Amiksin

Drug possesses immunomodulatory action, i.e. increases immunity.

Pharmacological action

Amiksin represents the effective synthetic inductor which stimulates synthesis of the interferon belonging to type an alpha, a beta and scale.

The main active ingredient of Amiksin is типорон to which introduction hepatocytes (a liver cell), granulocytes (one of subgroups of white blood cells) and T lymphocytes (the lymphocytes developing in a thymus) react and intestines epithelium cells, actively producing interferon.

After Amiksin's use the maximum quantity of interferon is developed within 4-24 hours, first of all on типорон intestines react, then – a liver, and in the last turn – blood. Drug has antiviral and immunomodulatory effect.

Amiksin's use is effective at treatment many viral infections, including influenza viruses, respiratory viral infections caused by other activators and also viruses of hepatitis and herpes. Antiviral action of Amiksin is caused by his ability to suppress a reproduction of viruses by broadcasting inhibition in the infected cells a virus proteins.

According to responses, Amiksin considerably surpasses the analogs in harmlessness, action duration, the gained effect and the latitude of the sphere of use. This drug is well transferred and is not toxic.

Amiksin after oral administration is quickly soaked up, bioavailability (ability to be acquired) – 60%, linkng with proteins of plasma – 80%. Practically in an invariable look it is removed through kidneys (9%) and intestines (70%). Amiksin does not collect in an organism and is not exposed to biotransformation.

Indications to Amiksin's use

Clinical trials and comments on Amiksin confirm expediency of purpose of drug at the following diseases:

• prevention and treatment of flu and SARS;
• Cytomegaloviral infection;
• herpes;
• viral hepatitis And, In and Page.

In the instruction to Amiksin it is specified that perhaps effective use of drug as a part of complex therapy of such diseases:

- viral and infectious and allergic encephalomyelitis;

- respiratory and urogenital clamidiosis;

- pulmonary tuberculosis.

For treatment of flu and a SARS to children 7 years are more senior Amiksin children's is appointed.

Route of administration of Amiksin

Drug is produced in the form of tablets, coated, on 60 mg (Amiksin children's) and on 125 mg. This medicine should be taken orally on the termination of meal. To adult patients of a tablet on 125 mg are appointed according to the following scheme:

• Prevention of flu and SARS – within 6 weeks it is necessary to accept on 1 tablet once a week.
• Treatment of flu and SARS – 6 tablets are distributed as follows: the first two days on 1 tablet a day, the remained pill are taken at an interval of 48 hours.
• Acute hepatitis In – Amiksin is accepted according to the same scheme as well as at flu, the course consists of 16 tablets.
• Acute gepapit With – drug is accepted according to the same scheme as well as at flu, the course consists of 20 tablets.
• Viral hepatitis And – according to the instruction, Amiksin it is necessary to accept 1 tablet two times a day the first two days, then every 48 hours on 1 tablet. For all course 10 pill have to be taken.
• Chronic hepatitis B – in an initial phase it is necessary to accept the first two days on 1 tablet two times a day, then on 1 tablet – through each two days (only 20 tablets). Amiksin's use in number of 10-20 tablets is provided by a continuation phase during which reception of 1 tablet is carried out once a week. The course dose (30-50 tablets) is expected 3,5-6 months.
• Chronic hepatitis C – the scheme of use of drug same, as at treatment of chronic hepatitis B. The course (50 tablets) is expected half a year.
• Complex therapy of neuroviral infections – is appointed the first two days on 1-2 tablet, then through each two days on 1 tablet.
• Herpes and Cytomegaloviral infection – the scheme of use of Amiksinn corresponds to a dose and frequency rate of receptions at treatment of flu. The course consists of 10-20 tablets.
• Respiratory and urogentalny clamidiosis – treatment occurs in the same way, as well as treatment of flu. The course dose includes 10 tablets.
• Complex therapy of a pulmonary tuberculosis – on 2 tablets the first two days, then on 1 tablet each 48 hours. The course consists of 20 tablets.

Treatment of flu and SARS without complications at children is more senior than 7 years is carried out by means of Amiksin children's which 1 tablet includes 60 mg of a tiloron: in the first, second and fourth day from an initiation of treatment about 1 tablet is appointed. If flu or a SARS are followed by complications, then in addition one more is appointed to the sixth day from an initiation of treatment, the fourth, Amiksin's tablet children's.

Side effects

In comments on Amiksin complaints to undesirable effects after administration of drug extremely seldom meet, however there is a probability of such side effects as allergic reaction and a fever (not for long). Disturbances in functioning of system of digestion are possible.

Contraindications

In the instruction to Amiksin it is specified that it is necessary to refrain from use of drug in the following cases:

- hypersensitivity;

- pregnancy;

- to women during feeding by a breast;

- to children up to 7 years.

Additional information

The place of storage of drug has to be dark and dry, and temperature - within ^5-300C. A period of validity of Amiksin – 3 years.