Tizin

Tizin – synthetic medicine for topical administration at treatment of some eye diseases, and also for reduction of puffiness of the mucous membrane of a nose caused by allergic or infectious diseases.

Pharmacological action of Tizin

Active component of Tizin, working as alpha адреностимулятор, at topical administration has protivokongestivny and vasoconstrictive effect. At the same time the vasopressor effect develops quickly enough, within several minutes. Drug keeps the action till eight o'clock.

At system use Tizin according to the instruction has the central sedative effect that allows not to apply medicine in addition at night.

Release form

Tizin produce in the form of 0,1% of nasal drops (0,05% – for children) in bottles 10 ml.

Tizin's analogs

Tizin's analogs on active ingredient are the following medicines: Vizin, Vizoptik, Oktiliya and Montevizin.

Besides, in certain cases after consultation with the doctor use of analogs of Tizin on a way of action is allowed. Eye drops Betadrin, Okumetil, Polinadim, Spersallerg, Oftofenazol, Ditadrin and Sanorin-Analergin belong to such drugs.

Indications to Tizin's use

According to the instruction Tizin appoint at treatment:

• Secondary hyperemia against the background of allergic diseases of eyes;
• Chemosis;
• Catarral conjunctivitis;
• Irritations of a conjunctiva.

Besides, Tizin's use is according to reviews effective at hypostasis of a mucous membrane of a nasal cavity against the background of:

• Pharyngitis;
• Rhinitis;
• Hay fever;
• Sinusitis.

Drops Tizin appoint also before holding medical and diagnostic actions (for reduction of puffiness mucous a nose).

Contraindications

Tizin according to the instruction it is contraindicated to apply at hypersensitivity to active or to auxiliary components of drops.

In pediatrics for use of drug there are following contraindications:

• 0,05% solution (both for intranasal use, and in cases of treatment of glaucoma and carrying out endothelial and epithelial dystrophy of a cornea) – up to 2 years;
• 0,1% solution – up to 6 years.

Tizin with care is recommended to apply during treatment by the MAO inhibitors and other medicines promoting increase in arterial pressure at pregnancy and a lactation, and also against the background of:

• Arterial hypertension;
• Thyrotoxicosis;
• Arrhythmias;
• Diabetes mellitus;
• Pheochromocytomas.

Route of administration of Tizin

Tizin is recommended to dig in drops two-three times a day in each conjunctival sac. As a rule, treatment is stopped if improvement does not occur within two days.

Intranazalno Tizin according to the instruction appoint 2-4 drops as children (6 years are more senior), and adults. For children of 2-6 years it is necessary to use 0,05% solution in a one-time dosage 2-3 drops no more than four times a day (with an interval of 3-4 hours).

Duration of continuous use of Tizin should not exceed four days.

Side effects of Tizin

When using Tizin's for treatment of eye diseases can develop:

• Mydriasis;
• Reactive hyperemia;
• Increase in intraocular pressure;
• Burning sensation in eyes.

When using drug as means for a nose Tizin according to reviews can cause:

• Feeling of a pricking or burning in a nose;
• Xeromycteria;
• Sneezing.

At prolonged use Tizin according to reviews can lead to development of a secondary rhinedema.

Besides, active component of Tizin according to reviews can cause system effects which are most often shown in a look:

• Nausea;
• Headache;
• Weaknesses;
• Drowsiness;
• Dizzinesses;
• Tremor;
• Heartbeat;
• Sleeplessnesses;
• Hyperglycemia;
• Tachycardias;
• Disturbances of action of the heart;
• Increases in arterial pressure;
• Allergic reactions.

Prolonged use of Tizin, and also exceeding of therapeutic doses in certain cases leads to overdose which is shown usually as:

• Cyanosis;
• Mydriasis;
• Cardiac standstill;
• Spasms;
• Fever;
• Increase in arterial pressure;
• Arrhythmias;
• Диспноэ;
• Fluid lungs;
• Oppression of the central nervous system which is followed by drowsiness, a hypothermia, an apnoea, a collapse, bradycardia and a coma.

The risk of emergence of these symptoms caused by drug absorption is highest at small children and arises most often at a proglatyvaniye of medicinal solution.

For treatment appoint, as a rule, a gastric lavage, oxygen inhalations, absorbent carbon, and also the drugs reducing the arterial pressure, body temperature and antiepileptic means.

Medicinal interaction

Tizin according to the instruction it is impossible to apply along with MAO inhibitors.

Storage conditions of Tizin

Drops Tizin are released on doctor's orders. A drug period of storage – 5 years, an open bottle of Tizin it is not necessary to use longer than month from the moment of its opening.