Флюколдекс

Флюколдекс – multicomponent medicine for a symptomatic treatment of catarrhal and infectious diseases. Reviews of Flyukoldeksa confirm high medical performance and speed of a medicine.

Drugs to Terafl, Ekstratab, Ferveks, Efferalgan with vitamin C, Kaffetin of SK, Grippostad With - Flyukoldeks's analogs.

Form of release and Flyukoldeks's list

Флюколдекс it is made in the form of tablets, and also in the form of suspension.

Paracetamol (500 mg), caffeine anhydrous (30 mg), a fenilpropanolamina a hydrochloride (25 mg), хлорфенираминамалеат (2 mg), and also additional components is a part of each tablet of Flyukoldeks: Natrium benzoicum, starch, gelatin, magnesium stearate, talc, polyvinylpirrolidone, sorbitol, sodium krakhmalglikolit, dye sanst yellow.

5 ml of suspension of Flyukoldeks contain 125 mg of paracetamol and 2 mg of chlorphenaminum of a maleate.

Pharmacological action

Флюколдекс – the combined medicine. Flyukoldeksaparatsetamol who is a part has febrifugal and analgeziruyushchy effect. Paracetamol influences the centers of thermal control and pain, blocking TsOG only in the central nervous system. Hlorfenaminamaleat possesses antipruritic, antimuskarinovy, spasmolytic, antiedematous, antiexudative antiallergic action (blocks histamine H1 receptors). Besides, хлорфенаминамалеат has overwhelming effect on TsNS, promotes reduction of permeability of capillaries.

Caffeine has the expressed promoting effect on a cerebral cortex, the vasomotor and respiratory centers that is shown in increase in force and increase in ChSS, arterial pressure at hypotension. Effect of this substance promotes increase in intellectual and physical working capacity, reduction of feeling of fatigue and drowsiness. Caffeine weakens action of components, the oppressing TsNS.

Indications to Flyukoldeks's use

Indications to Flyukoldeks's use according to the instruction following:

• feverish syndrome (infectious and catarrhal diseases);
• pain syndrome (migraine, arthralgia, neuralgia, mialgiya, head and dentagra);
• rhinorrhea (allergic rhinitis, acute rhinitis);
• sinusitis.

Contraindications

• hypersensitivity to any component of Flyukoldeks;
• children's age up to six years;
• deficit glyukozo-6-fosfatdegidrogenazy;
• renal and/or liver failure;
• lactation period;
• pregnancy;
• thyrotoxicosis;
• heart failure (chronic form);
• diabetes mellitus;
• blood diseases;
• arterial hypertension;
• analgetic nephropathy;
• prostate hyperplasia;
• pheochromocytoma.

Флюколдекс it is necessary to apply with care at an inborn hyperbilirubinemia (Gilbert's syndromes, the Rotor and the Cudgel Johnson), alcoholism, closed-angle glaucoma, a prostate hyperplasia, at advanced age.

The instruction to use

According to the instruction of Flyukoldeks in the form of suspension it is necessary to apply in the following standard doses:

• children are 3-5 years old – on 5 ml twice a day;
• to children at the age of 6-10 years – on 5 ml three-four times a day;
• to children of 10-15 years – on 10 ml three times a day;
• to adults and teenagers since 16 years – on 10 ml of suspension from four to six times a day.

Course of treatment – five days.

Флюколдекс in tablets adults are recommended to apply two-three times a day (on one tablet).

Judging by reviews of Flyukoldeksa, drug is in most cases transferred well. However the following side effects are possible: deterioration in appetite, dizziness, dryness of mucous membranes, increase in the ABP, stimulation TsNS, vomiting, irritation of a GIT, allergic reactions, epigastric pain, hemolitic disturbances, ischuria.

Some reviews of Flyukoldeksa demonstrate that at prolonged use the medicine has a hepatotoxic action. Besides, prolonged use of Flyukoldeks in high doses can lead to development of a glucosuria, intersticial nephrite, a papillary necrosis.

Medicinal interaction

• prolonged combined use of Flyukoldeks and barbiturates promotes decrease in efficiency of paracetamol;
• paracetamol reduces effect of uricosuric medicines and raises an effektinost of indirect anticoagulants;
• long simultaneous use of paracetamol and other NPVS increases risk of development of a renal papillary necrosis and "analgetic" nephropathy;
• Diflunisal increases concentration of paracetamol in a blood plasma for 50% (risk of development of a hepatotoxic);
• myelotoxic drugs strengthen manifestations of a hepatotoxic of Flyukoldeks;
• joint long use in treatment of salicylates and paracetamol in high doses increases risk of development of cancer of bladder.