Dihydrotachysterolum
Application instruction:
Dihydrotachysterolum – the drug regulating exchange of phosphorus and calcium in an organism.
Form of release and structure
Dihydrotachysterolum produce in the form of drops for intake 0,1% (in dark glass bottles or bottles droppers on 10, 15, 20, 30 or 50 ml).
Are a part of 1 ml of drops:
- Active agent: Dihydrotachysterolum – 1 mg;
- Auxiliary components: the sunflower or soy refined deodorized oil – to 1 ml.
Indications to use
- Tetany (muscular spasms which are caused by a hypocalcemia);
- Pseudohypoparathyroidism;
- Hypoparathyrosis (postoperative and idiopathic);
- The diseases of bones caused by deficit of vitamin D.
Contraindications
- Hypervitaminosis of D;
- Hypercalcemia;
- Hypersensitivity to drug components, and also to other drugs of vitamin D.
Route of administration and dosage
Dihydrotachysterolum is accepted inside.
Frequency rate of reception is defined by indications and concentration of calcium in urine and blood. Usually daily dose varies from 0,25 to 1,5 mg.
Side effects
During therapy development of the following side effects is possible:
- Urinary system: at long treatment – functional disturbances of kidneys;
- Cardiovascular system: heartbeat; seldom – disturbances of a cordial rhythm;
- Alimentary system: diarrhea, anorexia, vomiting, nausea; at reception in high doses – dyskinesia of biliary tract;
- Metabolism: calcification of fabrics, thirst;
- Others: headache, pallor of integuments.
Special instructions
Patients with an urolithiasis should take Dihydrotachysterolum with caution.
The concomitant use of Dihydrotachysterolum with other vitamins of group D, parathyroid means and drugs of calcium is not recommended.
Patients with allergic reactions to nuts (including an allergy to a peanut) should not accept drug.
At simultaneous use with replacement therapy need for correction of the mode of dosing of Dihydrotachysterolum can arise thyroid hormones.
Medicinal interaction
At combined use of Dihydrotachysterolum with some medicines there can be undesirable effects:
- Cardiac glycosides and antagonists of calcium: strengthening of their action is possible (decrease in their doses can be required);
- Rifampicin, thiazide diuretics, vitamin D, and also calciferous drugs and nutritional supplements: development of a hypercalcemia is possible;
- Liquid paraffin, barbiturates (phenobarbital), anion-exchange pitches (колестипол, Colestyraminum), antiepileptic means (carbamazepine (Finlepsinum), Phenytoinum (dipheninum), Primidonum (hexamidine)): weakening of action of Dihydrotachysterolum is possible.
At simultaneous use with thyroxine, after its cancellation the hypercalcemia can develop.
Terms and storage conditions
To store in protected from light, the place, unavailable to children, at a temperature of 0-15 °C.
Period of validity – 2,5 years.
Name of drug
Price
Drugstore
Dihydrotachysterolum solution in masle1mg/ml фл 10 ml, the Echo of NPK (г.Москва)
343 rub.
Network of the Moscow drugstores of IFCHaving fallen from a donkey, you more likely will kill yourself, than having fallen from a horse. Only do not try to disprove this statement.
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