Atakand

Atakand – the combined drug used for treatment of arterial hypertension and heart failure.

Form of release and structure

Atakand produce in the form of round light pink tablets (14 pieces in the blister, on 2 blisters in a cardboard pack).

Active ingredient: tsileksetit a kandesartan, in 1 tablet – 8, 16 and 32 mg.

Excipients: karmelloza of calcium, magnesium stearate, hypro rod, iron dye dioxide red, lactoses monohydrate, macrogoal, starch corn.

Indications to use

• Arterial hypertension;
• Heart failure and disturbance of systolic function of a left ventricle (apply as additional therapy to APF inhibitors, or in cases of their intolerance).

Contraindications

• Abnormal liver functions or cholestasia;
• Hypersensitivity to active ingredient or other components of tablets;
• Pregnancy and period of a lactation.

This medicine should be taken with caution:

• The expressed renal failure;
• Bilateral stenosis of renal arteries;
• Cerebrovascular diseases and coronary heart disease;
• Renal transplantation in the anamnesis;
• Age up to 18 years.

Route of administration and dosage

Pill Atakand is taken irrespective of meal once a day.

At arterial hypertension the initial and supported dose, irrespective of age, make 8 mg a day, in certain cases – 16 mg. If the carried-out therapy does not lead to a lowering of arterial pressure, combined use of Atakand with thiazide diuretic is recommended. Easy and moderate disturbances of functions of kidneys of dose adjustment do not demand. At an abnormal liver function easy and moderate severity the initial dose should not exceed 2 mg a day. The maximum anti-hypertensive effect at treatment by drug is reached within a month from an initiation of treatment.

At heart failure it is necessary to accept drug on 4 mg a day in an initiation of treatment, afterwards it is possible to double a dose each two weeks (to 32 mg a day). Atakand is effective at simultaneous use with other drugs from chronic heart failure – beta adrenoblockers, APF inhibitors, cardiac glycosides and diuretics.

At advanced age and the patient with a renal failure correction of an initial dose of medicine is not required.

Side effects

Atakand is usually had well.

The side effects arising at administration of drug do not depend on age and the accepted dose.

At treatment of arterial hypertension weakness, dizziness, respiratory infections, a headache, a dorsodynia most often develop.

At complex treatment of chronic heart failure Atakand can cause: the expressed lowering of arterial pressure, a leukopenia, a neutropenia, an agranulocytosis, a renal failure, a Quincke's disease, a hyperpotassemia, a hyponatremia, an arthralgia, nausea, weakness, dizziness, a headache, a mialgiya, a dorsodynia, a small tortoiseshell, a skin itch, rash.

Dizziness and the expressed arterial hypotension belong to the main symptoms of overdose by Atakand.

Special instructions

Therapy kandesartany can negatively influence function of kidneys. In case of a renal failure it is necessary to control indicators of their work regularly. Such control is also necessary at treatment of myocardial insufficiency.

Calibration of medical doses is obligatory at the weakened myocardial function at patients with pathologies of kidneys (at the overestimated level in calcium blood, and in combination with APF inhibitors) as in such cases administration of drug promotes increase in risk of complications.

Atakand's use can cause a kidney artery stenosis, hypotension (in case of myocardial insufficiency), a hypovolemia.

If against the background of reception of a kandesartan surgery and use of anesthetics is planned, it is necessary to consider risk of display of hypotension.

When the daily dose in 32 mg does not give desirable effect, the attending physician has to make the decision on further expediency of use of drug.

To patients with a hyper aldosteronism of a tablet are not appointed as effectiveness of therapy by this group of means at them is absent.

Drug should be cancelled right after pregnancy diagnosing.

Atakand does not influence ability to drive the car and to work with difficult mechanisms, but it is necessary to remember that probable side effects in the form of weakness, the increased fatigue and dizziness can be shown.

Analogs

Direct analogs of drug, in which the main active ingredient – кандесартан: Angiakand, Kandekor, Kandesar, Giposart, Ordiss, Kandesartan-SZ.

The medicines close on the influence mechanism: Aprovel, Bloktran, Brozaar, Vazotenz, Valsakor, Diovan, Zisakar, Ibertan, Kardosten, Lozap, Lorista, Mikardis, Naviten, Prezartan, Teveten, Firmasta, Irsar, Edarbi, etc.

Terms and storage conditions

Atakand treats drugs of the list "B" and is released according to the medical recipe.

The recommended period of storage – 3 years, at a temperature up to 30 °C, in the place unavailable to children protected from light.