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Chlorprothixene

The prices in Internet drugstores:

from 201 rub.

Chlorprothixene – a neuroleptic, Упаковка Хлорпротиксенantipsychotic medicine.

Structure and form of release

Drug release in the form of biconvex round tablets, film coated, containing active ingredient – chlorprothixene a hydrochloride of 15 or 50 mg.

Additional components: monohydrate of lactose, talc, corn starch, calcium stearate, sucrose.

In blisters on 10 tablets.

Analog of Chlorprothixene is medicine Truxal.

Pharmacological effect of Chlorprothixene

Use of Chlorprothixene renders antipsychotic effect on an organism, thanks to the blocking impact on dopamine receptors. Blockade of these receptors makes also analgeziruyushchy and antiemetichesky impact.

According to the instruction Chlorprothixene blocks H1 - histamine receptors, α1 – adrenoceptors, 5-HT2 – receptors owing to what drug has hypotensive, adrenoceptor blocking and antihistaminic effect.

Indications to Chlorprothixene use

According to the instruction Chlorprothixene has quite wide range of indications among which there is following:

• a behavior disorder at children;

• sleeplessness;

• psychoses, among which the maniacal states and schizophrenia proceeding with alarm, agitation and psychomotor excitement;

• psychosomatic frustration, neurosises, depressions;

• irritability, a hyperactivity, confusion of consciousness, excitement at people of old age;

• pains (as a part of a combination therapy);

• a hungover abstinence syndrome at drug addiction and alcoholism.

Contraindications

• hypersensitivity to one or several components of drug;

• vascular collapse;

• pheochromocytoma;

• coma;

• diseases of bodies of a hemopoiesis;

• oppression of TsNS of various etiology (including at reception of opiates, barbiturates and alcohol).

Route of administration of Chlorprothixene and mode of dosing

At psychoses, maniacal states and schizophrenia the initial dosage of drug or an analog of Chlorprothixene makes 50-100 mg a day with gradual increase in a dosage up to 300 mg a day. In especially hard cases increase in a dosage up to 1200 mg a day is allowed. The daily dosage is divided, as a rule, into three receptions. It is recommended to accept the most part of a dose in the evening that is connected with the expressed sedative effect of drug. The supporting dosage makes 100-200 mg a day.

At a hungover abstinence syndrome use of Chlorprothixene makes 500 mg divided into two or three receptions. Usually duration of treatment lasts one week. After disappearance of symptoms of an abstinence syndrome it is recommended to reduce gradually a dosage to supporting – 15-45 mg a day which reduces risk of development of the next hard drinking and stabilizes the general condition of an organism.

To patients of old age with irritability, a hyperactivity, confusion of consciousness and nervous excitement the initial dosage makes 15-90 mg the day divided into three receptions.

To children appoint Chlorprothixene according to the instruction for correction of behavior disorders. The dosage is calculated proceeding from 0,5-2 mg on weight kg.

At psychosomatic frustration and depressions drug is usually accepted as a part of a combination therapy. The dosage in this case, as a rule, makes up to 90 mg the day divided into two-three receptions.

As drug or an analog of Chlorprothixene does not cause medicinal dependence and accustoming, it can be applied throughout a long period.

At sleeplessness drug accept in a dosage 15-30 mg in one hour prior to a dream.

As Chlorprothixene has analgeziruyushchy properties, it can be used at pains along with other analgetics. Appoint, as a rule, from 15 to 300 mg a day.

Pregnancy and breastfeeding

Whenever possible, it is not recommended to appoint Chlorprothixene during pregnancy and breastfeeding.

Side effects of Chlorprothixene

According to reviews Chlorprothixene can cause the following by-effects from different systems of life activity:

• dysmenorrhea;

• dizziness;

• tachycardia;

• difficulty of accommodation;

• dryness in a mouth;

• skin rashes;

• the increased perspiration;

• hemolitic anemia;

• tranzitorny high-quality leukopenia;

• lock;

• extrapyramidal symptoms;

• drowsiness;

• decrease in a convulsive threshold.

At long receptionТаблетки Хлорпротиксен Chlorprothixene according to reviews can cause orthostatic hypotension, increase in body weight, cholestatic jaundice, a gynecomastia, increase in appetite, decrease in a libido, a galactorrhoea.

Overdose

The overdose by Chlorprothixene according to reviews causes the following symptoms: hyper - or a hypothermia, spasms, extrapyramidal symptoms, a coma, shock.

In case of overdose it is necessary to carry out the symptomatic and supporting treatment.

Medicinal interaction of Chlorprothixene

At simultaneous use of Chlorprothixene with:

• anesthetics, neuroleptics, hypnotic drugs, sedatives, analgetics, opiodny and etanolsoderzhashchy drugs its action on TsNS can amplify;

• antihistaminic, anticholinergic, protivoparkinsonichesky drugs anticholinergic effect of drug amplifies;

• antihypertensives their effect amplifies;

• adrenaline can lead to development of tachycardia and arterial hypotension;

• a levodopa decreases actions of the last;

• a haloperidol, Metoclopramidum, fenotiazina, Reserpinum can lead to emergence of extrapyramidal frustration.

Storage conditions

Store drug in the dry cool place not longer than three years.

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Chlorprothixene тбл п / about 15 mg No. 30, Zentiva A.C.

201 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC

Chlorprothixene of a tablet 50 of Mg of 30 pieces

295 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Chlorprothixene тбл п / about 15 mg No. 50, Zentiva A.C.

297 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC

Chlorprothixene тбл п / about 50 mg No. 30, Zentiva A.C.

304 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC

n50 mg chlorprothixene 15 таб.

309 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC
 
 
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