hours on 250-500 mg.

To children drug is appointed on 5 mg/kg by each 12 hours.

Side effects

During use of Naproxenum the disturbances which are shown in the form of vomiting, heartburn, nausea, a lock or diarrhea, pains in epigastric area, a headache, disturbances of concentration of attention, a disorientation, a depression, vision disorders, skin and allergic reactions, hemorrhages can develop.

Special instructions

To and during use of Naproxenum (in particular long) it is necessary to investigate function of kidneys regularly.

During therapy it is necessary to consider that drug increases a bleeding time.

Medicinal interaction

At joint purpose of Naproxenum with some medicines there can be following effects:

Indirect anticoagulants: insignificant strengthening of their action;
The antacids containing aluminum and magnesium, hydrosodium carbonate: decrease in absorption of Naproxenum;
Amoxicillin: development of a nephrotic syndrome;
Diazepam: change of its pharmacokinetic parameters;
Salicylamidum: strengthening of its action;
Acetylsalicylic acid, пробенецид: decrease in concentration of Naproxenum in a blood plasma;
Methotrexate: strengthening of its toxicity;
Lithium carbonate: increase in concentration of lithium in a blood plasma;
Morphine: development of a myoclonus;
Caffeine: strengthening of action of Naproxenum;
Prednisolonum: substantial increase of its concentration in a blood plasma;
Furosemide: reduction of its diuretic action.

Terms and storage conditions

To store in protected from light, the place, dry, unavailable to children, at a temperature up to 25 °C.

Period of validity – 3 years.

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Naproxenum тбл 250 mg No. 30, HFK (г.Москва) Quinacrine

222 rub.

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