Karsil
Application instruction:
Karsil – the vegetable drug used at treatment of diseases of a liver.
Form of release and structure
Karsil release in the form of a dragee, coated: biconvex, an enveloping layer of brown color, internal – white, on a break – from light brown till brownish-yellow color (on 10 pieces in blisters or blister strip packagings, on 8 packagings or blisters in a cardboard pack).
Is a part of 1 dragee:
- Active agent: fruits of a thistle spotty in the form of dry extract (Silymarinum equivalent) – 35 mg;
- Auxiliary components: sorbitol, monohydrate of lactose, wheat starch, talc, povidone (коллидон 25), magnesium stearate, microcrystallic cellulose, monohydrate of a dextrose, hydrosodium carbonate.
Structure of a cover: целлацефат, глицерол, diethyl phthalate, sucrose, acacia gum, gelatin, talc, titanium dioxide, a macrogoal (PEG 6000), Broun Opalux dye (red and black iron oxide, methyl - and пропилпарагидроксибензоат, sucrose, the purified water).
Indications to use
- Toxic damages of a liver;
- Hepatitis of not virus etiology (chronic current);
- States after the postponed hepatitis;
- Liver steatosis (alcoholic and not alcoholic);
- Cirrhosis (along with other drugs).
Also Karsil appoint for prevention at chronic intoxications (including professional), long reception of medicines and alcohol.
Contraindications
- Age up to 12 years;
- Hypersensitivity to drug components.
Route of administration and dosage
Karsil accept inside, washing down with enough liquid, it is more preferable – to food.
At treatment of severe damages of a liver drug is appointed by 3 times a day on 4 dragees (a daily dose – 420 mg). In more mild cases and as it is necessary to accept a maintenance therapy 3 times a day on 1-2 dragees.
For the purpose of prevention Karsil appoint 70-105 mg (2-3 dragees) in a daily dose.
Duration of a therapeutic course – is not less than 3 months.
Side effects
As a rule, Karsil is had well. Side effects develop seldom, they have passing character and take place independently after therapy cancellation.
During Karsil's use the following side effects can develop:
- Alimentary system: seldom – dyspepsia, nausea, diarrhea;
- Allergic reactions: in some cases – rash, a skin itch;
- Others: seldom – an aggravation of vestibular disturbances, in some cases – an alopecia.
Special instructions
During therapy manifestation of estrogenopodobny action of Silymarinum is possible. In this regard the patient with hormonal disturbances (a hysteromyoma, endometriosis, a carcinoma of a prostate, uterus, mammary gland, ovaries) Karsil appoint with care.
It is necessary to consider that wheat starch is Karsil's part (can constitute danger to patients with a gluten enteropathy (Gee's disease)) and глицерол (in high doses can make the irritating impact on a mucous membrane of a stomach and cause a headache).
Medicinal interaction
At simultaneous use of Karsil with the peroral contraceptive medicines and drugs used when performing hormonal replacement therapy reduction of efficiency of the last is possible.
Karsil can strengthen effects of such drugs as vinblastine, to alprazola, diazepam, ловастатин, кетоконазол.
Terms and storage conditions
To store in protected from light, the place, dry, unavailable to children, at a temperature up to 25 °C.
Period of validity – 2 years.
Name of drug
Price
Drugstore
Karsil држ 35 mg No. 80, Pharmachim/Sopharma
381 rub.
Network of the Moscow drugstores of IFCKarsil forte капс 90 mg No. 30, Sopharma JSC
405 rub.
Network of the Moscow drugstores of IFCAntidepressant Klomipramin causes an orgasm in 5% of patients.
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