Stimuloton

Stimuloton – synthetic antidepressant.

Pharmacological action of Stimuloton

Active component of Stimuloton has the expressed antidepressant effect, at the same time drug has no stimulating, sedative and anticholinergic properties.

Unlike other drugs having antidepressant effect, Stimuloton, according to reviews, does not cause physical or mental medicinal dependence. Besides, Stimuloton, according to the instruction, does not promote increase in body weight.

Stimuloton has therapeutic effect gradually. The antidepressive effect is, as a rule, celebrated for 10-14 day of regular administration of drug, and stable improvement is observed in one and a half months of reception of Stimuloton.

Release form

Drug Stimuloton is produced in the form of the inodorous oval tablets containing 50 mg (with an engraving of "E271") also by 100 mg (with an engraving of "E272") sertraline.

Excipients – hydrophosphate calcium a dihydrate, magnesium stearate, sodium carboxymethylstarch, a hypro rod, cellulose microcrystallic.

On 10 tablets in packaging.

Stimuloton's analogs

Tablets Asentra, Aleval, Seralin, Zoloft, Thorin and Deprefolt belong to Stimuloton's analogs containing similar active ingredient.

Stimuloton's analogs on a way of action are drugs Aktaparoksetin, Paksil, Oprah, Paroksetin, Apo-Fluoksetin, Plizil, Sedopram, Prozac, Siozam, Flunisan and some other.

Indications to Stimuloton's use

According to the instruction, Stimuloton appoint at:

• Obsessivno-kompulsivnykh frustration, both at adults, and at children of 6 years;
• Posttraumatic stressful frustration;
• Depressions of various etiology, including the states which are followed by feeling of alarm;
• Panic frustration, both with an agoraphobia, and without it.

Contraindications

With the same active ingredient, it is contraindicated to apply drug, as well as Stimuloton's analogs in the following cases:

• Aged up to 18 years, except treatment of the mental disorders connected with persuasive states (ROC);
• At simultaneous use with MAO inhibitors, and also for at least two weeks after their cancellation;
• When breastfeeding;
• At unstable epilepsy;
• At pregnancy;
• At hypersensitivity to Stimuloton's components.

Stimuloton according to the instruction appoint with care at:

• Organic diseases of a brain, including a delay of intellectual development;
• Decrease in body weight;
• Maniacal states;
• Epilepsies;
• Liver and renal failure.

Stimuloton route of administration

The dosage and duration of use of Stimuloton according to the instruction depends on the nature of a mental disorder.

The adult at obsessivno-compulsive frustration and depressions Stimuloton appoint on 1 tablet (50 mg) once a day.

At treatment of panic and posttraumatic stressful frustration within a week about 25 mg of drug then the dose should be doubled are recommended to accept. Gradually if necessary the daily dose can be increased to maximum – 2 tablets of Stimuloton on 100 mg in one step.

As a rule, the lasting antidepressive effect at treatment of a depression is reached within a month.

At therapy of obsessivno-compulsive frustration drug has therapeutic effect more slowly owing to what for a maintenance therapy usually appoint the dose reduced to minimum.

At treatment of the mental disorders connected with persuasive states (ROC) to children at the age of 13-18 years Stimuloton appoint in an initial dose 50 mg once a day, children are 6-12 years old – twice less. The long maintenance therapy, according to the instruction, is recommended to be carried out by Stimuloton in a minimal effective dose.

At renal failures, and also it is not required to people of advanced age of special selection of a dose of Stimuloton. At the carried-out treatment against the background of heavy abnormal liver functions it is necessary or to reduce a drug dose, or to increase an interval between receptions of tablets.

According to the conducted researches, high doses of Stimuloton of heavy symptoms of overdose do not cause. However at administration of drug along with ethanol or drugs containing ethanol the serious poisoning which main symptoms are can develop:

• Nausea, diarrhea and vomiting;
• Tachycardia;
• Dizziness;
• The increased sweating;
• Hyperreflexia;
• Drowsiness;
• Agitation;
• Psychomotor excitement;
• Myoclonus.

Heavy complications can be observed at simultaneous use of Stimuloton with:

• MAO inhibitors;
• Ethanol;
• The drugs contacting proteins of plasma including diazepam, Tolbutamidum and warfarin.

At simultaneous use of drugs of lithium with Stimuloton the probability of development of a tremor increases.

Side effects of Stimuloton

Like other antidepressants, Stimuloton, according to reviews, can cause disturbances from various systems:

• Peripheral and the central nervous system – a hypomania, fatigue, drowsiness, irritability, dizziness, a tremor, a headache, sleeplessness, an akathisia, a mania;
• Cardiovascular system – heartbeat (in rare instances);
• Systems of a hemopoiesis – bleeding, including nasal;
• Reproductive system – disturbance of sexual function, a dysmenorrhea;
• The alimentary system – nausea, decrease or increase in appetite, dryness in a mouth, dyspepsia, spasms in a stomach, anorexia, a meteorism, diarrhea, an unstable chair, vomiting;
• Sense bodys – vision disorders;
• Metabolism – decrease in body weight.

To the most frequent dermatological reactions caused by Stimuloton the increased sweating, and also "inflows" of blood concern to the person and a dermahemia.

With predisposition, according to reviews, the withdrawal can cause the termination of reception of Stimuloton.

In certain cases Stimuloton and analogs of drug can lead to development of a mania or hypomania.

Storage conditions

Stimuloton treats antidepressants which issue from drugstores is possible only in the presence of the recipe. A period of storage of tablets – no more than five years.