Fermenkol

Fermenkol-fermentny anticicatricial cosmetic drug of new generation. Reviews of Fermenkola confirm high medical performance and speed of drug.

Drugs of Kontratubeks, Lidaz – Fermenkol's analogs.

Structure and form of release

Fermenkol represents unique enzymatic composition from 9 collagenolytic proteases with a molecular weight from 20 to 100kda, the sea invertebrates received from digestive organs.

Drug does not contain additional impurity (pigments, polysaccharides, lipoproteids).

The following forms of release of Fermenkol are known:

• the set for an electrophoresis including a complex of collagenases in the form of dry active agent - hygroscopic powder of light yellow color (4 mg), and also a solaktin – special means in the form of transparent liquid for preparation of solution of enzymes (40 ml).
• Fermenkol in the form of gel (transparent weight). One gram of gel contains 0,1 mg of a complex of collagenases - the main active ingredient of drug.

Pharmacological action of Fermenkol

According to the instruction Fermenkol shows both the general proteolytic, and collagenolytic activity. Fermenkol has ability to hydrolyze on separate amino acids characteristic for hypertrophic and keloid cicatrixes branched molecules of pathological collagen with vortex and nodal laying. Destruction of excess collagen is resulted by recovery of structure and water and electrolytic balance of cicatricial fabric.

Indications to Fermenkol's use

Reviews of Fermenkola confirm that the medicine can be applied to correction of hems and prevention of their development in various fields of cosmetology and surgery (postburn and postoperative hems, treatment of an acne, and also correction of effects of an acne).

According to the instruction Fermenkol it is necessary to use in three weeks after a burn, an injury or an operative measure.

Fermenkol route of administration according to the instruction

The drug can be administered in cicatricial fabric by means of application, a fonoforez and an electrophoresis.

Application – the most available method of use of Fermenkol in house conditions. For holding this procedure Fermenkol in the form of powder it is necessary to dissolve in 40-50 ml of normal saline solution or the distilled water. The napkin moistened with the received solution should be put on area of a hem approximately for half an hour. It is necessary to carry out the procedure one - twice a day for a month. If necessary to repeat a course of treatment.

Before Fermenkol's use in the form of gel it is necessary to clear the damaged site of skin special cosmetic. To apply with the easy movements gel (not to rub). This procedure it is necessary to carry out two-three times a day for a month. A break between courses of-10-16 days.

Judging by reviews of Fermenkola, the best results in treatment are observed at administration of drug by means of a fonoforez or an electrophoresis.

At a fonoforeza all conditions for deeper penetration of collagenolytic enzymes into affected areas of skin are created. Before the procedure it is necessary to clear the site of skin special cosmetic. Introduction mode: density of an energy flow is no more than 300 MW/cm ² at a fonoforeza in extremities and a trunk and no more than 200 MW/cm ² at a fonoforeza around the person. Duration of influence is about five minutes on one area. It is necessary to apply the procedure 10-12 times daily at the same time days. A break between courses of-10-16 days.

For an electrophoresis according to the instruction Fermenkol in the form of powder it is necessary to part in potassium chloride solution (1% aqueous solution) to concentration in solution 1mgml and then to dilute this solution with weak solution of hydrochloric acid. To moisten a gauze napkin with the received Fermenkol's solution (with concentration 0,2mg/ml), to impose it on area of a hem and to use for the procedure of an electrophoresis. Introduction should be begun with the anode at the density of current no more than 0,05 ¼Ç/cm ² at localization of a hem in a face, and no more than 0,1 ¼Ç/cm ² at an electrophoresis in extremities and a trunk. The procedure it is necessary primenyat10-15 time daily at the same time days. A break between courses – 10-15 days.

Contraindications to use

• atrophic and hypotrophic hems;
• individual intolerance of a collagenase.

As Fermenkol contains active enzymes, at hypersensitivity of skin drug can cause its reddening which usually takes place right after medicine phase-out. It is not recommended to use drug for correction of extensions of skin.