Sedalit

Sedalit – normotimichesky medicine with anti-maniacal and antidepressive action.

Pharmacological action of Sedalit

Active agent of Sedalit has sedative, antidepressive and anti-maniacal effect, and also normalizes a mental state, without causing at the same time the general block.

Ions of lithium reduce bioelectric activity of neurons of a brain and have favorable effect at migraine (that is caused by change of concentration of serotonin) and depressions.

Release form

Sedalit release in the form of capsules and coated tablets containing 300 mg of active agent – carbonate lithium. On 50 pieces in packaging.

Sedalit's analog is the drug Micalitum in the form of capsules.

Indications to Sedalit's use

According to the instruction indications to Sedalit's use are:

• Hypomaniacal and maniacal conditions of various genesis;
• Affective frustration at alcoholism;
• Affective psychoses, including maniac-depressive and schizoaffective.

Besides, Sedalit is shown to use at:

• Migraines;
• Sexual frustration;
• Menyer's syndrome;
• Some forms of medicinal dependence.

Sedalit's contraindications

Sedalit according to the instruction contraindicated to apply in the following cases:

• In states after heavy operative measures;
• At pregnancy;
• At a leukosis;
• In the period of a lactation;
• At hypersensitivity to Sedalit's components.

With care appoint Sedalit at:

• Diseases of cardiovascular system, including AV blockade and intra ventricular blockade;
• Parkinsonism;
• Thyrotoxicosis;
• Psoriasis;
• To ischuria;
• Epilepsies;
• Diabetes mellitus;
• Hyperparathyreosis;
• Renal failure;
• Disturbance of water and electrolytic exchange, including an electrolyte-deficient diet, simultaneous treatment by diuretics, vomiting or diarrhea.

Sedalit route of administration

The initial dose of Sedalit according to the instruction can fluctuate from 0,6 g to 1,2 g a day divided into several receptions. The last single dose should be accepted before going to bed.

Gradually day dosage is increased to optimum (as much as possible – 2,4 g). Treatment duration (in doses more than 2 g a day) should not exceed two weeks.

After disappearance of symptoms of a disease the dosage is gradually reduced to preventive which corresponds to initial.

Treatment by Sedalit according to the instruction should be carried out under control of concentration of Li + to blood (normal – 0,4-0,8 mmol/l) for not less than half a year.

At the carried-out therapy it is necessary to consider that Sedalit according to the instruction reduces antidiuretic effect of desmopressin, carbamazepine, hormones of a back share of a hypophysis, lypressin, and also the central promoting effect of amphetamines.

Molindon at simultaneous use with Sedalit according to reviews stimulates development of a neurotoxicity that can lead to development of a delirium, pathological changes of EEG, confusion of consciousness, epileptic seizures and noctambulation.

Blockers of slow calcium channels at joint therapy with Sedalit can increase the frequency of emergence of such neurotoxic complications as nausea, an ataxy, a tremor, vomiting, a sonitus and diarrhea.

The risk of increase in body weight increases at a concomitant use of Sedalit with antipsychotic medicines, neuroleptics and timoleptika.

Besides, administration of drug of Sedalit is incompatible with etanolsoderzhashchy drinks.

Side effects

According to Sedalit in certain cases leads to development of undesirable side effects in a look:

• Myasthenias;
• Adynamias;
• Polydipsia;
• Braking of a hemogenesis;
• Leukocytosis;
• Discomfort;
• Acne;
• Tremor of hands;
• The Dispepsichesky phenomena – nausea, vomitings, diarrheas;
• Disturbances of a cordial rhythm;
• Alopecias;
• Pyodermas;
• Hypothyroidism;
• Drowsiness;
• Arrhythmias;
• Increases in body weight;
• Dryness in a mouth.

Drowsiness, diarrhea, muscular weakness, appetite loss, nausea, dysarthtia, vomiting, tremor according to reviews belong to early symptoms of overdose by Sedalit.

If in time the treatment including introduction of a large amount of liquid and Na+ was not carried out later symptoms can develop. Treat them:

• Dizziness;
• Incoordination;
• The confused consciousness;
• Illegibility of visual perception;
• Polyuria;
• Heavy spasms.

Sedalit storage conditions

Sedalit treats a number of psychotropic prescription medicines with a period of storage of 36 months.