Citramonum

Citramonum is the medicine relating to group of non-steroidal anti-inflammatory drugs.

Pharmacological action

Several active ingredients (the combined drug) are a part of Citramonum. Therefore its pharmacological action is defined by mutual influence of each active component:

• Acetylsalicylic acid – renders antiinflammatory and febrifugal effects, stops the pain caused by an inflammation to some extent reduces coagulability of blood and improves blood circulation in the center of inflammatory process;

• Caffeine – has exciting effect on the central nervous system and its psychomotor centers, expands a gleam of blood vessels, reduces drowsiness, feeling of fatigue, possesses the insignificant anesthetizing action, stimulates intellectual and physical activity;

• Paracetamol – the drug having the analgetic, febrifugal and moderately expressed antiinflammatory properties.

Indications to use

According to the instruction Citramonum is shown for stopping of moderate expressiveness of the pain syndromes caused by various reasons:

• Dentagra;

• Headache;

• Mialgiya;

• Arthralgia;

• Neuralgia.

Indications to Citramonum are also feverish states and painful periods.

Citramonum route of administration

Citramonum is usually appointed on one tablet by three times a day. In many cases one reception of Citramonum for stopping of a pain syndrome suffices.

Side effects

According to the instruction Citramonum can lead to development of side effects from various bodies and systems:

• Nausea and vomiting, pains in the field of an epigastrium. At prolonged use of Citramonum development of erosive gastritis and disturbances of functions of a liver is possible;

• Decrease in coagulability of blood, strengthening of a bleeding time;

• Dizziness, strengthening of a headache;

• Renal failure.

Use of Citramonum can also lead to development of the most various allergic reactions:

• Skin rash and itch;

• Small tortoiseshell;

• Stephens-Johnson's syndrome (exudative malignant erythema);

• Lyell's disease (epidermal toxic necrolysis);

• Acute anaphylaxis;

• Ray's syndrome (at children).

According to the instruction Citramonum can also lead to deterioration in sight and emergence of a sonitus.

Contraindications

This medicine cannot be used in the following cases:

• The increased individual sensitivity;

• Hemophilia;

• Heavy arterial hypertension;

• Erosive gastritis and peptic ulcer;

• Hemorrhagic diathesis;

• Portal hypertensia;

• Liver or renal failure;

• Heavy course of coronary heart disease and atherosclerosis of vessels of a brain.

Citramonum is contraindicated also for use in pediatric practice. It children cannot appoint younger than 15 years because of risk of development of Ray's syndrome at them. Also Citramonum is contraindicated during preparation for operative measures since it raises bleeding.

Use of Citramonum during pregnancy

Citramonum is contraindicated in the first and third trimester of pregnancy. The acetylsalicylic acid which is its part possesses teratogenic action that can lead to development of congenital anomalies of a fruit. Reception of Citramonum in the third trimester promotes premature closing of an aortal channel and increases risk of bleeding in labor. In the second trimester of the indication to Citramonum have to be estimated by the doctor carefully. Drug can be used only when the estimated advantage of the carried-out treatment significantly exceeds potential risk of impact on fetation.

Interaction with other drugs

Citramonum is capable to strengthen effect of hypoglycemic and steroid drugs, indirect anticoagulants. At its joint reception with the Methotrexate and other non-steroidal anti-inflammatory drugs the risk of development of side effects sharply increases. According to the instruction it is inadmissible to appoint Citramonum along with antiepileptic drugs, Rifampicin and barbiturates since in this case in a large number there is a formation of hepatotoxic metabolites.

Structure of Citramonum and form of release

Citramonum is issued in the form of tablets in packaging on 6 and 10 pieces. Are a part of Citramonum: Caffeine (30 mg), Paracetamol (180 mg) and Acetylsalicylic acid (240 mg).

Storage conditions

Drug should be stored in the dry place unavailable to children at room temperature.