Kolpotrofin

Kolpotrofin – the medicine recovering a vaginal epithelium and promoting its proliferation.

Form of release and structure

Dosage forms:

• Capsules vaginal (on 10 pieces in packaging);
• Cream vaginal 1% (on 15 g in tubas).

Active ingredient of Kolpotrofin – проместриен. Its content is to 1 capsule and 1 g of cream – 10 mg.

Auxiliary components of capsules: sodium methylparahydroxybenzoate, диметикон, sodium пропилпарагидроксибензоат, polyisobutene pergidrogenizirovanny, anhydrous oxide of silicon colloid, sorbitan sesquioleate, gelatin, white soft paraffin, the water purified.

Auxiliary components of cream: sodium methylparahydroxybenzoate, glycerin, sodium пропилпарагидроксибензоат, polyglycol ethers of saturated fatty alcohols, decyloleate, mix mono - and diglycerides of saturated fatty acids, triglycerides of an average chain, the water purified.

Indications to use

For vaginal capsules:

• Treatment of the urogenital frustration which developed owing to deficit of estrogen, including dryness and an itch in a vagina, recurrent vaginit, a dispareuniya (pain in a small pelvis or external genitals), urine incontiences;
• Recovery of a vulval epithelium after inflammatory processes;
• Postoperative therapy during the period after removal of ovaries;
• Before - and postoperative therapy at surgical intervention in the intravaginalny way;
• Preparation of a neck of uterus for childbirth;
• Puerperal recovery of a vagina and neck of uterus;
• Recovery therapy after surgical treatment of an erosion of an epithelium of a neck of uterus.

For vaginal cream:

• Treatment of synechias;
• Postoperative therapy during the period after removal of ovaries;
• Treatment of the urogenital frustration caused by deficit of estrogen including dryness and an itch in a vagina, an incontience of urine, a dispareuniya;
• Puerperal recovery of a vagina, crotch and vulva in case of their damage;
• Before - and postoperative therapy at surgical intervention in the intravaginalny way.

Contraindications

Kolpotrofin's use is strictly contraindicated in the following cases:

• Estrogenzavisimy tumors (breast cancer, endometria tumors);
• Lactation;
• Hypersensitivity to drug components.

Route of administration and dosage

Capsules enter into a vagina 1 piece a day:

• Urogenital frustration: within 20 days. If necessary the doctor can adjust a dose and duration of treatment, to appoint a maintenance therapy;
• Healing of an epithelium of a neck of uterus: for 10 days, if necessary – it is more;
• Before - and postoperative therapy: within 10-20 days before operation and as much later;
• Preparation of a neck of uterus for childbirth: 5-6 days before estimated date of delivery;
• Healing of a neck of uterus and vagina after the delivery: within 10 days.

Cream use Kolpotrofin:

• Urogenital frustration: apply with a thin layer on a vagina, a vulva and an urethra and the easy massing movements rub, the first week – 1 time a day, the next 3 weeks – 1 time every other day. If necessary the dose and duration of treatment are adjusted by the doctor. Carrying out a maintenance therapy is possible;
• Before - and postoperative therapy: 1 time a day within 10-20 days before operation and as much after it;
• Healing of a crotch, vagina and vulva after the delivery: 1 time a day within 10 days;
• Synechias: 1 time a day before their discrepancy, duration of therapy is not limited.

Side effects

Kolpotrofin is generally had well, allergic reactions in the form of an itch and irritation are in rare instances noted local (in a site of application of cream or introduction of the capsule).

Special instructions

Drug is used during pregnancy by preparation of a neck of uterus for childbirth, and also for healing of fabrics in a parturient canal in a puerperal period. During other periods of pregnancy the doctor can appoint Kolpotrofin, having carefully estimated the expected advantage and potential risks. During a lactation it is contraindicated to use drug.

In case of development of the uterine bleeding which is not connected with a menstrual cycle it is necessary to carry out symptomatic therapy.

Girls of pubertal age can appoint cream for treatment of synechias. Capsules are contraindicated to use in pediatrics.

Medicinal interaction

The women who are receiving medical treatment for Kolpotrofin should mean that drug:

• Inactivates action of spermicidal means;
• Reduces condom durability, than increases risk of its gap (because of the oily substances and lubricants which are a part).

Terms and storage conditions

To store at a temperature: cream – 9-14 ºС, capsules – 14-24 ºС.

Period of validity – 5 years.