Senadeksin

Senadeksin – drug of laxative action on a vegetable basis.

Pharmacological action

Active ingredient of Senadeksin are antraglikozida (sennozida And yes In) plant leaves Senna narrow-leaved and ostrolisty, known also under Senna's name Alexandria or the Alexandria leaf. Drug has a promoting effect on motility of a large intestine, irritating him receptors and

strengthening thereby a peristaltics. Interferes with absorption of water from intestines that promotes increase in laxative action, exerts impact on permeability of a wall of intestines for calcium ions. Promotes synthesis of prostaglandins.

The laxative effect of administration of drug occurs in 8-12 hours after reception that needs to be considered at Senadeksin's use.

Drug does not cause accustoming and does not break digestive processes in a stomach and a small intestine.

Form of release and structure

Medicinal substance is produced in the form of the tablets of heterogeneous brown color flavored by vanillin or chocolate.

Each tablet contains 0,07g extract of leaves of Senna + excipients (corn starch, milk sugar, talc, magnesium stearate, stearic acid, нипагин, fragrance). In packaging of 10 tablets.

Senadeksin's analogs are medicines of similar action, with the same active agent in structure: Bekunis, Gerbion Laksana, Glaksenna, Ickx-Prep, Regulaks, Regulaks Pikosulfat, Senna, Sennalaks, Senaleks, Senadum, Sennozida of A and B, Pursennid, Tisasen, Ex-Laks.

Indications to Senadeksin's use

According to the instruction Senadeksin is shown at locks acute and chronic, connected with an atony of a large intestine and its weak peristaltics. The indication to Senadeksin's use is also training of the patient for diagnostic testings or operative measures. In this case appoint this drug in the evening, and in the morning in addition cleansing enema.

According to comments on Senadeksin, he helps to prevent stagnation of fecal masses at proctal cracks, a paraproctitis and hemorrhoids – in this case use in the preventive purposes is justified it.

Application instruction of Senadeksin

Pill is taken for the night, washing down with enough water. According to the instruction Senadeksin accept as necessary, 1-2 tablets one-time, or courses for 2-3 weeks. After three weeks of reception it is necessary to take a long break, not less than 2 weeks.

Dosage:

For children over 12 years and adults on 1-2 tablets once a day, before going to bed.

To children from 6 to 12 years appoint on ½-1 to a tablet once a day, to children from a year to 6 years on 1/3 tablets. To children Senadeksin is younger than one year do not appoint.

Side effects

Comments on Senadeksin testify to him as about safe and well transferable drug. Undesirable effects of its reception happen infrequently, kolikoobrazny gripes in a stomach, a meteorism, a diarrhea belong to them.

More serious side effects are caused by drug overdose, especially at prolonged use: disturbance of electrolytic balance up to spasms and a collapse, a hamaturia (blood in urine), an albuminuria (protein in urine), an intestines melanosis, damage of an intermuscular intestinal texture. Chronic diarrhea, organism dehydration, an intestines atony develops.

For this reason Senadeksin's use as means for weight loss categorically is not recommended.

Drug breaks absorption of tetracyclines that needs to be considered at a parallel antibioticotherapia.

Senadeksin's use at pregnancy

In spite of the fact that data on undesirable effect of drug during this period are absent, Senadeksin at pregnancy and in the course of feeding by a breast it is undesirable to apply, as well as the majority of medicines. Nevertheless, under control of the doctor drug can be appointed in case of a puerperal atony of intestines.

Contraindications to Senadeksin's use

According to the instruction Senadeksin is contraindicated at the following states:

• Hypersensitivity to drug;
• Acute inflammatory processes in an abdominal cavity (appendicitis, peritonitis, any other manifestations of an acute abdomen);
• Gastrointestinal bleedings;
• Intestinal impassability of any etiology;
• The restrained hernia;
• Disturbance of electrolytic exchange, condition of an obezvozhennost;
• Uterine bleedings;
• Cystitis;
• Renal failure;
• Liver failure.

Drug with care and only at emergency is appointed in the postoperative period, at children's and senile age.

Rules of storage and issue

To store in the dark, dry place at the air temperature which is not exceeding 20 °C.

Period of validity 2 years. To protect from children!

It is released without recipe.