Цетиринакс
Application instruction:
Цетиринакс – antiallergic medicine. Blocker histamine H1 receptors.
Structure and form of release of Tsetirinaks
Drug is produced in the form of the ellipse, biconvex tablets of white color containing 10 mg of a tsetirizin of dihydrochloride everyone.
Additional components: microcrystallic cellulose, magnesium stearate, monohydrate of lactose, colloid silicon dioxide, кросповидон.
On 7 tablets in packaging.
Pharmacological action
According to the instruction of Tsetirinaks H1 receptors are a blocker histamine. Hydroxyzinum metabolite, competitive antagonist of a histamine.
Цетиринакс facilitates the course of an allergy and prevents its development. At a late stage of allergic reactions slows down release of mediators, reduces migration of eosinophils, basophiles and neutrophils. Influences an early stage of allergic reactions, makes the expressed anti-exudative and antipruritic impact.
Removes a spasm of smooth muscles and hypostasis of fabrics, reduces permeability of capillaries. In the recommended dosages of Tsetirinaks has practically no antiserotoninovy and anticholinergic effect, and in therapeutic doses does not make sedative impact on an organism.
According to Tsetirinaks begins to work an hour later at 95% of patients. Other 5% noted the beginning of effect of drug in 20 minutes after reception. Duration of action makes one days.
After the therapy termination effect of drug remains for several days.
Route of administration of Tsetirinaks and mode of dosing
According to the instruction of Tsetirinaks it is intended for intake. Tablets are washed down with a small amount of liquid.
As a rule, children are more senior than six years and adults accept drug on one tablet once a day, it is more preferable in the evening. Also administration of drug twice a day is allowed (0,5 tablets in the morning and 0,5 – in the evening).
To patients with a renal failure, as a rule, appoint Tsetirinaks according to the instruction in a dosage 0,5 tablets a day. And at a chronic renal failure the dosage makes 0,5 tablets every other day.
Indications to use of Tsetirinaks
According to the instruction of Tsetirinaks appoint in the following cases:
- hay fever (pollinosis);
- small tortoiseshell;
- the allergic dermatosis which is followed by a severe itch;
- Quincke's disease;
- chronic or seasonal allergic conjunctivitis and rhinitis.
Contraindications
Цетиринакс it is contraindicated in the following cases:
- age up to six years;
- pregnancy and breastfeeding;
- hypersensitivity to one or several components of drug.
With care appoint Tsetirinaks to patients of old age, and also at a chronic renal failure.
Side effects of Tsetirinaks
According to Tsetirinaks it is preferential positively transferred by patients and quite seldom causes by-effects. The following reactions from various systems of an organism are sometimes possible:
- dizziness, migraine, headache;
- discomfort in a stomach, dryness in a mouth;
- Quincke's disease, skin rash and itch, small tortoiseshell.
Overdose
At a single dose of Tsetirinaks in a dosage of 50 mg and more drowsiness, irritability, dryness in a mouth, a lock, an urination delay, concern can develop.
In this case it is necessary to make a gastric lavage, to accept adsorbents and to carry out a symptomatic treatment.
Tsetirinaks storage conditions
Цетиринакс store in the dry place at the room temperature not longer than 36 months.
Special instructions
At Tsetirinaks's reception in a dosage more than 10 mg a day are noted decline in the ability to bystry reactions.
Against the background of administration of drug it is not recommended to take alcoholic drinks.
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