Main > Drugs> Unithiolum

Unithiolum

The prices in Internet drugstores:

from 369 rub.

Unithiolum – means for desintoxication and treatment of poisonings.

Pharmacological action of Unithiolum

Drug is created Упаковка Унитиолon the basis of active ingredient – Dimercaprolum. He acts by the principle of an antidote, interacting with thiol poisons.

Thiol poisons are called substances which contact sulphhydryl groups of enzymes and suppress their activity. Incorporating two free sulphhydryl groups, dimercaptol enters a neutralization test with thiol poisons and forms with them non-toxic and safe complexes which are easily brought out of an organism. Thus, sulphhydryl groups of enzymes remain, and neutralization of poisons recovers functions of the blocked fabric enzymes again.

The earlier the drug will be administered in an organism, the more effectively it will contact poisons, so, will have the medical effect.

Unithiolum is capable to increase removal of ions of some metals (for example, zinc and copper) from metallic enzymes of cells. This its property is used in treatment of the diseases connected with disturbance of exchange of copper or zinc. For example, at Wilson-Konovalov's disease when excess of copper accumulates in subcrustal kernels of a brain.

At a diabetes mellitus when it was complicated by diabetic polyneuropathy, in blood and fabrics deficit of sulphhydryl groups is formed. In this case, and also at a secondary amyloidosis Unithiolum is capable to improve work of a peripheral nervous system. It also reduces permeability of capillaries and reduces pains.

The drug is administered parenterally, it is quickly soaked up from an injection site in a circulatory bed where contacts thiol poisons, and removed with urine in partially oxidized or not changed look. The elimination half-life makes 1 – 2 hour. Unithiolum does not collect in an organism.

Release form

According to the instruction Unithiolum is released in the form of 5% of solution in ampoules on 5 ml.

Indications to use of Unithiolum

According to the instruction Unithiolum is used for treatment of poisonings with mercury salts, chrome, arsenic, bismuth and other heavy metals. Removal of lead salts carries out Unithiolum less effectively.

Drug is effective as an antidote at poisonings with cardiac glycosides.

Apply it and at poisonings cordial glycosides, and also in complex therapy of an alcoholism.

Unithiolum received good comments in complex therapy of an alcoholism.

Contraindications

It is impossible to use Ампула Унитиолdrug at severe damages of a liver, the increased arterial pressure. The doctor will also not write out the recipe on Unithiolum at its individual intolerance.

Application instruction of Unithiolum

Drug is intended for intramuscular or hypodermic introduction. At poisoning with mercury salts and arsenic it is entered at the rate of a single dose - 1 ml of 5% of solution for 10 kg of body weight of the person. In the first day of treatment 3 – 4 introductions (on a condition of the patient), in the second day – 2 – 3 injections, in the third and the next days – on 1 – 2 injection are necessary. At poisoning with mercury treatment has to last at least 6 days, before disappearance of symptoms of intoxication.

For overdose elimination by cardiac glycosides the scheme of introduction the same, before elimination of symptoms of cardiotoxic action.

Treatment of poisonings except Unithiolum has to include necessary standard actions (infusion of solutions intravenously and an artificial diuresis, a gastric lavage, an enema, etc.).

At Wilson-Konovalov Unitiol's disease enter 5 – 10 ml intramusculary every day or in a day. The course makes 25 – 30 injections, if necessary in 3 – 4 months it can be repeated.

In complex treatment of an alcoholism Unithiolum is entered on 3 – 5 ml by 2 – 3 times a week.

At diabetic neuropathy the scheme of purpose of drug simple – on 5 ml intramusculary, 10 injections on a course.

According to the recipe Unithiolum can be got practically in any drugstore.

Side effects

According to reviews Unithiolum is transferred well, it is seldom capable to cause heartbeat increase, nausea, dizziness. Usually they pass independently.

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Unithiolum solution of 5% 5 ml 10 pieces

369 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Unithiolum solution for инъ 5% of amp of 5 ml No. 10 *, Moskhimfarmpreparata of Semashko

504 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC
 
 
Whether you know that:

If to smile all twice a day – it is possible to lower blood pressure and to reduce risk of developing of heart attacks and strokes.