Drops are nasal: transparent, colourless or slightly painted (on 5 or 10 ml in glass bottles, on 1 bottle in a cardboard pack; on 10, 15 or 20 ml in plastic bottles droppers, on 1 bottle dropper in a cardboard pack complete with a cover a dropper or without it);
Spray nasal: the transparent, colourless or slightly painted liquid (on 10 or 15 ml in the polymeric bottles droppers which are hermetically closed by polymeric traffic jams droppers and the screwed covers on 1 bottle dropper in a cardboard pack complete with a tubule).

Nasal enters into structure of 1 ml of drops and spray:

Active agent: naphazoline – 0,5 or 1 mg;
Auxiliary components: boric acid – 20 mg, the purified water – to 1 ml.

Indications to use

Sinusitis;
Acute rhinitis;
Allergic rhinitis;
Eustachitis.

Also Naphthyzinum is applied to simplification of carrying out researches of a nasal cavity (rinoskopiya).

Contraindications

The expressed atherosclerosis;
Arterial hypertension;
Chronic rhinitis, including atrophic rhinitis;
Serious illnesses of eyes, including closed-angle glaucoma;
Hyperthyroidism (thyrotoxicosis);
Tachycardia;
Diabetes mellitus;
Simultaneous use with monoamine oxidase inhibitors and the period up to 2 weeks after the end of their use;
Age up to 18 years (for 0,1% of drops), up to 15 years (for 0,1% of spray), up to 2 years (for 0,05% of spray), till 1 year (for 0,05% of drops);
Hypersensitivity to drug components.

Naphthyzinum in the form of spray should be applied with care the patient with coronary heart disease (stenocardia), a hyperplasia of a prostate and a pheochromocytoma.

The feeding and pregnant women can apply Naphthyzinum in any dosage form only in cases if the expected advantage for health of mother is higher than potential risk for the child or a fruit.

Route of administration and dosage

In otorhinolaryngology Naphthyzinum is applied intranazalno.

The mode of dosing is defined by age (in each nasal course):

Adults and children of 15 years: 3-4 times a day on 1-3 drops or to 1 injection of spray (0,05-0,1% solution);
Children of 6-15 years: 1-3 times a day on 2 drops or to 1 injection of spray (0,05% solution);
Children of 1-6 years (for drops) and 2-6 years (for spray): 1-3 times a day on 1-2 drops or to 1 injection of spray (0,05% solution).

Children of 0,05% can dissolve spray of Naphthyzinum with the distilled water in the ratio 1:1 (to 0,025%). The dosing mode at the same time should not be changed.

The course of treatment at rhinitises should not exceed at adult 5-7 days, at children – 3 days.

With the diagnostic purpose drug is used after cleaning of a nose. In each nasal course it is necessary to dig 3-4 drops either to make 1 injection or to enter the tampon moistened in 0,05% drug solution for 1-2 minutes.

Side effects

During use of Naphthyzinum there can be side effects in the form of a headache, nausea, tachycardia, a reactive hyperemia, increase in arterial pressure, swelling of a mucous membrane of a nasal cavity.

If therapy continues more than 1 week, development of local reactions in the form of hypostasis of a mucous membrane of a nasal cavity and atrophic rhinitis is possible.

Special instructions

Naphthyzinum can have resorptive effect.

At long therapy expressiveness of vasoconstrictive action gradually goes down (the tachyphylaxis phenomenon) therefore in 5-7 days of use it is recommended to take a break for several days.

Medicinal interaction

Co-administration of Naphthyzinum with monoamine oxidase inhibitors (including the period up to 2 weeks after the end of their use) is contraindicated.

Naphthyzinum slows down absorption of mestnoanesteziruyushchy drugs (lengthening of their action when carrying out surface anesthesia).

At joint appointment with other vasoconstrictive medicines the risk of emergence of side effects increases.