Pastils: round, light brown, with a peppermint smell (in blisters on 10 pieces, on 1, 2 or 4 blisters in a cardboard pack);
Tablets: round, slightly yellowish or white, flat from two parties, with slanted edges, on one of the parties – dividing risk and the text "67C" which is squeezed out on both sides from it, on another – a symbol of firm (in blisters on 10 pieces, on 2 or 5 blisters in a cardboard pack);
Syrup: almost colourless or colourless, almost transparent or transparent, with a smell of wild berries (on 15 mg / 5 ml) or a strawberry smell (on 30 mg / 5мл), slightly viscous (in dark glass bottles on 100, 200 or 250 ml complete with a measured glass or without it, on 1 bottle in a cardboard pack);
Solution for intake and inhalations: transparent, slightly brownish color or colourless (in dark glass bottles on 100 ml complete with a dosing glass or a beaker, on 1 bottle in a cardboard pack).

Is a part of 1 pastil:

Active agent: Ambroxol – 15 mg (in the form of a hydrochloride);
Auxiliary components: acacia gum – 850 mg, sorbitol – 307,4 mg, Karionum 83 (Mannitolum, sorbitol, the hydrogenated hydrolyzed starch) – 614,8 mg, oil of leaves of a peppermint – 10 mg, oil of leaves of a prutovidny eucalyptus – 2 mg, sodium saccharinate – 1,8 mg, liquid paraffin (the purified mix of liquid saturated hydrocarbons) – 2,4 mg, the purified water – 196,6 mg.

Is a part of 1 tablet:

Active agent: Ambroxol – 30 mg (in the form of a hydrochloride);
Auxiliary components: monohydrate of lactose – 171 mg, the dried-up corn starch – 36 mg, colloid silicon dioxide – 1,8 mg, magnesium stearate – 1,2 mg.

Is a part of 5 ml of syrup:

Active agent: Ambroxol – 15 or 30 mg (in the form of a hydrochloride);
Auxiliary components (on 15/30 mg in 5 ml respectively): the benzoic acid – 8,5/8,5 mg, hydroxyethylcellulose (gietelloza) – 10/10 mg, to potassium atsesulfa – 5/5 mg, liquid sorbitol (uncrystallizable) – 1750/1750 mg, глицерол 85% – 750/750 mg, vanilla fragrance 201629 - 3/3 of mg, the purified water – 3047,5/3031,5 mg, fragrance PHL-132195 wild berry – 11 mg (for syrup of 15 mg / 5 ml) or strawberry and creamy PHL-132200 fragrance – 12 mg (for syrup of 30 mg / 5 ml).

For intake and inhalations enters into structure of 1 ml of solution:

Active agent: Ambroxol – 7,5 mg (in the form of a hydrochloride);
Auxiliary components: monohydrate of citric acid – 2 mg, a hydrosodium phosphate dihydrate – 4,35 mg, sodium chloride – 6,22 mg, chloride a benzalkoniya – 0,225 mg, the purified water – 989,705 mg.

Indications to use

Lazolvan appoint for treatment of the following acute and chronic diseases of respiratory tracts which proceed with allocation of a viscous phlegm:

Bronchoectatic disease;
Pneumonia;
Bronchitis in an acute and chronic current;
The bronchial asthma proceeding with difficulty of an otkhozhdeniye of a phlegm;
Chronic obstructive pulmonary disease.

Contraindications

First trimester of pregnancy and period of a lactation;
Hypersensitivity to drug components.

Lazolvan pregnant women should apply with care in the II-III trimeters, and also at a renal and/or liver failure.

Children depending on a dosage form Lazolvan can accept:

Pastils and syrup of 30 mg / 5 ml: since 6 years;
Tablets: since 18 years.

Pastils in terms of the maximum recommended daily dose (90 mg) contain 3200 mg of sorbitol therefore patients with rare hereditary intolerance of fructose should not accept Lazolvan in this dosage form.

Lazolvan in the form of tablets it is contraindicated to patient to accept with deficit of lactase, a lactose intolerance and glyukozo-galaktozny malabsorption.

Patients cannot accept syrup with hereditary intolerance of fructose.

Route of administration and dosage

Lazolvan apply inside or it is inhalation.

Inside drug can be accepted regardless of meal time.

Pastils need to be rassasyvat slowly in a mouth, a pill should be taken, washing down them with liquid, solution can be dissolved in juice, tea, milk or water.

As a rule, Lazolvan inside appoint:

Pastils: adults and children of 12 years – 3 times a day on 2 pastils; children of 6-12 years – 2-3 times a day on 1 pastil;
Tablets: 3 times a day on 1 tablet; for strengthening of therapeutic effect increase in a daily dose is possible (2 times a day on 2 tablets);
Syrup of 15 mg / 5 ml: adults and children of 12 years – 3 times a day on 10 ml; children of 6-12 years – 2-3 times a day on 5 ml; children of 2-6 years – 3 times a day on 2,5 ml; children up to 2 years – 2 times a day on 2,5 ml;
Syrup of 30 mg / 5 ml: adults and children of 12 years – 3 times a day on 5 ml; children of 6-12 years – 2-3 times a day on 2,5 ml;
Solution for intake (1 ml = 25 drops): adults and children of 12 years – 3 times a day on 100 drops; children of 6-12 years – 2-3 times a day on 50 drops; children of 2-6 years – 3 times a day on 25 drops; children up to 2 years – 2 times a day on 25 drops.

It is inhalation Lazolvan usually appoint:

Adults and children of 6 years – 1-2 inhalations on 2-3 ml of solution a day;
Children up to 6 years – 1-2 inhalations on 2 ml of solution a day.

For inhalations it is possible to use any modern equipment intended for this purpose (except steam inhalers). To provide optimum moistening at inhalations Lazolvan it is necessary to mix from 0,9% sodium chloride solution in a proportion 1:1. As during inhalation therapy the deep breath can lead to development of cough, inhalations need to be carried out, keeping a usual respiratory rhythm. Before the procedure inhalation solution of Lazolvan is recommended to be warmed up to body temperature. Patients with bronchial asthma are recommended to carry out inhalation after reception of broncholitic medicines that will help to avoid nonspecific irritation of respiratory tracts and their spasm.

At preservation of symptoms of a disease for 4-5 days from the moment of the beginning of reception of Lazolvan it is recommended to see a doctor.

Side effects

As a rule, Lazolvan, is had well.

During therapy the following side effects can develop:

Digestive tract: often – nausea, decrease in sensitivity in a cavity of a gullet or a mouth; infrequently – diarrhea, dyspepsia, heartburn, vomiting, pains in the field of an upper part of a stomach, dryness of a mucous membrane of a cavity of a throat and mouth;
Nervous system: often – disturbance of flavoring feelings;
Immune system, skin and hypodermic fabrics: seldom – urticaria, rash, a Quincke's disease, anaphylactic reactions (including an acute anaphylaxis), an itch and other allergic reactions.

Special instructions

It is not necessary to combine Lazolvan with the antibechic drugs complicating removal of a phlegm.

At patients with severe damages of skin (a toxic epidermal necrolysis or Stephens-Johnson's syndrome) in an early phase temperature can increase, appear rhinitis, body pain, an inflammation of a throat and cough. At symptomatic therapy perhaps wrong purpose of mucolytic drugs, such as Lazolvan. There are single messages on identification of a toxic epidermal necrolysis and Stephens-Johnson's syndrome which matched on time its appointment, however relationship of cause and effect with Lazolvan's reception is absent.

In case of development of above-mentioned syndromes it is necessary to interrupt use of drug and to ask immediately for the help the doctor.

At functional disturbances of kidneys Lazolvan it is possible to apply only on doctor's orders.

162,5 mg of lactose, in the maximum daily dose (4 tablets) – 650 mg of lactose are a part of 1 tablet.

The sorbitol which is a part of syrup can render insignificant laxative effect. The maximum recommended daily dose of syrup contains 5 g (in 20 ml of syrup of 30 mg / 5 ml) or 10,5 g (in 30 ml of syrup of 15 mg / 5 ml) sorbitol.

Solution for intake and inhalations contains preservative chloride a benzalkoniya which during performing inhalation can cause a spasm of bronchial tubes in patients with a hyperreactivity of respiratory tracts. Solution is not recommended to be mixed with alkaline solutions and kromoglitsiyevy acid. Increase in value рН solution above 6,3 can give to loss of a deposit of active agent or emergence of opalescence.

Patients who keep to a diet with the lowered content of sodium need to consider that (for adults and children of 12 years) Lazolvana in the form of solution for intake and inhalations contains in the recommended daily dose 42,8 mg of sodium.